| Full name: cytochrome P450 family 4 subfamily V member 2 | Alias Symbol: CYP4AH1 | ||
| Type: protein-coding gene | Cytoband: 4q35.1-q35.2 | ||
| Entrez ID: 285440 | HGNC ID: HGNC:23198 | Ensembl Gene: ENSG00000145476 | OMIM ID: 608614 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP4V2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP4V2 | 285440 | 226745_at | -0.7039 | 0.2276 | |
| GSE26886 | CYP4V2 | 285440 | 229959_at | -0.0072 | 0.9615 | |
| GSE45670 | CYP4V2 | 285440 | 228391_at | -1.0901 | 0.0003 | |
| GSE63941 | CYP4V2 | 285440 | 226745_at | -2.1318 | 0.0014 | |
| GSE77861 | CYP4V2 | 285440 | 229959_at | -0.0817 | 0.4945 | |
| GSE97050 | CYP4V2 | 285440 | A_24_P945228 | -0.6269 | 0.1860 | |
| SRP007169 | CYP4V2 | 285440 | RNAseq | 0.7518 | 0.2655 | |
| SRP008496 | CYP4V2 | 285440 | RNAseq | 0.6666 | 0.1847 | |
| SRP064894 | CYP4V2 | 285440 | RNAseq | -0.3317 | 0.1463 | |
| SRP133303 | CYP4V2 | 285440 | RNAseq | -0.1864 | 0.4053 | |
| SRP159526 | CYP4V2 | 285440 | RNAseq | 0.0147 | 0.9754 | |
| SRP193095 | CYP4V2 | 285440 | RNAseq | -0.2200 | 0.2143 | |
| SRP219564 | CYP4V2 | 285440 | RNAseq | -0.1243 | 0.8169 | |
| TCGA | CYP4V2 | 285440 | RNAseq | -0.3687 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CYP4V2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CYP4V2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP4V2 | 285440 | 2 | 11 | 17 | |
| GSE20123 | CYP4V2 | 285440 | 2 | 11 | 17 | |
| GSE43470 | CYP4V2 | 285440 | 1 | 14 | 28 | |
| GSE46452 | CYP4V2 | 285440 | 1 | 36 | 22 | |
| GSE47630 | CYP4V2 | 285440 | 0 | 22 | 18 | |
| GSE54993 | CYP4V2 | 285440 | 10 | 0 | 60 | |
| GSE54994 | CYP4V2 | 285440 | 3 | 12 | 38 | |
| GSE60625 | CYP4V2 | 285440 | 0 | 0 | 11 | |
| GSE74703 | CYP4V2 | 285440 | 1 | 11 | 24 | |
| GSE74704 | CYP4V2 | 285440 | 1 | 5 | 14 | |
| TCGA | CYP4V2 | 285440 | 10 | 34 | 52 |
Total number of gains: 31; Total number of losses: 156; Total Number of normals: 301.
Somatic mutations of CYP4V2:
Generating mutation plots.
Highly correlated genes for CYP4V2:
Showing top 20/588 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP4V2 | CYYR1 | 0.840392 | 3 | 0 | 3 |
| CYP4V2 | C7 | 0.837938 | 3 | 0 | 3 |
| CYP4V2 | PTPRM | 0.829434 | 3 | 0 | 3 |
| CYP4V2 | FILIP1L | 0.825309 | 3 | 0 | 3 |
| CYP4V2 | EBF3 | 0.823822 | 3 | 0 | 3 |
| CYP4V2 | ACSS3 | 0.821307 | 3 | 0 | 3 |
| CYP4V2 | THYN1 | 0.820405 | 3 | 0 | 3 |
| CYP4V2 | GYPC | 0.82023 | 4 | 0 | 4 |
| CYP4V2 | APOD | 0.815774 | 3 | 0 | 3 |
| CYP4V2 | TXNIP | 0.813769 | 3 | 0 | 3 |
| CYP4V2 | FGF7 | 0.810017 | 4 | 0 | 4 |
| CYP4V2 | CASQ2 | 0.809342 | 3 | 0 | 3 |
| CYP4V2 | FNBP1 | 0.808399 | 4 | 0 | 4 |
| CYP4V2 | S1PR3 | 0.803474 | 3 | 0 | 3 |
| CYP4V2 | CUL4B | 0.800672 | 3 | 0 | 3 |
| CYP4V2 | ITGA9 | 0.799469 | 3 | 0 | 3 |
| CYP4V2 | EMCN | 0.798863 | 3 | 0 | 3 |
| CYP4V2 | COL15A1 | 0.797946 | 3 | 0 | 3 |
| CYP4V2 | ASPA | 0.797694 | 4 | 0 | 4 |
| CYP4V2 | FOXF1 | 0.795032 | 4 | 0 | 4 |
For details and further investigation, click here
