BRINP1

 

Full name: BMP/retinoic acid inducible neural specific 1 Alias Symbol: FAM5A
Type: protein-coding gene Cytoband: 9q33.1
Entrez ID: 1620 HGNC ID: HGNC:2687 Ensembl Gene: ENSG00000078725 OMIM ID: 602865
Drug and gene relationship at DGIdb

 

Expression of BRINP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BRINP1 1620 205818_at -0.4857 0.3313
GSE20347 BRINP1 1620 205818_at -0.0288 0.7780
GSE23400 BRINP1 1620 205818_at -0.0116 0.7434
GSE26886 BRINP1 1620 205818_at 0.0672 0.7814
GSE29001 BRINP1 1620 205818_at -0.4153 0.0469
GSE38129 BRINP1 1620 205818_at -0.0881 0.3344
GSE45670 BRINP1 1620 205818_at 0.2273 0.5185
GSE53622 BRINP1 1620 89841 -0.4415 0.0815
GSE53624 BRINP1 1620 89841 -1.8053 0.0000
GSE63941 BRINP1 1620 205818_at -3.1092 0.0000
GSE77861 BRINP1 1620 205818_at -0.1676 0.0553
SRP159526 BRINP1 1620 RNAseq -0.4860 0.5951

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by BRINP1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of BRINP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BRINP1 1620 4 10 16
GSE20123 BRINP1 1620 4 10 16
GSE43470 BRINP1 1620 4 5 34
GSE46452 BRINP1 1620 6 13 40
GSE47630 BRINP1 1620 3 16 21
GSE54993 BRINP1 1620 3 3 64
GSE54994 BRINP1 1620 9 10 34
GSE60625 BRINP1 1620 0 0 11
GSE74703 BRINP1 1620 4 4 28
GSE74704 BRINP1 1620 2 6 12

Total number of gains: 39; Total number of losses: 77; Total Number of normals: 276.  


 

Somatic mutations of BRINP1:

 

Generating mutation plots.

 

Highly correlated genes for BRINP1:

 

Showing top 20/375 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BRINP1SLC27A60.727694303
BRINP1PDZRN30.715077303
BRINP1PEG30.704466303
BRINP1CRHR20.693574404
BRINP1PROP10.682584303
BRINP1IL12A-AS10.673943303
BRINP1PTN0.673316303
BRINP1EPHA50.666522303
BRINP1TMEM1000.665185303
BRINP1LRRK20.664006303
BRINP1CCDC1700.654833403
BRINP1BOC0.650431303
BRINP1SH3D190.649548303
BRINP1G6PC0.646061403
BRINP1CNTN40.643415303
BRINP1PDLIM20.637548404
BRINP1COL14A10.633737404
BRINP1GNA140.632157504
BRINP1OR7C20.6306403
BRINP1MCEE0.6304303

For details and further investigation, click here