| Full name: kelch like family member 14 | Alias Symbol: KIAA1384 | ||
| Type: protein-coding gene | Cytoband: 18q12.1 | ||
| Entrez ID: 57565 | HGNC ID: HGNC:29266 | Ensembl Gene: ENSG00000197705 | OMIM ID: 613772 |
| Drug and gene relationship at DGIdb | |||
Expression of KLHL14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL14 | 57565 | 1554942_a_at | 0.2414 | 0.3408 | |
| GSE26886 | KLHL14 | 57565 | 1554942_a_at | 0.1429 | 0.2483 | |
| GSE45670 | KLHL14 | 57565 | 1554942_a_at | -0.0324 | 0.7266 | |
| GSE53622 | KLHL14 | 57565 | 10988 | 0.0326 | 0.7173 | |
| GSE53624 | KLHL14 | 57565 | 10988 | 0.1418 | 0.0937 | |
| GSE63941 | KLHL14 | 57565 | 1554942_a_at | 0.2014 | 0.1513 | |
| GSE77861 | KLHL14 | 57565 | 1554942_a_at | -0.1183 | 0.4602 | |
| GSE97050 | KLHL14 | 57565 | A_32_P75357 | 0.0942 | 0.6268 | |
| SRP133303 | KLHL14 | 57565 | RNAseq | -1.7876 | 0.0000 | |
| SRP159526 | KLHL14 | 57565 | RNAseq | -2.0367 | 0.0062 | |
| TCGA | KLHL14 | 57565 | RNAseq | -0.4981 | 0.4571 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by KLHL14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHL14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL14 | 57565 | 1 | 6 | 23 | |
| GSE20123 | KLHL14 | 57565 | 1 | 6 | 23 | |
| GSE43470 | KLHL14 | 57565 | 0 | 3 | 40 | |
| GSE46452 | KLHL14 | 57565 | 1 | 25 | 33 | |
| GSE47630 | KLHL14 | 57565 | 5 | 20 | 15 | |
| GSE54993 | KLHL14 | 57565 | 8 | 1 | 61 | |
| GSE54994 | KLHL14 | 57565 | 1 | 16 | 36 | |
| GSE60625 | KLHL14 | 57565 | 0 | 4 | 7 | |
| GSE74703 | KLHL14 | 57565 | 0 | 3 | 33 | |
| GSE74704 | KLHL14 | 57565 | 0 | 5 | 15 | |
| TCGA | KLHL14 | 57565 | 14 | 34 | 48 |
Total number of gains: 31; Total number of losses: 123; Total Number of normals: 334.
Somatic mutations of KLHL14:
Generating mutation plots.
Highly correlated genes for KLHL14:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL14 | PABPN1L | 0.833798 | 3 | 0 | 3 |
| KLHL14 | LYZL2 | 0.787579 | 3 | 0 | 3 |
| KLHL14 | C1QL2 | 0.775535 | 3 | 0 | 3 |
| KLHL14 | YY2 | 0.773732 | 3 | 0 | 3 |
| KLHL14 | BSX | 0.773373 | 3 | 0 | 3 |
| KLHL14 | ZDHHC8 | 0.764737 | 3 | 0 | 3 |
| KLHL14 | PRSS38 | 0.763509 | 3 | 0 | 3 |
| KLHL14 | BBC3 | 0.763328 | 3 | 0 | 3 |
| KLHL14 | FOXA3 | 0.761418 | 3 | 0 | 3 |
| KLHL14 | OR2T27 | 0.754108 | 3 | 0 | 3 |
| KLHL14 | SLC19A3 | 0.754066 | 3 | 0 | 3 |
| KLHL14 | DCDC1 | 0.751597 | 3 | 0 | 3 |
| KLHL14 | MUC3A | 0.749956 | 3 | 0 | 3 |
| KLHL14 | C3orf36 | 0.749308 | 3 | 0 | 3 |
| KLHL14 | PNMA3 | 0.747156 | 3 | 0 | 3 |
| KLHL14 | PDE6C | 0.747089 | 3 | 0 | 3 |
| KLHL14 | C9orf153 | 0.733053 | 3 | 0 | 3 |
| KLHL14 | AANAT | 0.726179 | 3 | 0 | 3 |
| KLHL14 | MRGPRG | 0.723827 | 3 | 0 | 3 |
| KLHL14 | BMP8B | 0.721971 | 4 | 0 | 4 |
For details and further investigation, click here
