| Full name: makorin ring finger protein 2 | Alias Symbol: RNF62|HSPC070 | ||
| Type: protein-coding gene | Cytoband: 3p25.2 | ||
| Entrez ID: 23609 | HGNC ID: HGNC:7113 | Ensembl Gene: ENSG00000075975 | OMIM ID: 608426 |
| Drug and gene relationship at DGIdb | |||
Expression of MKRN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MKRN2 | 23609 | 218071_s_at | -0.3397 | 0.0939 | |
| GSE20347 | MKRN2 | 23609 | 218071_s_at | -0.6534 | 0.0001 | |
| GSE23400 | MKRN2 | 23609 | 218071_s_at | -0.3149 | 0.0000 | |
| GSE26886 | MKRN2 | 23609 | 218071_s_at | -0.7890 | 0.0003 | |
| GSE29001 | MKRN2 | 23609 | 218071_s_at | -0.6144 | 0.0009 | |
| GSE38129 | MKRN2 | 23609 | 218071_s_at | -0.6711 | 0.0000 | |
| GSE45670 | MKRN2 | 23609 | 218071_s_at | -0.4040 | 0.0031 | |
| GSE63941 | MKRN2 | 23609 | 218071_s_at | -1.0228 | 0.0311 | |
| GSE77861 | MKRN2 | 23609 | 218071_s_at | -0.7539 | 0.0003 | |
| GSE97050 | MKRN2 | 23609 | A_23_P57807 | -0.4446 | 0.1403 | |
| SRP007169 | MKRN2 | 23609 | RNAseq | -1.6978 | 0.0000 | |
| SRP008496 | MKRN2 | 23609 | RNAseq | -1.3549 | 0.0000 | |
| SRP064894 | MKRN2 | 23609 | RNAseq | -0.6861 | 0.0000 | |
| SRP133303 | MKRN2 | 23609 | RNAseq | -0.4797 | 0.0014 | |
| SRP159526 | MKRN2 | 23609 | RNAseq | -0.7950 | 0.0003 | |
| SRP193095 | MKRN2 | 23609 | RNAseq | -0.8002 | 0.0000 | |
| SRP219564 | MKRN2 | 23609 | RNAseq | -0.8552 | 0.0047 | |
| TCGA | MKRN2 | 23609 | RNAseq | -0.1323 | 0.0112 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by MKRN2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MKRN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MKRN2 | 23609 | 1 | 17 | 12 | |
| GSE20123 | MKRN2 | 23609 | 1 | 18 | 11 | |
| GSE43470 | MKRN2 | 23609 | 0 | 21 | 22 | |
| GSE46452 | MKRN2 | 23609 | 2 | 17 | 40 | |
| GSE47630 | MKRN2 | 23609 | 2 | 23 | 15 | |
| GSE54993 | MKRN2 | 23609 | 6 | 1 | 63 | |
| GSE54994 | MKRN2 | 23609 | 1 | 33 | 19 | |
| GSE60625 | MKRN2 | 23609 | 5 | 0 | 6 | |
| GSE74703 | MKRN2 | 23609 | 0 | 17 | 19 | |
| GSE74704 | MKRN2 | 23609 | 1 | 10 | 9 | |
| TCGA | MKRN2 | 23609 | 1 | 68 | 27 |
Total number of gains: 20; Total number of losses: 225; Total Number of normals: 243.
Somatic mutations of MKRN2:
Generating mutation plots.
Highly correlated genes for MKRN2:
Showing top 20/1406 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MKRN2 | TIFA | 0.819676 | 4 | 0 | 4 |
| MKRN2 | SLTM | 0.798141 | 4 | 0 | 4 |
| MKRN2 | GPBP1 | 0.785757 | 3 | 0 | 3 |
| MKRN2 | YPEL3 | 0.785553 | 4 | 0 | 4 |
| MKRN2 | NAA35 | 0.784042 | 3 | 0 | 3 |
| MKRN2 | COMMD1 | 0.783958 | 4 | 0 | 4 |
| MKRN2 | MAGI3 | 0.781636 | 4 | 0 | 4 |
| MKRN2 | KCTD6 | 0.775424 | 5 | 0 | 5 |
| MKRN2 | RAF1 | 0.775316 | 11 | 0 | 11 |
| MKRN2 | BRK1 | 0.769962 | 6 | 0 | 6 |
| MKRN2 | FAM214A | 0.768511 | 4 | 0 | 4 |
| MKRN2 | FAM122A | 0.768215 | 3 | 0 | 3 |
| MKRN2 | MRPS36 | 0.767124 | 5 | 0 | 5 |
| MKRN2 | CGNL1 | 0.764538 | 5 | 0 | 5 |
| MKRN2 | AKAP7 | 0.764079 | 3 | 0 | 3 |
| MKRN2 | PHYHD1 | 0.761878 | 4 | 0 | 4 |
| MKRN2 | KLB | 0.760951 | 4 | 0 | 4 |
| MKRN2 | NAA20 | 0.758981 | 3 | 0 | 3 |
| MKRN2 | HDHD2 | 0.75759 | 5 | 0 | 5 |
| MKRN2 | SH3BGRL2 | 0.756613 | 5 | 0 | 5 |
For details and further investigation, click here
