IFNA10

 

Full name: interferon alpha 10 Alias Symbol: IFN-alphaC
Type: protein-coding gene Cytoband: 9p21.3
Entrez ID: 3446 HGNC ID: HGNC:5418 Ensembl Gene: ENSG00000186803 OMIM ID: 147577
Drug and gene relationship at DGIdb

 

IFNA10 involved pathways:

KEGG pathway Description View
hsa04151PI3K-Akt signaling pathway
hsa04620Toll-like receptor signaling pathway
hsa04630Jak-STAT signaling pathway
hsa04650Natural killer cell mediated cytotoxicity
hsa05152Tuberculosis
hsa05160Hepatitis C
hsa05161Hepatitis B
hsa05162Measles

 

Expression of IFNA10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IFNA10 3446 208261_x_at -0.1644 0.4989
GSE20347 IFNA10 3446 208261_x_at 0.0404 0.6678
GSE23400 IFNA10 3446 208261_x_at -0.1258 0.0009
GSE26886 IFNA10 3446 208261_x_at -0.2406 0.0049
GSE29001 IFNA10 3446 208261_x_at -0.2716 0.0676
GSE38129 IFNA10 3446 208261_x_at -0.0820 0.2903
GSE45670 IFNA10 3446 208261_x_at -0.0575 0.4327
GSE53622 IFNA10 3446 16092 -0.1805 0.0639
GSE53624 IFNA10 3446 16092 0.1068 0.2661
GSE63941 IFNA10 3446 208261_x_at 0.0034 0.9815
GSE77861 IFNA10 3446 208261_x_at -0.1802 0.0248

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by IFNA10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of IFNA10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IFNA10 3446 2 17 11
GSE20123 IFNA10 3446 2 17 11
GSE43470 IFNA10 3446 4 13 26
GSE46452 IFNA10 3446 2 23 34
GSE47630 IFNA10 3446 3 27 10
GSE54993 IFNA10 3446 7 2 61
GSE54994 IFNA10 3446 8 16 29
GSE60625 IFNA10 3446 3 0 8
GSE74703 IFNA10 3446 4 10 22
GSE74704 IFNA10 3446 0 13 7
TCGA IFNA10 3446 11 53 32

Total number of gains: 46; Total number of losses: 191; Total Number of normals: 251.  

 

Somatic mutations of IFNA10:

 

Generating mutation plots.

 

Highly correlated genes for IFNA10:

 

Showing top 20/1154 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IFNA10CHGA0.763702303
IFNA10FBP20.756543404
IFNA10NKX6-10.741444303
IFNA10CIITA0.735164505
IFNA10HSPB60.733465303
IFNA10LUZP40.729685505
IFNA10GPA330.725702404
IFNA10KRT840.720868303
IFNA10CAMK2B0.71469505
IFNA10HRG0.71468404
IFNA10RBP40.713762303
IFNA10CACNB10.71079505
IFNA10C8A0.708259505
IFNA10GALR30.707704403
IFNA10CACNG10.707506404
IFNA10NCR20.707445505
IFNA10DAB10.704454505
IFNA10DUOX10.704342303
IFNA10PYHIN10.703837505
IFNA10CDKL50.703339403

For details and further investigation, click here