| Full name: keratin 76 | Alias Symbol: HUMCYT2A|KRT2B|KRT2P | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 51350 | HGNC ID: HGNC:24430 | Ensembl Gene: ENSG00000185069 | OMIM ID: 616671 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT76:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT76 | 51350 | 207878_at | -0.4345 | 0.2400 | |
| GSE20347 | KRT76 | 51350 | 207878_at | -0.0612 | 0.6368 | |
| GSE23400 | KRT76 | 51350 | 207878_at | -0.1768 | 0.0030 | |
| GSE26886 | KRT76 | 51350 | 207878_at | -0.1545 | 0.1339 | |
| GSE29001 | KRT76 | 51350 | 207878_at | -0.2061 | 0.2157 | |
| GSE38129 | KRT76 | 51350 | 207878_at | -0.2251 | 0.1020 | |
| GSE45670 | KRT76 | 51350 | 207878_at | 0.2241 | 0.5420 | |
| GSE53622 | KRT76 | 51350 | 22452 | -0.5475 | 0.0023 | |
| GSE53624 | KRT76 | 51350 | 22452 | -1.1967 | 0.0000 | |
| GSE63941 | KRT76 | 51350 | 207878_at | 0.2207 | 0.2009 | |
| GSE77861 | KRT76 | 51350 | 207878_at | -0.4406 | 0.0147 | |
| TCGA | KRT76 | 51350 | RNAseq | 1.4959 | 0.2895 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KRT76 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT76:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT76 | 51350 | 8 | 1 | 21 | |
| GSE20123 | KRT76 | 51350 | 8 | 1 | 21 | |
| GSE43470 | KRT76 | 51350 | 3 | 0 | 40 | |
| GSE46452 | KRT76 | 51350 | 7 | 1 | 51 | |
| GSE47630 | KRT76 | 51350 | 10 | 2 | 28 | |
| GSE54993 | KRT76 | 51350 | 0 | 5 | 65 | |
| GSE54994 | KRT76 | 51350 | 4 | 1 | 48 | |
| GSE60625 | KRT76 | 51350 | 0 | 0 | 11 | |
| GSE74703 | KRT76 | 51350 | 3 | 0 | 33 | |
| GSE74704 | KRT76 | 51350 | 5 | 1 | 14 | |
| TCGA | KRT76 | 51350 | 13 | 11 | 72 |
Total number of gains: 61; Total number of losses: 23; Total Number of normals: 404.
Somatic mutations of KRT76:
Generating mutation plots.
Highly correlated genes for KRT76:
Showing top 20/991 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT76 | KLF15 | 0.78062 | 4 | 0 | 4 |
| KRT76 | CCZ1 | 0.765146 | 4 | 0 | 4 |
| KRT76 | KIR2DS5 | 0.761815 | 4 | 0 | 4 |
| KRT76 | NXPE4 | 0.753357 | 4 | 0 | 4 |
| KRT76 | CHRM2 | 0.747983 | 4 | 0 | 4 |
| KRT76 | GNRHR | 0.731274 | 4 | 0 | 4 |
| KRT76 | HRH2 | 0.729414 | 4 | 0 | 4 |
| KRT76 | SLC5A7 | 0.727828 | 4 | 0 | 4 |
| KRT76 | NUDT7 | 0.719339 | 3 | 0 | 3 |
| KRT76 | ZNF717 | 0.716042 | 5 | 0 | 5 |
| KRT76 | MUC5AC | 0.71531 | 4 | 0 | 3 |
| KRT76 | TIAF1 | 0.715204 | 3 | 0 | 3 |
| KRT76 | BCAN | 0.710978 | 5 | 0 | 5 |
| KRT76 | NOS1 | 0.710371 | 4 | 0 | 4 |
| KRT76 | THEG | 0.709751 | 5 | 0 | 5 |
| KRT76 | GBP6 | 0.708853 | 3 | 0 | 3 |
| KRT76 | CRHR2 | 0.708457 | 5 | 0 | 5 |
| KRT76 | ARR3 | 0.706937 | 5 | 0 | 5 |
| KRT76 | DCC | 0.705331 | 4 | 0 | 4 |
| KRT76 | SLC5A4 | 0.7043 | 5 | 0 | 5 |
For details and further investigation, click here
