GNAT1

 

Full name: G protein subunit alpha transducin 1 Alias Symbol: CSNBAD3
Type: protein-coding gene Cytoband: 3p21.31
Entrez ID: 2779 HGNC ID: HGNC:4393 Ensembl Gene: ENSG00000114349 OMIM ID: 139330
Drug and gene relationship at DGIdb

 

Expression of GNAT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GNAT1 2779 214286_at 0.0531 0.8684
GSE20347 GNAT1 2779 214286_at 0.0163 0.8712
GSE23400 GNAT1 2779 214286_at -0.1126 0.0040
GSE26886 GNAT1 2779 207514_s_at 0.1677 0.1964
GSE29001 GNAT1 2779 207514_s_at -0.1852 0.0789
GSE38129 GNAT1 2779 214286_at -0.0495 0.6917
GSE45670 GNAT1 2779 214286_at 0.1322 0.1555
GSE53622 GNAT1 2779 92878 -0.3790 0.0034
GSE53624 GNAT1 2779 92878 -0.0834 0.4383
GSE63941 GNAT1 2779 214286_at 0.1136 0.4015
GSE77861 GNAT1 2779 207514_s_at -0.0258 0.8345
SRP133303 GNAT1 2779 RNAseq -0.0127 0.9260
SRP159526 GNAT1 2779 RNAseq 0.2223 0.7516
SRP193095 GNAT1 2779 RNAseq -0.1663 0.2684
SRP219564 GNAT1 2779 RNAseq -0.1523 0.7611
TCGA GNAT1 2779 RNAseq 0.5533 0.5870

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GNAT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GNAT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GNAT1 2779 0 18 12
GSE20123 GNAT1 2779 0 19 11
GSE43470 GNAT1 2779 0 19 24
GSE46452 GNAT1 2779 2 16 41
GSE47630 GNAT1 2779 1 24 15
GSE54993 GNAT1 2779 6 2 62
GSE54994 GNAT1 2779 1 33 19
GSE60625 GNAT1 2779 5 0 6
GSE74703 GNAT1 2779 0 15 21
GSE74704 GNAT1 2779 0 12 8
TCGA GNAT1 2779 0 78 18

Total number of gains: 15; Total number of losses: 236; Total Number of normals: 237.  


 

Somatic mutations of GNAT1:

 

Generating mutation plots.

 

Highly correlated genes for GNAT1:

 

Showing top 20/1029 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GNAT1CDHR50.744499303
GNAT1KSR10.74045404
GNAT1NRG10.737981404
GNAT1ITGB30.719152404
GNAT1ZNF7710.716841303
GNAT1ELFN10.715398303
GNAT1SLC39A50.703481303
GNAT1RBBP8NL0.700445403
GNAT1KRT760.687436404
GNAT1PRR340.686911505
GNAT1AMN0.685486707
GNAT1VCX20.684488605
GNAT1TREML10.680534303
GNAT1EPOR0.679563605
GNAT1RPRML0.67526303
GNAT1PHLDB10.674958504
GNAT1SLC45A20.673864505
GNAT1LUZP40.671721404
GNAT1DLGAP30.669308404
GNAT1ART10.668976605

For details and further investigation, click here