| Full name: myosin IA | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.3 | ||
| Entrez ID: 4640 | HGNC ID: HGNC:7595 | Ensembl Gene: ENSG00000166866 | OMIM ID: 601478 |
| Drug and gene relationship at DGIdb | |||
Expression of MYO1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYO1A | 4640 | 211916_s_at | -0.2143 | 0.4393 | |
| GSE20347 | MYO1A | 4640 | 211916_s_at | -0.1011 | 0.1895 | |
| GSE23400 | MYO1A | 4640 | 211916_s_at | -0.3595 | 0.0000 | |
| GSE26886 | MYO1A | 4640 | 211916_s_at | -0.3245 | 0.0281 | |
| GSE29001 | MYO1A | 4640 | 211916_s_at | -0.3725 | 0.0392 | |
| GSE38129 | MYO1A | 4640 | 211916_s_at | -0.1671 | 0.0848 | |
| GSE45670 | MYO1A | 4640 | 211916_s_at | 0.1430 | 0.2420 | |
| GSE53622 | MYO1A | 4640 | 66795 | 0.0124 | 0.9087 | |
| GSE53624 | MYO1A | 4640 | 66795 | -0.2149 | 0.0164 | |
| GSE63941 | MYO1A | 4640 | 211916_s_at | 0.0076 | 0.9740 | |
| GSE77861 | MYO1A | 4640 | 211916_s_at | -0.1929 | 0.0419 | |
| GSE97050 | MYO1A | 4640 | A_23_P162288 | -0.1690 | 0.4273 | |
| TCGA | MYO1A | 4640 | RNAseq | -4.4398 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MYO1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYO1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYO1A | 4640 | 7 | 1 | 22 | |
| GSE20123 | MYO1A | 4640 | 7 | 0 | 23 | |
| GSE43470 | MYO1A | 4640 | 3 | 0 | 40 | |
| GSE46452 | MYO1A | 4640 | 8 | 1 | 50 | |
| GSE47630 | MYO1A | 4640 | 10 | 2 | 28 | |
| GSE54993 | MYO1A | 4640 | 0 | 5 | 65 | |
| GSE54994 | MYO1A | 4640 | 4 | 1 | 48 | |
| GSE60625 | MYO1A | 4640 | 0 | 0 | 11 | |
| GSE74703 | MYO1A | 4640 | 3 | 0 | 33 | |
| GSE74704 | MYO1A | 4640 | 4 | 0 | 16 | |
| TCGA | MYO1A | 4640 | 14 | 10 | 72 |
Total number of gains: 60; Total number of losses: 20; Total Number of normals: 408.
Somatic mutations of MYO1A:
Generating mutation plots.
Highly correlated genes for MYO1A:
Showing top 20/1174 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYO1A | PROCA1 | 0.867581 | 3 | 0 | 3 |
| MYO1A | BEAN1 | 0.816633 | 3 | 0 | 3 |
| MYO1A | LELP1 | 0.816479 | 3 | 0 | 3 |
| MYO1A | RGL4 | 0.809823 | 3 | 0 | 3 |
| MYO1A | PTAFR | 0.774869 | 3 | 0 | 3 |
| MYO1A | EBP | 0.774857 | 3 | 0 | 3 |
| MYO1A | GPR62 | 0.771181 | 3 | 0 | 3 |
| MYO1A | MAGEA8 | 0.768062 | 3 | 0 | 3 |
| MYO1A | RETN | 0.765523 | 4 | 0 | 4 |
| MYO1A | GPR32 | 0.764756 | 3 | 0 | 3 |
| MYO1A | RAD52 | 0.755265 | 3 | 0 | 3 |
| MYO1A | KLHL10 | 0.753348 | 4 | 0 | 4 |
| MYO1A | DDC | 0.752332 | 3 | 0 | 3 |
| MYO1A | GATA2 | 0.752205 | 3 | 0 | 3 |
| MYO1A | GSTM5 | 0.745202 | 4 | 0 | 4 |
| MYO1A | TXNDC2 | 0.744539 | 3 | 0 | 3 |
| MYO1A | COX4I2 | 0.74286 | 3 | 0 | 3 |
| MYO1A | POU1F1 | 0.73675 | 3 | 0 | 3 |
| MYO1A | FAM171A2 | 0.735144 | 3 | 0 | 3 |
| MYO1A | ADIG | 0.73341 | 3 | 0 | 3 |
For details and further investigation, click here
