| Full name: forkhead box F1 | Alias Symbol: FREAC1 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 2294 | HGNC ID: HGNC:3809 | Ensembl Gene: ENSG00000103241 | OMIM ID: 601089 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FOXF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXF1 | 2294 | 205935_at | -1.4599 | 0.0889 | |
| GSE20347 | FOXF1 | 2294 | 205935_at | -0.3888 | 0.1992 | |
| GSE23400 | FOXF1 | 2294 | 205935_at | -0.4984 | 0.0022 | |
| GSE26886 | FOXF1 | 2294 | 205935_at | 0.4026 | 0.3016 | |
| GSE29001 | FOXF1 | 2294 | 205935_at | -0.6328 | 0.0954 | |
| GSE38129 | FOXF1 | 2294 | 205935_at | -0.9478 | 0.0077 | |
| GSE45670 | FOXF1 | 2294 | 205935_at | -2.1131 | 0.0000 | |
| GSE53622 | FOXF1 | 2294 | 98444 | -0.9282 | 0.0000 | |
| GSE53624 | FOXF1 | 2294 | 98444 | -0.7812 | 0.0000 | |
| GSE63941 | FOXF1 | 2294 | 205935_at | -6.4114 | 0.0000 | |
| GSE77861 | FOXF1 | 2294 | 205935_at | 0.5238 | 0.0577 | |
| GSE97050 | FOXF1 | 2294 | A_23_P118254 | -0.8938 | 0.1822 | |
| SRP007169 | FOXF1 | 2294 | RNAseq | 0.0385 | 0.9419 | |
| SRP064894 | FOXF1 | 2294 | RNAseq | -0.7613 | 0.0213 | |
| SRP133303 | FOXF1 | 2294 | RNAseq | -0.3390 | 0.3332 | |
| SRP159526 | FOXF1 | 2294 | RNAseq | -0.2704 | 0.5052 | |
| SRP193095 | FOXF1 | 2294 | RNAseq | 0.3493 | 0.4027 | |
| SRP219564 | FOXF1 | 2294 | RNAseq | 0.2106 | 0.8360 | |
| TCGA | FOXF1 | 2294 | RNAseq | -0.7615 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FOXF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXF1 | 2294 | 5 | 2 | 23 | |
| GSE20123 | FOXF1 | 2294 | 5 | 2 | 23 | |
| GSE43470 | FOXF1 | 2294 | 2 | 11 | 30 | |
| GSE46452 | FOXF1 | 2294 | 38 | 1 | 20 | |
| GSE47630 | FOXF1 | 2294 | 11 | 9 | 20 | |
| GSE54993 | FOXF1 | 2294 | 3 | 4 | 63 | |
| GSE54994 | FOXF1 | 2294 | 9 | 11 | 33 | |
| GSE60625 | FOXF1 | 2294 | 4 | 0 | 7 | |
| GSE74703 | FOXF1 | 2294 | 1 | 8 | 27 | |
| GSE74704 | FOXF1 | 2294 | 3 | 2 | 15 | |
| TCGA | FOXF1 | 2294 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 65; Total Number of normals: 315.
Somatic mutations of FOXF1:
Generating mutation plots.
Highly correlated genes for FOXF1:
Showing top 20/1195 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXF1 | AFF3 | 0.881191 | 3 | 0 | 3 |
| FOXF1 | FIBIN | 0.829102 | 5 | 0 | 5 |
| FOXF1 | MICU3 | 0.824529 | 5 | 0 | 5 |
| FOXF1 | TCEAL5 | 0.82351 | 3 | 0 | 3 |
| FOXF1 | RCAN2 | 0.822997 | 13 | 0 | 13 |
| FOXF1 | JAM3 | 0.821175 | 13 | 0 | 13 |
| FOXF1 | TMEM47 | 0.816711 | 13 | 0 | 13 |
| FOXF1 | C11orf96 | 0.810357 | 5 | 0 | 5 |
| FOXF1 | KCND3 | 0.803544 | 4 | 0 | 4 |
| FOXF1 | MRVI1 | 0.801935 | 8 | 0 | 8 |
| FOXF1 | CNN1 | 0.801261 | 11 | 0 | 11 |
| FOXF1 | MAGI2-AS3 | 0.799695 | 6 | 0 | 6 |
| FOXF1 | UBXN10 | 0.798304 | 3 | 0 | 3 |
| FOXF1 | MGARP | 0.796723 | 3 | 0 | 3 |
| FOXF1 | CYP4V2 | 0.795032 | 4 | 0 | 4 |
| FOXF1 | PREX2 | 0.793578 | 4 | 0 | 4 |
| FOXF1 | PDE5A | 0.789393 | 10 | 0 | 10 |
| FOXF1 | LINC01279 | 0.787132 | 4 | 0 | 4 |
| FOXF1 | ZCCHC24 | 0.787042 | 11 | 0 | 11 |
| FOXF1 | TCEAL6 | 0.779892 | 3 | 0 | 3 |
For details and further investigation, click here
