| Full name: fin bud initiation factor homolog | Alias Symbol: MGC24932 | ||
| Type: protein-coding gene | Cytoband: 11p14.2 | ||
| Entrez ID: 387758 | HGNC ID: HGNC:33747 | Ensembl Gene: ENSG00000176971 | OMIM ID: 617085 |
| Drug and gene relationship at DGIdb | |||
Expression of FIBIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FIBIN | 387758 | 226769_at | -1.6649 | 0.2056 | |
| GSE26886 | FIBIN | 387758 | 226769_at | 0.2405 | 0.6676 | |
| GSE45670 | FIBIN | 387758 | 226769_at | -2.5321 | 0.0000 | |
| GSE63941 | FIBIN | 387758 | 226769_at | -6.1867 | 0.0001 | |
| GSE77861 | FIBIN | 387758 | 226769_at | -0.1974 | 0.0298 | |
| GSE97050 | FIBIN | 387758 | A_33_P3325497 | -0.4442 | 0.4399 | |
| SRP007169 | FIBIN | 387758 | RNAseq | 2.9844 | 0.0000 | |
| SRP008496 | FIBIN | 387758 | RNAseq | 3.4530 | 0.0000 | |
| SRP064894 | FIBIN | 387758 | RNAseq | 0.3689 | 0.4321 | |
| SRP133303 | FIBIN | 387758 | RNAseq | 0.5340 | 0.1856 | |
| SRP159526 | FIBIN | 387758 | RNAseq | -0.6089 | 0.1036 | |
| SRP219564 | FIBIN | 387758 | RNAseq | -0.5340 | 0.5351 | |
| TCGA | FIBIN | 387758 | RNAseq | -0.2558 | 0.2215 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by FIBIN expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FIBIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FIBIN | 387758 | 1 | 9 | 20 | |
| GSE20123 | FIBIN | 387758 | 1 | 8 | 21 | |
| GSE43470 | FIBIN | 387758 | 1 | 5 | 37 | |
| GSE46452 | FIBIN | 387758 | 7 | 5 | 47 | |
| GSE47630 | FIBIN | 387758 | 3 | 10 | 27 | |
| GSE54993 | FIBIN | 387758 | 3 | 0 | 67 | |
| GSE54994 | FIBIN | 387758 | 4 | 11 | 38 | |
| GSE60625 | FIBIN | 387758 | 0 | 0 | 11 | |
| GSE74703 | FIBIN | 387758 | 1 | 3 | 32 | |
| GSE74704 | FIBIN | 387758 | 0 | 8 | 12 | |
| TCGA | FIBIN | 387758 | 12 | 24 | 60 |
Total number of gains: 33; Total number of losses: 83; Total Number of normals: 372.
Somatic mutations of FIBIN:
Generating mutation plots.
Highly correlated genes for FIBIN:
Showing top 20/953 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FIBIN | DIXDC1 | 0.900029 | 4 | 0 | 4 |
| FIBIN | ITGA1 | 0.880182 | 4 | 0 | 4 |
| FIBIN | DDR2 | 0.872522 | 5 | 0 | 5 |
| FIBIN | SVEP1 | 0.87184 | 4 | 0 | 4 |
| FIBIN | FGF7 | 0.871483 | 4 | 0 | 4 |
| FIBIN | RSPO3 | 0.868052 | 4 | 0 | 4 |
| FIBIN | C3orf70 | 0.865623 | 3 | 0 | 3 |
| FIBIN | MEOX2 | 0.862472 | 3 | 0 | 3 |
| FIBIN | COLEC12 | 0.859916 | 4 | 0 | 4 |
| FIBIN | CBX7 | 0.858818 | 3 | 0 | 3 |
| FIBIN | LRRN4CL | 0.85719 | 5 | 0 | 5 |
| FIBIN | FHL5 | 0.855347 | 3 | 0 | 3 |
| FIBIN | CXCL12 | 0.853378 | 5 | 0 | 5 |
| FIBIN | ZNF25 | 0.852726 | 4 | 0 | 4 |
| FIBIN | GFRA1 | 0.846696 | 4 | 0 | 4 |
| FIBIN | APOLD1 | 0.842354 | 3 | 0 | 3 |
| FIBIN | KLF2 | 0.839764 | 4 | 0 | 4 |
| FIBIN | DMD | 0.839521 | 3 | 0 | 3 |
| FIBIN | PAMR1 | 0.839038 | 4 | 0 | 4 |
| FIBIN | COL14A1 | 0.837805 | 4 | 0 | 4 |
For details and further investigation, click here
