| Full name: F-box protein 39 | Alias Symbol: MGC35179|Fbx39|CT144 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 162517 | HGNC ID: HGNC:28565 | Ensembl Gene: ENSG00000177294 | OMIM ID: 609106 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO39:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO39 | 162517 | 1552830_at | 0.0417 | 0.8543 | |
| GSE26886 | FBXO39 | 162517 | 1552830_at | 0.1448 | 0.1754 | |
| GSE45670 | FBXO39 | 162517 | 1552830_at | 0.1524 | 0.0499 | |
| GSE53622 | FBXO39 | 162517 | 13509 | 0.2025 | 0.1088 | |
| GSE53624 | FBXO39 | 162517 | 13509 | -0.0628 | 0.6675 | |
| GSE63941 | FBXO39 | 162517 | 1552830_at | 0.0525 | 0.6614 | |
| GSE77861 | FBXO39 | 162517 | 1552830_at | 0.0485 | 0.5958 | |
| GSE97050 | FBXO39 | 162517 | A_32_P204980 | 0.0402 | 0.8915 | |
| SRP219564 | FBXO39 | 162517 | RNAseq | 0.9890 | 0.1649 | |
| TCGA | FBXO39 | 162517 | RNAseq | 2.2544 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FBXO39 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO39:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO39 | 162517 | 4 | 2 | 24 | |
| GSE20123 | FBXO39 | 162517 | 4 | 3 | 23 | |
| GSE43470 | FBXO39 | 162517 | 1 | 6 | 36 | |
| GSE46452 | FBXO39 | 162517 | 34 | 1 | 24 | |
| GSE47630 | FBXO39 | 162517 | 7 | 1 | 32 | |
| GSE54993 | FBXO39 | 162517 | 4 | 3 | 63 | |
| GSE54994 | FBXO39 | 162517 | 5 | 8 | 40 | |
| GSE60625 | FBXO39 | 162517 | 4 | 0 | 7 | |
| GSE74703 | FBXO39 | 162517 | 1 | 3 | 32 | |
| GSE74704 | FBXO39 | 162517 | 2 | 1 | 17 | |
| TCGA | FBXO39 | 162517 | 19 | 20 | 57 |
Total number of gains: 85; Total number of losses: 48; Total Number of normals: 355.
Somatic mutations of FBXO39:
Generating mutation plots.
Highly correlated genes for FBXO39:
Showing top 20/96 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO39 | MKNK1 | 0.765977 | 3 | 0 | 3 |
| FBXO39 | DNMBP | 0.732807 | 3 | 0 | 3 |
| FBXO39 | THAP11 | 0.730142 | 3 | 0 | 3 |
| FBXO39 | FAM32A | 0.724598 | 3 | 0 | 3 |
| FBXO39 | SLC45A4 | 0.72142 | 3 | 0 | 3 |
| FBXO39 | TMEM208 | 0.719789 | 4 | 0 | 3 |
| FBXO39 | GSC2 | 0.705238 | 3 | 0 | 3 |
| FBXO39 | ATP6V1E1 | 0.699053 | 3 | 0 | 3 |
| FBXO39 | NUP205 | 0.698663 | 3 | 0 | 3 |
| FBXO39 | FGF16 | 0.695366 | 3 | 0 | 3 |
| FBXO39 | ANXA7 | 0.693573 | 3 | 0 | 3 |
| FBXO39 | RNF7 | 0.693445 | 3 | 0 | 3 |
| FBXO39 | RAB11FIP5 | 0.69243 | 3 | 0 | 3 |
| FBXO39 | TBC1D2 | 0.691508 | 3 | 0 | 3 |
| FBXO39 | HRH1 | 0.691135 | 4 | 0 | 4 |
| FBXO39 | RNF181 | 0.68958 | 3 | 0 | 3 |
| FBXO39 | PCBP3 | 0.683906 | 3 | 0 | 3 |
| FBXO39 | IDH3A | 0.677009 | 4 | 0 | 3 |
| FBXO39 | NRBF2 | 0.676935 | 3 | 0 | 3 |
| FBXO39 | F2RL1 | 0.675452 | 3 | 0 | 3 |
For details and further investigation, click here
