| Full name: DLG associated protein 3 | Alias Symbol: SAPAP3|DAP3 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 58512 | HGNC ID: HGNC:30368 | Ensembl Gene: ENSG00000116544 | OMIM ID: 611413 |
| Drug and gene relationship at DGIdb | |||
Expression of DLGAP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLGAP3 | 58512 | 231151_at | 0.0458 | 0.8618 | |
| GSE26886 | DLGAP3 | 58512 | 231151_at | 0.1389 | 0.2392 | |
| GSE45670 | DLGAP3 | 58512 | 231151_at | 0.0291 | 0.7290 | |
| GSE53622 | DLGAP3 | 58512 | 104504 | -0.1250 | 0.0511 | |
| GSE53624 | DLGAP3 | 58512 | 104504 | -0.5509 | 0.0000 | |
| GSE63941 | DLGAP3 | 58512 | 231151_at | 0.2567 | 0.0328 | |
| GSE77861 | DLGAP3 | 58512 | 231151_at | -0.1226 | 0.3752 | |
| GSE97050 | DLGAP3 | 58512 | A_33_P3232557 | 0.1295 | 0.5882 | |
| SRP133303 | DLGAP3 | 58512 | RNAseq | -0.0379 | 0.8777 | |
| SRP159526 | DLGAP3 | 58512 | RNAseq | 1.6233 | 0.0109 | |
| SRP219564 | DLGAP3 | 58512 | RNAseq | 1.2906 | 0.0700 | |
| TCGA | DLGAP3 | 58512 | RNAseq | 0.8945 | 0.0011 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DLGAP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLGAP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLGAP3 | 58512 | 2 | 5 | 23 | |
| GSE20123 | DLGAP3 | 58512 | 2 | 4 | 24 | |
| GSE43470 | DLGAP3 | 58512 | 6 | 2 | 35 | |
| GSE46452 | DLGAP3 | 58512 | 4 | 1 | 54 | |
| GSE47630 | DLGAP3 | 58512 | 8 | 3 | 29 | |
| GSE54993 | DLGAP3 | 58512 | 1 | 1 | 68 | |
| GSE54994 | DLGAP3 | 58512 | 11 | 2 | 40 | |
| GSE60625 | DLGAP3 | 58512 | 0 | 0 | 11 | |
| GSE74703 | DLGAP3 | 58512 | 5 | 1 | 30 | |
| GSE74704 | DLGAP3 | 58512 | 1 | 0 | 19 | |
| TCGA | DLGAP3 | 58512 | 13 | 18 | 65 |
Total number of gains: 53; Total number of losses: 37; Total Number of normals: 398.
Somatic mutations of DLGAP3:
Generating mutation plots.
Highly correlated genes for DLGAP3:
Showing top 20/333 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLGAP3 | ADAM30 | 0.720392 | 3 | 0 | 3 |
| DLGAP3 | SUGP1 | 0.700986 | 3 | 0 | 3 |
| DLGAP3 | SRL | 0.700635 | 3 | 0 | 3 |
| DLGAP3 | TMEM255B | 0.693938 | 3 | 0 | 3 |
| DLGAP3 | KLK4 | 0.691022 | 3 | 0 | 3 |
| DLGAP3 | KBTBD13 | 0.68936 | 3 | 0 | 3 |
| DLGAP3 | GJA3 | 0.689045 | 3 | 0 | 3 |
| DLGAP3 | MROH2A | 0.672913 | 4 | 0 | 3 |
| DLGAP3 | GNAT1 | 0.669308 | 4 | 0 | 4 |
| DLGAP3 | FASLG | 0.662147 | 3 | 0 | 3 |
| DLGAP3 | NPEPL1 | 0.659847 | 4 | 0 | 4 |
| DLGAP3 | SLC2A4RG | 0.659253 | 3 | 0 | 3 |
| DLGAP3 | CDIP1 | 0.649797 | 3 | 0 | 3 |
| DLGAP3 | CACNA1G-AS1 | 0.646704 | 3 | 0 | 3 |
| DLGAP3 | THEM5 | 0.646497 | 3 | 0 | 3 |
| DLGAP3 | CNIH2 | 0.645 | 6 | 0 | 5 |
| DLGAP3 | GPR152 | 0.643563 | 3 | 0 | 3 |
| DLGAP3 | CAPN13 | 0.641241 | 3 | 0 | 3 |
| DLGAP3 | IL34 | 0.638054 | 4 | 0 | 3 |
| DLGAP3 | WFIKKN1 | 0.634406 | 3 | 0 | 3 |
For details and further investigation, click here
