| Full name: activating transcription factor 7 | Alias Symbol: ATFA | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 11016 | HGNC ID: HGNC:792 | Ensembl Gene: ENSG00000170653 | OMIM ID: 606371 |
| Drug and gene relationship at DGIdb | |||
Expression of ATF7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATF7 | 11016 | 228829_at | -0.5732 | 0.1437 | |
| GSE20347 | ATF7 | 11016 | 206684_s_at | 0.0488 | 0.5557 | |
| GSE23400 | ATF7 | 11016 | 206684_s_at | -0.0169 | 0.5906 | |
| GSE26886 | ATF7 | 11016 | 228829_at | 0.1088 | 0.5768 | |
| GSE29001 | ATF7 | 11016 | 206684_s_at | -0.1496 | 0.3341 | |
| GSE38129 | ATF7 | 11016 | 206684_s_at | -0.1020 | 0.2968 | |
| GSE45670 | ATF7 | 11016 | 228829_at | -0.5497 | 0.0012 | |
| GSE53622 | ATF7 | 11016 | 79608 | -0.0854 | 0.2148 | |
| GSE53624 | ATF7 | 11016 | 79608 | -0.0678 | 0.2603 | |
| GSE63941 | ATF7 | 11016 | 228829_at | -0.0226 | 0.9745 | |
| GSE77861 | ATF7 | 11016 | 244587_at | -0.1280 | 0.4794 | |
| GSE97050 | ATF7 | 11016 | A_23_P361495 | -0.5172 | 0.1726 | |
| SRP007169 | ATF7 | 11016 | RNAseq | -1.0498 | 0.0015 | |
| SRP008496 | ATF7 | 11016 | RNAseq | -0.7381 | 0.0036 | |
| SRP064894 | ATF7 | 11016 | RNAseq | -0.6185 | 0.0001 | |
| SRP133303 | ATF7 | 11016 | RNAseq | -0.2011 | 0.0324 | |
| SRP159526 | ATF7 | 11016 | RNAseq | -0.3763 | 0.0427 | |
| SRP193095 | ATF7 | 11016 | RNAseq | -0.3974 | 0.0002 | |
| SRP219564 | ATF7 | 11016 | RNAseq | -0.6263 | 0.0444 | |
| TCGA | ATF7 | 11016 | RNAseq | -0.0763 | 0.0781 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATF7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATF7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATF7 | 11016 | 7 | 1 | 22 | |
| GSE20123 | ATF7 | 11016 | 7 | 1 | 22 | |
| GSE43470 | ATF7 | 11016 | 3 | 0 | 40 | |
| GSE46452 | ATF7 | 11016 | 7 | 1 | 51 | |
| GSE47630 | ATF7 | 11016 | 10 | 2 | 28 | |
| GSE54993 | ATF7 | 11016 | 0 | 5 | 65 | |
| GSE54994 | ATF7 | 11016 | 4 | 1 | 48 | |
| GSE60625 | ATF7 | 11016 | 0 | 0 | 11 | |
| GSE74703 | ATF7 | 11016 | 3 | 0 | 33 | |
| GSE74704 | ATF7 | 11016 | 5 | 1 | 14 | |
| TCGA | ATF7 | 11016 | 15 | 11 | 70 |
Total number of gains: 61; Total number of losses: 23; Total Number of normals: 404.
Somatic mutations of ATF7:
Generating mutation plots.
Highly correlated genes for ATF7:
Showing top 20/732 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATF7 | MPP7 | 0.814723 | 3 | 0 | 3 |
| ATF7 | ALG12 | 0.781976 | 3 | 0 | 3 |
| ATF7 | SPAG16 | 0.772229 | 3 | 0 | 3 |
| ATF7 | ACADSB | 0.771203 | 3 | 0 | 3 |
| ATF7 | SLTM | 0.770381 | 3 | 0 | 3 |
| ATF7 | MSRA | 0.76735 | 4 | 0 | 4 |
| ATF7 | HIPK3 | 0.767308 | 3 | 0 | 3 |
| ATF7 | SMAP1 | 0.766815 | 3 | 0 | 3 |
| ATF7 | CUL3 | 0.76422 | 3 | 0 | 3 |
| ATF7 | CRYBB2 | 0.764199 | 3 | 0 | 3 |
| ATF7 | EFR3B | 0.76412 | 4 | 0 | 4 |
| ATF7 | CPEB4 | 0.762051 | 3 | 0 | 3 |
| ATF7 | BEX4 | 0.758555 | 3 | 0 | 3 |
| ATF7 | CDH6 | 0.75692 | 3 | 0 | 3 |
| ATF7 | CHMP2B | 0.756548 | 3 | 0 | 3 |
| ATF7 | MID2 | 0.755601 | 3 | 0 | 3 |
| ATF7 | RNF207 | 0.751344 | 3 | 0 | 3 |
| ATF7 | RAB11A | 0.748383 | 3 | 0 | 3 |
| ATF7 | KAT2B | 0.748111 | 3 | 0 | 3 |
| ATF7 | PDHB | 0.746399 | 4 | 0 | 3 |
For details and further investigation, click here
