| Full name: defensin beta 108B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 245911 | HGNC ID: HGNC:29966 | Ensembl Gene: ENSG00000184276 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DEFB108B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DEFB108B | 245911 | 1561165_a_at | -0.1568 | 0.3497 | |
| GSE26886 | DEFB108B | 245911 | 1561165_a_at | 0.0487 | 0.5840 | |
| GSE45670 | DEFB108B | 245911 | 1561165_a_at | -0.0373 | 0.6030 | |
| GSE53622 | DEFB108B | 245911 | 79372 | 0.4374 | 0.0110 | |
| GSE53624 | DEFB108B | 245911 | 79372 | -0.0249 | 0.9008 | |
| GSE63941 | DEFB108B | 245911 | 1561165_a_at | 0.1974 | 0.1278 | |
| GSE77861 | DEFB108B | 245911 | 1561165_a_at | -0.1376 | 0.2103 | |
| GSE97050 | DEFB108B | 245911 | A_33_P3265803 | 0.0896 | 0.7533 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DEFB108B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DEFB108B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DEFB108B | 245911 | 11 | 6 | 13 | |
| GSE20123 | DEFB108B | 245911 | 11 | 6 | 13 | |
| GSE43470 | DEFB108B | 245911 | 7 | 4 | 32 | |
| GSE46452 | DEFB108B | 245911 | 13 | 16 | 30 | |
| GSE47630 | DEFB108B | 245911 | 11 | 9 | 20 | |
| GSE54993 | DEFB108B | 245911 | 7 | 4 | 59 | |
| GSE54994 | DEFB108B | 245911 | 14 | 11 | 28 | |
| GSE60625 | DEFB108B | 245911 | 0 | 7 | 4 | |
| GSE74703 | DEFB108B | 245911 | 6 | 3 | 27 | |
| GSE74704 | DEFB108B | 245911 | 7 | 4 | 9 | |
| TCGA | DEFB108B | 245911 | 38 | 19 | 39 |
Total number of gains: 125; Total number of losses: 89; Total Number of normals: 274.
Somatic mutations of DEFB108B:
Generating mutation plots.
Highly correlated genes for DEFB108B:
Showing top 20/361 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DEFB108B | KRTAP10-12 | 0.833701 | 3 | 0 | 3 |
| DEFB108B | DEFB121 | 0.814989 | 3 | 0 | 3 |
| DEFB108B | KRTAP5-7 | 0.811145 | 3 | 0 | 3 |
| DEFB108B | OR4D6 | 0.796383 | 3 | 0 | 3 |
| DEFB108B | NRSN1 | 0.790696 | 3 | 0 | 3 |
| DEFB108B | STRC | 0.784134 | 3 | 0 | 3 |
| DEFB108B | SIM1 | 0.771047 | 3 | 0 | 3 |
| DEFB108B | KDM8 | 0.761037 | 3 | 0 | 3 |
| DEFB108B | GCM2 | 0.75939 | 3 | 0 | 3 |
| DEFB108B | FBXO17 | 0.758224 | 3 | 0 | 3 |
| DEFB108B | ST8SIA3 | 0.75583 | 3 | 0 | 3 |
| DEFB108B | GPR35 | 0.754251 | 3 | 0 | 3 |
| DEFB108B | F2RL3 | 0.750737 | 4 | 0 | 4 |
| DEFB108B | SLC26A1 | 0.749132 | 4 | 0 | 4 |
| DEFB108B | GRM1 | 0.748622 | 3 | 0 | 3 |
| DEFB108B | LINC01101 | 0.740159 | 3 | 0 | 3 |
| DEFB108B | OR2C1 | 0.738639 | 4 | 0 | 4 |
| DEFB108B | SPAM1 | 0.737555 | 3 | 0 | 3 |
| DEFB108B | ANGPT4 | 0.73587 | 4 | 0 | 4 |
| DEFB108B | PLA2G2C | 0.732355 | 3 | 0 | 3 |
For details and further investigation, click here
