| Full name: HGF activator | Alias Symbol: HGFAP|HGFA | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 3083 | HGNC ID: HGNC:4894 | Ensembl Gene: ENSG00000109758 | OMIM ID: 604552 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HGFAC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HGFAC | 3083 | 207027_at | -0.1938 | 0.3022 | |
| GSE20347 | HGFAC | 3083 | 207027_at | -0.1141 | 0.0502 | |
| GSE23400 | HGFAC | 3083 | 207027_at | -0.1248 | 0.0004 | |
| GSE26886 | HGFAC | 3083 | 207027_at | 0.1905 | 0.1146 | |
| GSE29001 | HGFAC | 3083 | 207027_at | -0.2695 | 0.0074 | |
| GSE38129 | HGFAC | 3083 | 207027_at | -0.1240 | 0.0498 | |
| GSE45670 | HGFAC | 3083 | 207027_at | 0.0155 | 0.8970 | |
| GSE53622 | HGFAC | 3083 | 42559 | 0.4222 | 0.0000 | |
| GSE53624 | HGFAC | 3083 | 42559 | 0.3347 | 0.0008 | |
| GSE63941 | HGFAC | 3083 | 207027_at | 0.2098 | 0.1748 | |
| GSE77861 | HGFAC | 3083 | 207027_at | -0.1925 | 0.0819 | |
| GSE97050 | HGFAC | 3083 | A_33_P3267640 | -0.0818 | 0.7716 | |
| TCGA | HGFAC | 3083 | RNAseq | 1.2266 | 0.1424 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HGFAC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HGFAC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HGFAC | 3083 | 0 | 17 | 13 | |
| GSE20123 | HGFAC | 3083 | 0 | 17 | 13 | |
| GSE43470 | HGFAC | 3083 | 0 | 18 | 25 | |
| GSE46452 | HGFAC | 3083 | 1 | 36 | 22 | |
| GSE47630 | HGFAC | 3083 | 1 | 19 | 20 | |
| GSE54993 | HGFAC | 3083 | 10 | 0 | 60 | |
| GSE54994 | HGFAC | 3083 | 3 | 12 | 38 | |
| GSE60625 | HGFAC | 3083 | 0 | 0 | 11 | |
| GSE74703 | HGFAC | 3083 | 0 | 14 | 22 | |
| GSE74704 | HGFAC | 3083 | 0 | 9 | 11 | |
| TCGA | HGFAC | 3083 | 7 | 47 | 42 |
Total number of gains: 22; Total number of losses: 189; Total Number of normals: 277.
Somatic mutations of HGFAC:
Generating mutation plots.
Highly correlated genes for HGFAC:
Showing top 20/816 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HGFAC | IFNL2 | 0.757536 | 3 | 0 | 3 |
| HGFAC | LINC00523 | 0.756189 | 3 | 0 | 3 |
| HGFAC | GJD4 | 0.731829 | 5 | 0 | 5 |
| HGFAC | STARD7-AS1 | 0.729493 | 3 | 0 | 3 |
| HGFAC | BFSP2-AS1 | 0.727826 | 4 | 0 | 4 |
| HGFAC | KRT31 | 0.72358 | 3 | 0 | 3 |
| HGFAC | DEFB108B | 0.716134 | 4 | 0 | 4 |
| HGFAC | TMEM105 | 0.711931 | 4 | 0 | 4 |
| HGFAC | SYCN | 0.71014 | 3 | 0 | 3 |
| HGFAC | LINC00930 | 0.705646 | 5 | 0 | 5 |
| HGFAC | SSMEM1 | 0.703204 | 3 | 0 | 3 |
| HGFAC | NPSR1-AS1 | 0.701569 | 3 | 0 | 3 |
| HGFAC | MYO1A | 0.699159 | 4 | 0 | 4 |
| HGFAC | OR5H1 | 0.698079 | 4 | 0 | 4 |
| HGFAC | THRB | 0.697985 | 3 | 0 | 3 |
| HGFAC | LINC01281 | 0.697329 | 4 | 0 | 4 |
| HGFAC | RBAKDN | 0.695783 | 5 | 0 | 5 |
| HGFAC | DEFB128 | 0.694717 | 3 | 0 | 3 |
| HGFAC | LINC00163 | 0.694425 | 3 | 0 | 3 |
| HGFAC | LDHAL6A | 0.694101 | 3 | 0 | 3 |
For details and further investigation, click here
