| Full name: F-box protein 17 | Alias Symbol: FBG4|FLJ25205|MGC9379|FLJ11798|Fbx17 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 115290 | HGNC ID: HGNC:18754 | Ensembl Gene: ENSG00000269190 | OMIM ID: 609094 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO17 | 115290 | 220233_at | 0.2389 | 0.8616 | |
| GSE20347 | FBXO17 | 115290 | 220233_at | 0.1958 | 0.2133 | |
| GSE23400 | FBXO17 | 115290 | 220233_at | -0.0298 | 0.6808 | |
| GSE26886 | FBXO17 | 115290 | 220233_at | 0.6029 | 0.0560 | |
| GSE29001 | FBXO17 | 115290 | 220233_at | 0.2545 | 0.5855 | |
| GSE38129 | FBXO17 | 115290 | 220233_at | 0.0842 | 0.7621 | |
| GSE45670 | FBXO17 | 115290 | 220233_at | -0.2474 | 0.3742 | |
| GSE53622 | FBXO17 | 115290 | 7373 | 0.3534 | 0.0015 | |
| GSE53624 | FBXO17 | 115290 | 7373 | 0.1364 | 0.3016 | |
| GSE63941 | FBXO17 | 115290 | 220233_at | -1.5625 | 0.0097 | |
| GSE77861 | FBXO17 | 115290 | 220233_at | 0.1492 | 0.3974 | |
| GSE97050 | FBXO17 | 115290 | A_23_P395911 | 0.0884 | 0.7067 | |
| SRP007169 | FBXO17 | 115290 | RNAseq | 0.8264 | 0.2741 | |
| SRP064894 | FBXO17 | 115290 | RNAseq | 0.6335 | 0.0241 | |
| SRP133303 | FBXO17 | 115290 | RNAseq | 0.3760 | 0.1410 | |
| SRP193095 | FBXO17 | 115290 | RNAseq | 0.5385 | 0.0002 | |
| SRP219564 | FBXO17 | 115290 | RNAseq | -0.0286 | 0.9596 | |
| TCGA | FBXO17 | 115290 | RNAseq | 0.1275 | 0.3982 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FBXO17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO17 | 115290 | 7 | 4 | 19 | |
| GSE20123 | FBXO17 | 115290 | 7 | 3 | 20 | |
| GSE43470 | FBXO17 | 115290 | 4 | 10 | 29 | |
| GSE46452 | FBXO17 | 115290 | 47 | 2 | 10 | |
| GSE47630 | FBXO17 | 115290 | 9 | 5 | 26 | |
| GSE54993 | FBXO17 | 115290 | 17 | 3 | 50 | |
| GSE54994 | FBXO17 | 115290 | 6 | 9 | 38 | |
| GSE60625 | FBXO17 | 115290 | 9 | 0 | 2 | |
| GSE74703 | FBXO17 | 115290 | 4 | 6 | 26 | |
| GSE74704 | FBXO17 | 115290 | 7 | 1 | 12 | |
| TCGA | FBXO17 | 115290 | 14 | 16 | 66 |
Total number of gains: 131; Total number of losses: 59; Total Number of normals: 298.
Somatic mutations of FBXO17:
Generating mutation plots.
Highly correlated genes for FBXO17:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO17 | SLC26A1 | 0.842349 | 3 | 0 | 3 |
| FBXO17 | KRTAP10-12 | 0.810559 | 3 | 0 | 3 |
| FBXO17 | OR2T27 | 0.786738 | 3 | 0 | 3 |
| FBXO17 | GYPE | 0.782679 | 4 | 0 | 4 |
| FBXO17 | TMEM229A | 0.779961 | 3 | 0 | 3 |
| FBXO17 | TCTE1 | 0.774984 | 3 | 0 | 3 |
| FBXO17 | DCDC1 | 0.774286 | 3 | 0 | 3 |
| FBXO17 | YY2 | 0.773971 | 3 | 0 | 3 |
| FBXO17 | KRTAP4-8 | 0.772635 | 3 | 0 | 3 |
| FBXO17 | PNPLA7 | 0.766681 | 4 | 0 | 4 |
| FBXO17 | STRC | 0.759535 | 3 | 0 | 3 |
| FBXO17 | DEFB108B | 0.758224 | 3 | 0 | 3 |
| FBXO17 | OR10AD1 | 0.75612 | 3 | 0 | 3 |
| FBXO17 | OR2T1 | 0.751672 | 3 | 0 | 3 |
| FBXO17 | KRTAP5-7 | 0.751126 | 3 | 0 | 3 |
| FBXO17 | CD72 | 0.747045 | 4 | 0 | 4 |
| FBXO17 | PLA2G2C | 0.74581 | 3 | 0 | 3 |
| FBXO17 | OR2A5 | 0.738721 | 3 | 0 | 3 |
| FBXO17 | C19orf44 | 0.738714 | 3 | 0 | 3 |
| FBXO17 | MUC3A | 0.734912 | 3 | 0 | 3 |
For details and further investigation, click here
