| Full name: transketolase like 1 | Alias Symbol: TKR|TKT2 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 8277 | HGNC ID: HGNC:11835 | Ensembl Gene: ENSG00000007350 | OMIM ID: 300044 |
| Drug and gene relationship at DGIdb | |||
Expression of TKTL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TKTL1 | 8277 | 214183_s_at | 0.4879 | 0.9003 | |
| GSE20347 | TKTL1 | 8277 | 214183_s_at | -0.0387 | 0.6670 | |
| GSE23400 | TKTL1 | 8277 | 216370_s_at | -0.1597 | 0.0090 | |
| GSE26886 | TKTL1 | 8277 | 216370_s_at | 0.4178 | 0.3600 | |
| GSE29001 | TKTL1 | 8277 | 216370_s_at | -0.1214 | 0.4445 | |
| GSE38129 | TKTL1 | 8277 | 214183_s_at | -0.0602 | 0.6535 | |
| GSE45670 | TKTL1 | 8277 | 216370_s_at | -0.1262 | 0.2923 | |
| GSE53622 | TKTL1 | 8277 | 85907 | 0.0522 | 0.7694 | |
| GSE53624 | TKTL1 | 8277 | 85907 | 0.0826 | 0.6149 | |
| GSE63941 | TKTL1 | 8277 | 216370_s_at | -0.1391 | 0.3157 | |
| GSE77861 | TKTL1 | 8277 | 216370_s_at | 0.4192 | 0.3450 | |
| GSE97050 | TKTL1 | 8277 | A_23_P259901 | -0.0138 | 0.9625 | |
| TCGA | TKTL1 | 8277 | RNAseq | 1.8544 | 0.1433 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TKTL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TKTL1:
No record found for this gene.
Somatic mutations of TKTL1:
Generating mutation plots.
Highly correlated genes for TKTL1:
Showing top 20/50 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TKTL1 | GPAT2 | 0.882187 | 3 | 0 | 3 |
| TKTL1 | ZSWIM3 | 0.773435 | 3 | 0 | 3 |
| TKTL1 | DNAH6 | 0.762059 | 3 | 0 | 3 |
| TKTL1 | BAX | 0.73192 | 3 | 0 | 3 |
| TKTL1 | GPN2 | 0.729867 | 3 | 0 | 3 |
| TKTL1 | PPOX | 0.727141 | 4 | 0 | 3 |
| TKTL1 | BCL2L12 | 0.726225 | 3 | 0 | 3 |
| TKTL1 | APOL4 | 0.716965 | 3 | 0 | 3 |
| TKTL1 | SLCO1B1 | 0.703763 | 3 | 0 | 3 |
| TKTL1 | FAM189B | 0.694957 | 4 | 0 | 4 |
| TKTL1 | AIFM3 | 0.692249 | 4 | 0 | 3 |
| TKTL1 | RSPH1 | 0.684961 | 3 | 0 | 3 |
| TKTL1 | ZNF526 | 0.678122 | 5 | 0 | 4 |
| TKTL1 | LAMTOR2 | 0.669804 | 4 | 0 | 4 |
| TKTL1 | CLDN3 | 0.668897 | 3 | 0 | 3 |
| TKTL1 | HIF3A | 0.666332 | 3 | 0 | 3 |
| TKTL1 | AKR7A3 | 0.659215 | 4 | 0 | 3 |
| TKTL1 | IPO13 | 0.655698 | 4 | 0 | 3 |
| TKTL1 | CHP2 | 0.648692 | 4 | 0 | 3 |
| TKTL1 | ZNF777 | 0.640396 | 4 | 0 | 3 |
For details and further investigation, click here
