| Full name: potassium channel tetramerization domain containing 6 | Alias Symbol: MGC27385|KCASH3 | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 200845 | HGNC ID: HGNC:22235 | Ensembl Gene: ENSG00000168301 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KCTD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCTD6 | 200845 | 238077_at | -1.1344 | 0.0086 | |
| GSE26886 | KCTD6 | 200845 | 238077_at | -1.3976 | 0.0000 | |
| GSE45670 | KCTD6 | 200845 | 238077_at | -0.9945 | 0.0001 | |
| GSE53622 | KCTD6 | 200845 | 92504 | -1.3590 | 0.0000 | |
| GSE53624 | KCTD6 | 200845 | 92504 | -1.3119 | 0.0000 | |
| GSE63941 | KCTD6 | 200845 | 238077_at | -1.1859 | 0.0431 | |
| GSE77861 | KCTD6 | 200845 | 238077_at | -1.0999 | 0.0083 | |
| GSE97050 | KCTD6 | 200845 | A_23_P385246 | -0.3005 | 0.1907 | |
| SRP007169 | KCTD6 | 200845 | RNAseq | -1.8687 | 0.0004 | |
| SRP008496 | KCTD6 | 200845 | RNAseq | -1.8114 | 0.0000 | |
| SRP064894 | KCTD6 | 200845 | RNAseq | -1.0447 | 0.0000 | |
| SRP133303 | KCTD6 | 200845 | RNAseq | -1.1363 | 0.0000 | |
| SRP159526 | KCTD6 | 200845 | RNAseq | -1.3516 | 0.0000 | |
| SRP193095 | KCTD6 | 200845 | RNAseq | -1.1195 | 0.0000 | |
| SRP219564 | KCTD6 | 200845 | RNAseq | -1.1470 | 0.0007 | |
| TCGA | KCTD6 | 200845 | RNAseq | -0.3694 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by KCTD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCTD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCTD6 | 200845 | 0 | 17 | 13 | |
| GSE20123 | KCTD6 | 200845 | 0 | 18 | 12 | |
| GSE43470 | KCTD6 | 200845 | 0 | 17 | 26 | |
| GSE46452 | KCTD6 | 200845 | 2 | 17 | 40 | |
| GSE47630 | KCTD6 | 200845 | 1 | 24 | 15 | |
| GSE54993 | KCTD6 | 200845 | 6 | 2 | 62 | |
| GSE54994 | KCTD6 | 200845 | 0 | 32 | 21 | |
| GSE60625 | KCTD6 | 200845 | 5 | 0 | 6 | |
| GSE74703 | KCTD6 | 200845 | 0 | 14 | 22 | |
| GSE74704 | KCTD6 | 200845 | 0 | 11 | 9 | |
| TCGA | KCTD6 | 200845 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of KCTD6:
Generating mutation plots.
Highly correlated genes for KCTD6:
Showing top 20/1669 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCTD6 | GOLGA4 | 0.810241 | 5 | 0 | 5 |
| KCTD6 | LRRFIP2 | 0.810197 | 7 | 0 | 7 |
| KCTD6 | RAB5A | 0.804147 | 7 | 0 | 7 |
| KCTD6 | ZNF662 | 0.799923 | 7 | 0 | 7 |
| KCTD6 | SMDT1 | 0.795133 | 3 | 0 | 3 |
| KCTD6 | DOCK9 | 0.793418 | 7 | 0 | 7 |
| KCTD6 | FBXO3 | 0.788613 | 6 | 0 | 6 |
| KCTD6 | TBC1D22B | 0.78802 | 4 | 0 | 4 |
| KCTD6 | SAMD3 | 0.784773 | 3 | 0 | 3 |
| KCTD6 | XPC | 0.784382 | 3 | 0 | 3 |
| KCTD6 | UBL3 | 0.78123 | 6 | 0 | 6 |
| KCTD6 | SLC25A46 | 0.780741 | 3 | 0 | 3 |
| KCTD6 | KAT2B | 0.775786 | 7 | 0 | 7 |
| KCTD6 | MKRN2 | 0.775424 | 5 | 0 | 5 |
| KCTD6 | SLC46A2 | 0.775225 | 7 | 0 | 7 |
| KCTD6 | CAB39L | 0.77174 | 8 | 0 | 8 |
| KCTD6 | CHMP2B | 0.769135 | 7 | 0 | 7 |
| KCTD6 | GDPD3 | 0.767054 | 6 | 0 | 6 |
| KCTD6 | FCHO2 | 0.765169 | 7 | 0 | 7 |
| KCTD6 | CPPED1 | 0.764786 | 7 | 0 | 7 |
For details and further investigation, click here
