| Full name: iron-sulfur cluster assembly factor IBA57 | Alias Symbol: FLJ12734 | ||
| Type: protein-coding gene | Cytoband: 1q42.13 | ||
| Entrez ID: 200205 | HGNC ID: HGNC:27302 | Ensembl Gene: ENSG00000181873 | OMIM ID: 615316 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of IBA57:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IBA57 | 200205 | 1558896_at | 0.7828 | 0.4048 | |
| GSE20347 | IBA57 | 200205 | 215490_at | -0.0654 | 0.3275 | |
| GSE23400 | IBA57 | 200205 | 215490_at | -0.1465 | 0.0000 | |
| GSE26886 | IBA57 | 200205 | 236629_at | 0.0784 | 0.8180 | |
| GSE29001 | IBA57 | 200205 | 215490_at | -0.1390 | 0.2822 | |
| GSE38129 | IBA57 | 200205 | 215490_at | -0.1859 | 0.0444 | |
| GSE45670 | IBA57 | 200205 | 1558896_at | 0.1038 | 0.6359 | |
| GSE53622 | IBA57 | 200205 | 53018 | 0.0981 | 0.0342 | |
| GSE53624 | IBA57 | 200205 | 53018 | 0.1994 | 0.0059 | |
| GSE63941 | IBA57 | 200205 | 215490_at | 0.3577 | 0.0051 | |
| GSE77861 | IBA57 | 200205 | 215490_at | -0.1961 | 0.0712 | |
| GSE97050 | IBA57 | 200205 | A_33_P3215128 | -0.3543 | 0.1782 | |
| SRP007169 | IBA57 | 200205 | RNAseq | -0.0333 | 0.9383 | |
| SRP008496 | IBA57 | 200205 | RNAseq | 0.0871 | 0.8091 | |
| SRP064894 | IBA57 | 200205 | RNAseq | 0.4571 | 0.0066 | |
| SRP133303 | IBA57 | 200205 | RNAseq | -0.1903 | 0.2275 | |
| SRP159526 | IBA57 | 200205 | RNAseq | 0.2798 | 0.4137 | |
| SRP193095 | IBA57 | 200205 | RNAseq | 0.0934 | 0.2843 | |
| SRP219564 | IBA57 | 200205 | RNAseq | 0.0753 | 0.7130 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IBA57 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of IBA57:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IBA57 | 200205 | 11 | 0 | 19 | |
| GSE20123 | IBA57 | 200205 | 11 | 0 | 19 | |
| GSE43470 | IBA57 | 200205 | 7 | 1 | 35 | |
| GSE46452 | IBA57 | 200205 | 4 | 2 | 53 | |
| GSE47630 | IBA57 | 200205 | 15 | 0 | 25 | |
| GSE54993 | IBA57 | 200205 | 0 | 6 | 64 | |
| GSE54994 | IBA57 | 200205 | 17 | 0 | 36 | |
| GSE60625 | IBA57 | 200205 | 0 | 0 | 11 | |
| GSE74703 | IBA57 | 200205 | 7 | 1 | 28 | |
| GSE74704 | IBA57 | 200205 | 5 | 0 | 15 | |
| TCGA | IBA57 | 200205 | 45 | 2 | 49 |
Total number of gains: 122; Total number of losses: 12; Total Number of normals: 354.
Somatic mutations of IBA57:
Generating mutation plots.
Highly correlated genes for IBA57:
Showing top 20/449 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IBA57 | AP4S1 | 0.73282 | 6 | 0 | 6 |
| IBA57 | GDF10 | 0.710431 | 3 | 0 | 3 |
| IBA57 | KRTAP5-1 | 0.697401 | 3 | 0 | 3 |
| IBA57 | RBM38 | 0.693522 | 3 | 0 | 3 |
| IBA57 | EXOC3L4 | 0.693145 | 3 | 0 | 3 |
| IBA57 | P2RX6 | 0.689828 | 5 | 0 | 4 |
| IBA57 | POU6F1 | 0.681151 | 6 | 0 | 6 |
| IBA57 | AMELY | 0.680838 | 5 | 0 | 5 |
| IBA57 | FGF21 | 0.679648 | 5 | 0 | 4 |
| IBA57 | ZBTB37 | 0.67476 | 3 | 0 | 3 |
| IBA57 | ATF7 | 0.672414 | 5 | 0 | 4 |
| IBA57 | SLC17A4 | 0.670132 | 4 | 0 | 4 |
| IBA57 | TMPRSS15 | 0.669399 | 6 | 0 | 6 |
| IBA57 | CCDC87 | 0.667933 | 4 | 0 | 4 |
| IBA57 | SERINC2 | 0.666108 | 4 | 0 | 4 |
| IBA57 | IFNA10 | 0.665656 | 5 | 0 | 5 |
| IBA57 | KIAA1614 | 0.665523 | 6 | 0 | 5 |
| IBA57 | DNAAF1 | 0.664043 | 5 | 0 | 5 |
| IBA57 | C16orf90 | 0.663517 | 3 | 0 | 3 |
| IBA57 | IGH | 0.663017 | 5 | 0 | 5 |
For details and further investigation, click here
