| Full name: FKBP prolyl isomerase 6 | Alias Symbol: PPIase|FKBP36 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 8468 | HGNC ID: HGNC:3722 | Ensembl Gene: ENSG00000077800 | OMIM ID: 604839 |
| Drug and gene relationship at DGIdb | |||
Expression of FKBP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKBP6 | 8468 | 206763_at | -0.0736 | 0.8174 | |
| GSE20347 | FKBP6 | 8468 | 206763_at | -0.1013 | 0.2183 | |
| GSE23400 | FKBP6 | 8468 | 206763_at | -0.0727 | 0.0373 | |
| GSE26886 | FKBP6 | 8468 | 206763_at | 0.1488 | 0.2368 | |
| GSE29001 | FKBP6 | 8468 | 206763_at | -0.1603 | 0.3108 | |
| GSE38129 | FKBP6 | 8468 | 206763_at | -0.1711 | 0.0324 | |
| GSE45670 | FKBP6 | 8468 | 206763_at | -0.0592 | 0.6849 | |
| GSE53622 | FKBP6 | 8468 | 147498 | -0.0265 | 0.7887 | |
| GSE53624 | FKBP6 | 8468 | 147498 | 0.1963 | 0.0084 | |
| GSE63941 | FKBP6 | 8468 | 206763_at | 0.2514 | 0.0744 | |
| GSE77861 | FKBP6 | 8468 | 206763_at | 0.0070 | 0.9748 | |
| TCGA | FKBP6 | 8468 | RNAseq | 2.1852 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FKBP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKBP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKBP6 | 8468 | 12 | 1 | 17 | |
| GSE20123 | FKBP6 | 8468 | 11 | 1 | 18 | |
| GSE43470 | FKBP6 | 8468 | 3 | 2 | 38 | |
| GSE46452 | FKBP6 | 8468 | 12 | 0 | 47 | |
| GSE47630 | FKBP6 | 8468 | 7 | 2 | 31 | |
| GSE54993 | FKBP6 | 8468 | 2 | 7 | 61 | |
| GSE54994 | FKBP6 | 8468 | 13 | 3 | 37 | |
| GSE60625 | FKBP6 | 8468 | 0 | 0 | 11 | |
| GSE74703 | FKBP6 | 8468 | 3 | 1 | 32 | |
| GSE74704 | FKBP6 | 8468 | 7 | 1 | 12 | |
| TCGA | FKBP6 | 8468 | 45 | 7 | 44 |
Total number of gains: 115; Total number of losses: 25; Total Number of normals: 348.
Somatic mutations of FKBP6:
Generating mutation plots.
Highly correlated genes for FKBP6:
Showing top 20/550 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKBP6 | ARMC5 | 0.713149 | 3 | 0 | 3 |
| FKBP6 | LIPF | 0.701241 | 3 | 0 | 3 |
| FKBP6 | FGF18 | 0.68621 | 4 | 0 | 3 |
| FKBP6 | SIK1 | 0.681129 | 5 | 0 | 5 |
| FKBP6 | CITED1 | 0.669821 | 3 | 0 | 3 |
| FKBP6 | CHD2 | 0.66625 | 3 | 0 | 3 |
| FKBP6 | CHD5 | 0.657346 | 4 | 0 | 3 |
| FKBP6 | CPNE6 | 0.656079 | 5 | 0 | 4 |
| FKBP6 | CYP2C19 | 0.654124 | 4 | 0 | 4 |
| FKBP6 | FGB | 0.653228 | 6 | 0 | 6 |
| FKBP6 | GRM7 | 0.651215 | 4 | 0 | 3 |
| FKBP6 | PCSK4 | 0.644757 | 3 | 0 | 3 |
| FKBP6 | LINC00598 | 0.644118 | 4 | 0 | 3 |
| FKBP6 | FOXN3-AS2 | 0.643169 | 4 | 0 | 4 |
| FKBP6 | MYBL1 | 0.643111 | 3 | 0 | 3 |
| FKBP6 | SLC6A11 | 0.642803 | 4 | 0 | 4 |
| FKBP6 | IGH | 0.642338 | 7 | 0 | 6 |
| FKBP6 | MUC13 | 0.640269 | 4 | 0 | 4 |
| FKBP6 | GNAT1 | 0.639957 | 6 | 0 | 5 |
| FKBP6 | CYP3A4 | 0.638769 | 3 | 0 | 3 |
For details and further investigation, click here
