FSCB

 

Full name: fibrous sheath CABYR binding protein Alias Symbol: DKFZP434F1017
Type: protein-coding gene Cytoband: 14q21.2
Entrez ID: 84075 HGNC ID: HGNC:20494 Ensembl Gene: ENSG00000189139 OMIM ID: 611779
Drug and gene relationship at DGIdb

 

Expression of FSCB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FSCB 84075 224274_at 0.0325 0.9105
GSE26886 FSCB 84075 224274_at 0.1087 0.2321
GSE45670 FSCB 84075 224274_at 0.0976 0.1950
GSE53622 FSCB 84075 53254 0.1384 0.4313
GSE53624 FSCB 84075 53254 0.1682 0.2142
GSE63941 FSCB 84075 224274_at 0.0150 0.9249
GSE77861 FSCB 84075 224274_at -0.0033 0.9684
TCGA FSCB 84075 RNAseq 0.7287 0.6814

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by FSCB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FSCB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FSCB 84075 6 5 19
GSE20123 FSCB 84075 6 5 19
GSE43470 FSCB 84075 8 3 32
GSE46452 FSCB 84075 18 2 39
GSE47630 FSCB 84075 11 10 19
GSE54993 FSCB 84075 3 9 58
GSE54994 FSCB 84075 18 5 30
GSE60625 FSCB 84075 0 2 9
GSE74703 FSCB 84075 7 3 26
GSE74704 FSCB 84075 3 3 14
TCGA FSCB 84075 32 13 51

Total number of gains: 112; Total number of losses: 60; Total Number of normals: 316.  

 

Somatic mutations of FSCB:

 

Generating mutation plots.

 

Highly correlated genes for FSCB:

 

Showing all 16 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FSCBPCAT40.623404403
FSCBSLITRK20.619371403
FSCBTAL20.607932303
FSCBMYL100.597487403
FSCBCACNA1F0.593616303
FSCBDLL40.590941403
FSCBFBXO390.581095303
FSCBPRORY0.578423303
FSCBSNORA71A0.567428303
FSCBKCNQ1DN0.566777503
FSCBTUBB30.55942403
FSCBSPATA240.556785404
FSCBKLHL340.545239503
FSCBDHH0.54332403
FSCBSLC12A10.533049403
FSCBFKBP60.526943403

For details and further investigation, click here