| Full name: extracellular leucine rich repeat and fibronectin type III domain containing 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p22.3 | ||
| Entrez ID: 392617 | HGNC ID: HGNC:33154 | Ensembl Gene: ENSG00000225968 | OMIM ID: 614964 |
| Drug and gene relationship at DGIdb | |||
Expression of ELFN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELFN1 | 392617 | 229581_at | 0.2000 | 0.5492 | |
| GSE26886 | ELFN1 | 392617 | 229581_at | 0.6810 | 0.0000 | |
| GSE45670 | ELFN1 | 392617 | 229581_at | 0.1070 | 0.6251 | |
| GSE53622 | ELFN1 | 392617 | 16084 | 0.1499 | 0.0080 | |
| GSE53624 | ELFN1 | 392617 | 16084 | 0.1751 | 0.0086 | |
| GSE63941 | ELFN1 | 392617 | 229581_at | 0.1364 | 0.7638 | |
| GSE77861 | ELFN1 | 392617 | 229581_at | -0.0650 | 0.8028 | |
| GSE97050 | ELFN1 | 392617 | A_33_P3210848 | -0.0121 | 0.9721 | |
| SRP007169 | ELFN1 | 392617 | RNAseq | 2.0624 | 0.0052 | |
| SRP064894 | ELFN1 | 392617 | RNAseq | 1.4121 | 0.0000 | |
| SRP133303 | ELFN1 | 392617 | RNAseq | 1.2828 | 0.0012 | |
| SRP159526 | ELFN1 | 392617 | RNAseq | 2.3936 | 0.0001 | |
| SRP219564 | ELFN1 | 392617 | RNAseq | 0.5727 | 0.2694 | |
| TCGA | ELFN1 | 392617 | RNAseq | 0.4824 | 0.0105 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ELFN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELFN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELFN1 | 392617 | 14 | 0 | 16 | |
| GSE20123 | ELFN1 | 392617 | 14 | 0 | 16 | |
| GSE43470 | ELFN1 | 392617 | 6 | 2 | 35 | |
| GSE46452 | ELFN1 | 392617 | 13 | 1 | 45 | |
| GSE47630 | ELFN1 | 392617 | 10 | 1 | 29 | |
| GSE54993 | ELFN1 | 392617 | 0 | 7 | 63 | |
| GSE54994 | ELFN1 | 392617 | 19 | 2 | 32 | |
| GSE60625 | ELFN1 | 392617 | 0 | 0 | 11 | |
| GSE74703 | ELFN1 | 392617 | 6 | 1 | 29 | |
| GSE74704 | ELFN1 | 392617 | 9 | 0 | 11 | |
| TCGA | ELFN1 | 392617 | 57 | 5 | 34 |
Total number of gains: 148; Total number of losses: 19; Total Number of normals: 321.
Somatic mutations of ELFN1:
Generating mutation plots.
Highly correlated genes for ELFN1:
Showing top 20/327 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELFN1 | PLEKHA4 | 0.866292 | 3 | 0 | 3 |
| ELFN1 | SLC39A3 | 0.825369 | 3 | 0 | 3 |
| ELFN1 | ZNF771 | 0.79516 | 3 | 0 | 3 |
| ELFN1 | TMEM63B | 0.782669 | 3 | 0 | 3 |
| ELFN1 | RFNG | 0.772536 | 3 | 0 | 3 |
| ELFN1 | OR2T12 | 0.764341 | 3 | 0 | 3 |
| ELFN1 | VSTM4 | 0.757677 | 3 | 0 | 3 |
| ELFN1 | CALY | 0.750975 | 3 | 0 | 3 |
| ELFN1 | RNF187 | 0.742796 | 3 | 0 | 3 |
| ELFN1 | HAS3 | 0.741901 | 3 | 0 | 3 |
| ELFN1 | KRTAP21-2 | 0.741138 | 3 | 0 | 3 |
| ELFN1 | SFTPA2 | 0.73964 | 3 | 0 | 3 |
| ELFN1 | CCNB3 | 0.737594 | 3 | 0 | 3 |
| ELFN1 | VWA1 | 0.737316 | 3 | 0 | 3 |
| ELFN1 | SLC13A2 | 0.736745 | 4 | 0 | 4 |
| ELFN1 | KDM6B | 0.736364 | 3 | 0 | 3 |
| ELFN1 | CSF2 | 0.735709 | 3 | 0 | 3 |
| ELFN1 | ENTPD2 | 0.733521 | 5 | 0 | 4 |
| ELFN1 | ADAMTSL5 | 0.73149 | 5 | 0 | 5 |
| ELFN1 | OR2T33 | 0.729127 | 3 | 0 | 3 |
For details and further investigation, click here
