| Full name: glycerophosphodiester phosphodiesterase domain containing 5 | Alias Symbol: PP1665|GDE2 | ||
| Type: protein-coding gene | Cytoband: 11q13.4-q13.5 | ||
| Entrez ID: 81544 | HGNC ID: HGNC:28804 | Ensembl Gene: ENSG00000158555 | OMIM ID: 609632 |
| Drug and gene relationship at DGIdb | |||
Expression of GDPD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GDPD5 | 81544 | 32502_at | 0.1024 | 0.7737 | |
| GSE20347 | GDPD5 | 81544 | 32502_at | -0.0214 | 0.8301 | |
| GSE23400 | GDPD5 | 81544 | 213343_s_at | -0.1081 | 0.0369 | |
| GSE26886 | GDPD5 | 81544 | 213343_s_at | 0.4065 | 0.0042 | |
| GSE29001 | GDPD5 | 81544 | 32502_at | 0.0261 | 0.8709 | |
| GSE38129 | GDPD5 | 81544 | 32502_at | -0.2673 | 0.0494 | |
| GSE45670 | GDPD5 | 81544 | 32502_at | -0.0320 | 0.8437 | |
| GSE53622 | GDPD5 | 81544 | 29188 | 0.4311 | 0.0001 | |
| GSE53624 | GDPD5 | 81544 | 29188 | 0.6361 | 0.0000 | |
| GSE63941 | GDPD5 | 81544 | 32502_at | -0.0972 | 0.8414 | |
| GSE77861 | GDPD5 | 81544 | 32502_at | -0.0844 | 0.3719 | |
| GSE97050 | GDPD5 | 81544 | A_33_P3258330 | 0.1374 | 0.5278 | |
| SRP064894 | GDPD5 | 81544 | RNAseq | 1.2011 | 0.0009 | |
| SRP133303 | GDPD5 | 81544 | RNAseq | 0.1544 | 0.4930 | |
| SRP159526 | GDPD5 | 81544 | RNAseq | -0.0247 | 0.9323 | |
| SRP193095 | GDPD5 | 81544 | RNAseq | 1.8347 | 0.0000 | |
| SRP219564 | GDPD5 | 81544 | RNAseq | 1.0498 | 0.0191 | |
| TCGA | GDPD5 | 81544 | RNAseq | 0.1822 | 0.2217 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by GDPD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GDPD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDPD5 | 81544 | 6 | 8 | 16 | |
| GSE20123 | GDPD5 | 81544 | 6 | 7 | 17 | |
| GSE43470 | GDPD5 | 81544 | 5 | 4 | 34 | |
| GSE46452 | GDPD5 | 81544 | 7 | 22 | 30 | |
| GSE47630 | GDPD5 | 81544 | 6 | 14 | 20 | |
| GSE54993 | GDPD5 | 81544 | 8 | 2 | 60 | |
| GSE54994 | GDPD5 | 81544 | 7 | 16 | 30 | |
| GSE60625 | GDPD5 | 81544 | 4 | 3 | 4 | |
| GSE74703 | GDPD5 | 81544 | 4 | 3 | 29 | |
| GSE74704 | GDPD5 | 81544 | 4 | 3 | 13 | |
| TCGA | GDPD5 | 81544 | 21 | 32 | 43 |
Total number of gains: 78; Total number of losses: 114; Total Number of normals: 296.
Somatic mutations of GDPD5:
Generating mutation plots.
Highly correlated genes for GDPD5:
Showing top 20/325 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDPD5 | GYPE | 0.794622 | 3 | 0 | 3 |
| GDPD5 | MUC8 | 0.754243 | 3 | 0 | 3 |
| GDPD5 | RHBDD3 | 0.748957 | 3 | 0 | 3 |
| GDPD5 | HIP1R | 0.740611 | 3 | 0 | 3 |
| GDPD5 | ZAN | 0.724776 | 3 | 0 | 3 |
| GDPD5 | SYNGAP1 | 0.722041 | 3 | 0 | 3 |
| GDPD5 | MAPK15 | 0.710656 | 3 | 0 | 3 |
| GDPD5 | PHGR1 | 0.708805 | 3 | 0 | 3 |
| GDPD5 | TMUB1 | 0.705441 | 3 | 0 | 3 |
| GDPD5 | TMEM102 | 0.702658 | 3 | 0 | 3 |
| GDPD5 | C19orf81 | 0.698871 | 3 | 0 | 3 |
| GDPD5 | GPR52 | 0.698785 | 3 | 0 | 3 |
| GDPD5 | HAUS5 | 0.690465 | 4 | 0 | 4 |
| GDPD5 | ZNF221 | 0.683119 | 5 | 0 | 5 |
| GDPD5 | LINC01140 | 0.673638 | 3 | 0 | 3 |
| GDPD5 | LRTM1 | 0.671979 | 3 | 0 | 3 |
| GDPD5 | TMEM63A | 0.67101 | 3 | 0 | 3 |
| GDPD5 | SLC5A4 | 0.666511 | 4 | 0 | 3 |
| GDPD5 | LYL1 | 0.666013 | 5 | 0 | 5 |
| GDPD5 | PCSK1N | 0.665539 | 5 | 0 | 4 |
For details and further investigation, click here
