OOEP

 

Full name: oocyte expressed protein Alias Symbol: Em:AC019205.2|KHDC2
Type: protein-coding gene Cytoband: 6q13
Entrez ID: 441161 HGNC ID: HGNC:21382 Ensembl Gene: ENSG00000203907 OMIM ID: 611689
Drug and gene relationship at DGIdb

 

Expression of OOEP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OOEP 441161 238218_at 0.1796 0.8517
GSE26886 OOEP 441161 238218_at 0.2967 0.3214
GSE45670 OOEP 441161 238218_at 0.0843 0.5384
GSE53622 OOEP 441161 19073 0.2650 0.0272
GSE53624 OOEP 441161 19073 0.1707 0.2354
GSE63941 OOEP 441161 238218_at 0.2383 0.3247
GSE77861 OOEP 441161 238218_at -0.0542 0.6925
TCGA OOEP 441161 RNAseq 0.3032 0.7753

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by OOEP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of OOEP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OOEP 441161 1 3 26
GSE20123 OOEP 441161 1 2 27
GSE43470 OOEP 441161 3 0 40
GSE46452 OOEP 441161 2 11 46
GSE47630 OOEP 441161 8 4 28
GSE54993 OOEP 441161 3 2 65
GSE54994 OOEP 441161 8 9 36
GSE60625 OOEP 441161 0 1 10
GSE74703 OOEP 441161 3 0 33
GSE74704 OOEP 441161 0 1 19
TCGA OOEP 441161 10 21 65

Total number of gains: 39; Total number of losses: 54; Total Number of normals: 395.  

 

Somatic mutations of OOEP:

 

Generating mutation plots.

 

Highly correlated genes for OOEP:

 

Showing all 18 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OOEPRPLP00.664151303
OOEPPARS20.656959303
OOEPMTOR0.65468303
OOEPFOXJ10.65209303
OOEPEXOSC10.64381303
OOEPRPP300.640725303
OOEPRITA10.634555303
OOEPZNRD10.615541303
OOEPLDLRAP10.608723303
OOEPDDX430.601537806
OOEPRPS180.597819303
OOEPZFAS10.584968303
OOEPANAPC50.58329403
OOEPDNPH10.57525503
OOEPBCL11A0.568297303
OOEPTRPM20.562255303
OOEPTRAP10.534339303
OOEPPRDX40.526451403

For details and further investigation, click here