| Full name: TATA-box binding protein associated factor 5 | Alias Symbol: TAFII100 | ||
| Type: protein-coding gene | Cytoband: 10q24.33 | ||
| Entrez ID: 6877 | HGNC ID: HGNC:11539 | Ensembl Gene: ENSG00000148835 | OMIM ID: 601787 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF5 | 6877 | 210053_at | 0.8672 | 0.0286 | |
| GSE20347 | TAF5 | 6877 | 210053_at | 0.8188 | 0.0000 | |
| GSE23400 | TAF5 | 6877 | 210053_at | 0.4069 | 0.0000 | |
| GSE26886 | TAF5 | 6877 | 210053_at | 0.5583 | 0.0138 | |
| GSE29001 | TAF5 | 6877 | 210053_at | 0.9305 | 0.0018 | |
| GSE38129 | TAF5 | 6877 | 210053_at | 0.7650 | 0.0000 | |
| GSE45670 | TAF5 | 6877 | 210053_at | 0.5326 | 0.0004 | |
| GSE53622 | TAF5 | 6877 | 39426 | 0.4419 | 0.0000 | |
| GSE53624 | TAF5 | 6877 | 39426 | 0.7547 | 0.0000 | |
| GSE63941 | TAF5 | 6877 | 210053_at | 0.3860 | 0.4763 | |
| GSE77861 | TAF5 | 6877 | 210053_at | 0.6292 | 0.1869 | |
| GSE97050 | TAF5 | 6877 | A_23_P52311 | 0.2170 | 0.4754 | |
| SRP007169 | TAF5 | 6877 | RNAseq | 0.8997 | 0.1149 | |
| SRP064894 | TAF5 | 6877 | RNAseq | 0.1573 | 0.3081 | |
| SRP133303 | TAF5 | 6877 | RNAseq | 0.4986 | 0.0025 | |
| SRP159526 | TAF5 | 6877 | RNAseq | 0.7274 | 0.0060 | |
| SRP193095 | TAF5 | 6877 | RNAseq | 0.3323 | 0.0009 | |
| SRP219564 | TAF5 | 6877 | RNAseq | 0.3199 | 0.4149 | |
| TCGA | TAF5 | 6877 | RNAseq | 0.2295 | 0.0018 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF5 | 6877 | 2 | 9 | 19 | |
| GSE20123 | TAF5 | 6877 | 2 | 8 | 20 | |
| GSE43470 | TAF5 | 6877 | 0 | 8 | 35 | |
| GSE46452 | TAF5 | 6877 | 0 | 11 | 48 | |
| GSE47630 | TAF5 | 6877 | 2 | 14 | 24 | |
| GSE54993 | TAF5 | 6877 | 8 | 0 | 62 | |
| GSE54994 | TAF5 | 6877 | 1 | 10 | 42 | |
| GSE60625 | TAF5 | 6877 | 0 | 0 | 11 | |
| GSE74703 | TAF5 | 6877 | 0 | 5 | 31 | |
| GSE74704 | TAF5 | 6877 | 1 | 4 | 15 | |
| TCGA | TAF5 | 6877 | 6 | 28 | 62 |
Total number of gains: 22; Total number of losses: 97; Total Number of normals: 369.
Somatic mutations of TAF5:
Generating mutation plots.
Highly correlated genes for TAF5:
Showing top 20/736 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF5 | FBXO5 | 0.744723 | 9 | 0 | 9 |
| TAF5 | SOX30 | 0.727565 | 3 | 0 | 3 |
| TAF5 | ZNF678 | 0.717092 | 3 | 0 | 3 |
| TAF5 | ZNF670 | 0.710494 | 4 | 0 | 4 |
| TAF5 | GMNN | 0.704263 | 11 | 0 | 10 |
| TAF5 | CENPL | 0.701465 | 6 | 0 | 6 |
| TAF5 | LIN9 | 0.693619 | 7 | 0 | 7 |
| TAF5 | DESI2 | 0.691168 | 9 | 0 | 9 |
| TAF5 | CENPN | 0.686229 | 10 | 0 | 10 |
| TAF5 | RAD51AP1 | 0.68585 | 12 | 0 | 11 |
| TAF5 | CDK1 | 0.683742 | 11 | 0 | 10 |
| TAF5 | CCDC34 | 0.683466 | 7 | 0 | 7 |
| TAF5 | ERCC6L | 0.682618 | 10 | 0 | 9 |
| TAF5 | CDC6 | 0.678619 | 9 | 0 | 9 |
| TAF5 | CENPF | 0.671719 | 10 | 0 | 10 |
| TAF5 | BIRC5 | 0.670546 | 8 | 0 | 8 |
| TAF5 | DSCC1 | 0.670371 | 9 | 0 | 8 |
| TAF5 | POC1A | 0.670188 | 6 | 0 | 6 |
| TAF5 | KIF15 | 0.66677 | 10 | 0 | 9 |
| TAF5 | CKS1B | 0.662819 | 11 | 0 | 9 |
For details and further investigation, click here
