| Full name: gap junction protein delta 4 | Alias Symbol: CX40.1|FLJ90023 | ||
| Type: protein-coding gene | Cytoband: 10p11.21 | ||
| Entrez ID: 219770 | HGNC ID: HGNC:23296 | Ensembl Gene: ENSG00000177291 | OMIM ID: 611922 |
| Drug and gene relationship at DGIdb | |||
Expression of GJD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GJD4 | 219770 | 234116_at | -0.0869 | 0.6858 | |
| GSE26886 | GJD4 | 219770 | 234116_at | 0.3362 | 0.0430 | |
| GSE45670 | GJD4 | 219770 | 234116_at | 0.0026 | 0.9856 | |
| GSE53622 | GJD4 | 219770 | 19696 | 0.2579 | 0.0113 | |
| GSE53624 | GJD4 | 219770 | 19696 | 0.0991 | 0.3320 | |
| GSE63941 | GJD4 | 219770 | 234116_at | 0.2153 | 0.2052 | |
| GSE77861 | GJD4 | 219770 | 234116_at | -0.2073 | 0.1359 | |
| GSE97050 | GJD4 | 219770 | A_33_P3353496 | -0.1864 | 0.3360 | |
| SRP133303 | GJD4 | 219770 | RNAseq | -0.3146 | 0.1717 | |
| TCGA | GJD4 | 219770 | RNAseq | 0.5407 | 0.5447 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GJD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GJD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GJD4 | 219770 | 3 | 7 | 20 | |
| GSE20123 | GJD4 | 219770 | 3 | 6 | 21 | |
| GSE43470 | GJD4 | 219770 | 3 | 3 | 37 | |
| GSE46452 | GJD4 | 219770 | 2 | 13 | 44 | |
| GSE47630 | GJD4 | 219770 | 7 | 10 | 23 | |
| GSE54993 | GJD4 | 219770 | 9 | 0 | 61 | |
| GSE54994 | GJD4 | 219770 | 3 | 9 | 41 | |
| GSE60625 | GJD4 | 219770 | 0 | 0 | 11 | |
| GSE74703 | GJD4 | 219770 | 2 | 1 | 33 | |
| GSE74704 | GJD4 | 219770 | 0 | 5 | 15 | |
| TCGA | GJD4 | 219770 | 17 | 24 | 55 |
Total number of gains: 49; Total number of losses: 78; Total Number of normals: 361.
Somatic mutations of GJD4:
Generating mutation plots.
Highly correlated genes for GJD4:
Showing top 20/758 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GJD4 | YY2 | 0.906339 | 3 | 0 | 3 |
| GJD4 | VHL | 0.884068 | 3 | 0 | 3 |
| GJD4 | LBX2 | 0.877065 | 3 | 0 | 3 |
| GJD4 | C9orf153 | 0.872354 | 3 | 0 | 3 |
| GJD4 | DCDC1 | 0.86841 | 3 | 0 | 3 |
| GJD4 | PRSS38 | 0.852166 | 3 | 0 | 3 |
| GJD4 | MRGPRG | 0.851071 | 3 | 0 | 3 |
| GJD4 | OR2T27 | 0.848127 | 3 | 0 | 3 |
| GJD4 | PLA2G2C | 0.846094 | 3 | 0 | 3 |
| GJD4 | STRC | 0.835273 | 3 | 0 | 3 |
| GJD4 | GRIK4 | 0.828633 | 3 | 0 | 3 |
| GJD4 | KRTAP10-12 | 0.821694 | 3 | 0 | 3 |
| GJD4 | BBC3 | 0.816346 | 3 | 0 | 3 |
| GJD4 | LRIT1 | 0.807931 | 3 | 0 | 3 |
| GJD4 | CHST10 | 0.807396 | 3 | 0 | 3 |
| GJD4 | ZNF527 | 0.805037 | 4 | 0 | 3 |
| GJD4 | C1QL2 | 0.802006 | 3 | 0 | 3 |
| GJD4 | ST8SIA1 | 0.789059 | 4 | 0 | 3 |
| GJD4 | NTNG2 | 0.781528 | 3 | 0 | 3 |
| GJD4 | OR2T1 | 0.780924 | 3 | 0 | 3 |
For details and further investigation, click here
