| Full name: frizzled class receptor 9 | Alias Symbol: FZD3|CD349 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 8326 | HGNC ID: HGNC:4047 | Ensembl Gene: ENSG00000188763 | OMIM ID: 601766 |
| Drug and gene relationship at DGIdb | |||
FZD9 involved pathways:
Expression of FZD9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FZD9 | 8326 | 207639_at | 0.3242 | 0.1787 | |
| GSE20347 | FZD9 | 8326 | 207639_at | 0.0992 | 0.3081 | |
| GSE23400 | FZD9 | 8326 | 207639_at | -0.0329 | 0.4397 | |
| GSE26886 | FZD9 | 8326 | 207639_at | 0.4733 | 0.0017 | |
| GSE29001 | FZD9 | 8326 | 207639_at | 0.1554 | 0.1964 | |
| GSE38129 | FZD9 | 8326 | 207639_at | 0.1611 | 0.1454 | |
| GSE45670 | FZD9 | 8326 | 207639_at | 0.2502 | 0.0056 | |
| GSE53622 | FZD9 | 8326 | 53789 | -0.0302 | 0.6975 | |
| GSE53624 | FZD9 | 8326 | 53789 | 0.0144 | 0.8680 | |
| GSE63941 | FZD9 | 8326 | 207639_at | 0.1020 | 0.6699 | |
| GSE77861 | FZD9 | 8326 | 207639_at | 0.0705 | 0.5987 | |
| GSE97050 | FZD9 | 8326 | A_23_P59613 | -0.2966 | 0.2172 | |
| SRP159526 | FZD9 | 8326 | RNAseq | 2.7907 | 0.0001 | |
| TCGA | FZD9 | 8326 | RNAseq | 0.9802 | 0.0009 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FZD9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FZD9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FZD9 | 8326 | 12 | 1 | 17 | |
| GSE20123 | FZD9 | 8326 | 11 | 1 | 18 | |
| GSE43470 | FZD9 | 8326 | 3 | 2 | 38 | |
| GSE46452 | FZD9 | 8326 | 12 | 0 | 47 | |
| GSE47630 | FZD9 | 8326 | 7 | 2 | 31 | |
| GSE54993 | FZD9 | 8326 | 2 | 7 | 61 | |
| GSE54994 | FZD9 | 8326 | 13 | 3 | 37 | |
| GSE60625 | FZD9 | 8326 | 0 | 0 | 11 | |
| GSE74703 | FZD9 | 8326 | 3 | 1 | 32 | |
| GSE74704 | FZD9 | 8326 | 7 | 1 | 12 | |
| TCGA | FZD9 | 8326 | 45 | 7 | 44 |
Total number of gains: 115; Total number of losses: 25; Total Number of normals: 348.
Somatic mutations of FZD9:
Generating mutation plots.
Highly correlated genes for FZD9:
Showing top 20/690 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FZD9 | SLC22A31 | 0.849134 | 3 | 0 | 3 |
| FZD9 | YY2 | 0.845892 | 3 | 0 | 3 |
| FZD9 | DCDC1 | 0.83906 | 3 | 0 | 3 |
| FZD9 | CELF5 | 0.835224 | 3 | 0 | 3 |
| FZD9 | STRC | 0.834097 | 3 | 0 | 3 |
| FZD9 | KCP | 0.827843 | 3 | 0 | 3 |
| FZD9 | PLA2G2C | 0.816161 | 3 | 0 | 3 |
| FZD9 | GDF7 | 0.807789 | 3 | 0 | 3 |
| FZD9 | KRTAP4-8 | 0.798165 | 3 | 0 | 3 |
| FZD9 | C1QL2 | 0.795521 | 3 | 0 | 3 |
| FZD9 | MRGPRG | 0.792384 | 3 | 0 | 3 |
| FZD9 | ANKRD33B | 0.788276 | 3 | 0 | 3 |
| FZD9 | OR2T27 | 0.783853 | 3 | 0 | 3 |
| FZD9 | PRSS38 | 0.783784 | 3 | 0 | 3 |
| FZD9 | OR10AD1 | 0.779818 | 3 | 0 | 3 |
| FZD9 | ZNF527 | 0.779068 | 4 | 0 | 4 |
| FZD9 | BBC3 | 0.778359 | 3 | 0 | 3 |
| FZD9 | TMEM235 | 0.773334 | 3 | 0 | 3 |
| FZD9 | PRODH2 | 0.769302 | 3 | 0 | 3 |
| FZD9 | DEFB121 | 0.767283 | 3 | 0 | 3 |
For details and further investigation, click here
