| Full name: haptoglobin-related protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.2 | ||
| Entrez ID: 3250 | HGNC ID: HGNC:5156 | Ensembl Gene: ENSG00000261701 | OMIM ID: 140210 |
| Drug and gene relationship at DGIdb | |||
Expression of HPR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HPR | 3250 | 208471_at | -0.0268 | 0.9176 | |
| GSE20347 | HPR | 3250 | 208471_at | -0.0375 | 0.5252 | |
| GSE23400 | HPR | 3250 | 208471_at | -0.0254 | 0.2587 | |
| GSE26886 | HPR | 3250 | 208471_at | 0.0293 | 0.7817 | |
| GSE29001 | HPR | 3250 | 208471_at | 0.0566 | 0.6107 | |
| GSE38129 | HPR | 3250 | 208471_at | -0.0790 | 0.1360 | |
| GSE45670 | HPR | 3250 | 208471_at | -0.0303 | 0.7182 | |
| GSE63941 | HPR | 3250 | 208471_at | 0.0168 | 0.9383 | |
| GSE77861 | HPR | 3250 | 208471_at | 0.0280 | 0.8318 | |
| GSE97050 | HPR | 3250 | A_33_P3289236 | -0.0499 | 0.8956 | |
| TCGA | HPR | 3250 | RNAseq | -3.3952 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by HPR expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HPR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HPR | 3250 | 4 | 0 | 26 | |
| GSE20123 | HPR | 3250 | 4 | 0 | 26 | |
| GSE43470 | HPR | 3250 | 2 | 8 | 33 | |
| GSE46452 | HPR | 3250 | 38 | 2 | 19 | |
| GSE47630 | HPR | 3250 | 11 | 8 | 21 | |
| GSE54993 | HPR | 3250 | 2 | 4 | 64 | |
| GSE54994 | HPR | 3250 | 8 | 10 | 35 | |
| GSE60625 | HPR | 3250 | 4 | 0 | 7 | |
| GSE74703 | HPR | 3250 | 2 | 5 | 29 | |
| GSE74704 | HPR | 3250 | 2 | 0 | 18 | |
| TCGA | HPR | 3250 | 25 | 15 | 56 |
Total number of gains: 102; Total number of losses: 52; Total Number of normals: 334.
Somatic mutations of HPR:
Generating mutation plots.
Highly correlated genes for HPR:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HPR | SLCO1A2 | 0.767704 | 4 | 0 | 4 |
| HPR | NHLRC4 | 0.751508 | 3 | 0 | 3 |
| HPR | SLC5A11 | 0.723132 | 3 | 0 | 3 |
| HPR | RNF215 | 0.701356 | 4 | 0 | 3 |
| HPR | HAP1 | 0.669902 | 3 | 0 | 3 |
| HPR | GPRC5D | 0.646705 | 4 | 0 | 3 |
| HPR | FOXB1 | 0.645034 | 4 | 0 | 3 |
| HPR | OR12D3 | 0.639896 | 4 | 0 | 3 |
| HPR | CBLN4 | 0.629524 | 4 | 0 | 3 |
| HPR | LRIT1 | 0.622029 | 5 | 0 | 4 |
| HPR | GHRHR | 0.615925 | 4 | 0 | 3 |
| HPR | PSG6 | 0.611445 | 5 | 0 | 4 |
| HPR | DDX43 | 0.608701 | 4 | 0 | 3 |
| HPR | ADAMTS7 | 0.606363 | 5 | 0 | 3 |
| HPR | AGRP | 0.605098 | 4 | 0 | 3 |
| HPR | ATP2B2 | 0.604922 | 4 | 0 | 3 |
| HPR | EXOSC1 | 0.598135 | 5 | 0 | 3 |
| HPR | TRAPPC9 | 0.593548 | 5 | 0 | 3 |
| HPR | GATA4 | 0.591374 | 4 | 0 | 3 |
| HPR | HECW1 | 0.589435 | 5 | 0 | 3 |
For details and further investigation, click here
