| Full name: zinc finger DHHC-type containing 8 | Alias Symbol: ZNF378|KIAA1292 | ||
| Type: protein-coding gene | Cytoband: 22q11.21 | ||
| Entrez ID: 29801 | HGNC ID: HGNC:18474 | Ensembl Gene: ENSG00000099904 | OMIM ID: 608784 |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC8 | 29801 | 225744_at | 0.9134 | 0.0147 | |
| GSE26886 | ZDHHC8 | 29801 | 230731_x_at | 0.1548 | 0.1805 | |
| GSE45670 | ZDHHC8 | 29801 | 230731_x_at | 0.1068 | 0.1340 | |
| GSE53622 | ZDHHC8 | 29801 | 6275 | 0.5626 | 0.0000 | |
| GSE53624 | ZDHHC8 | 29801 | 6275 | 0.6388 | 0.0000 | |
| GSE63941 | ZDHHC8 | 29801 | 225744_at | -0.5106 | 0.2502 | |
| GSE77861 | ZDHHC8 | 29801 | 230731_x_at | 0.2195 | 0.0385 | |
| GSE97050 | ZDHHC8 | 29801 | A_33_P3313846 | -0.1555 | 0.4983 | |
| SRP007169 | ZDHHC8 | 29801 | RNAseq | 1.5168 | 0.0027 | |
| SRP008496 | ZDHHC8 | 29801 | RNAseq | 0.9728 | 0.0058 | |
| SRP064894 | ZDHHC8 | 29801 | RNAseq | 1.1142 | 0.0000 | |
| SRP133303 | ZDHHC8 | 29801 | RNAseq | 0.0661 | 0.7773 | |
| SRP159526 | ZDHHC8 | 29801 | RNAseq | 0.6202 | 0.0794 | |
| SRP193095 | ZDHHC8 | 29801 | RNAseq | 0.7189 | 0.0000 | |
| SRP219564 | ZDHHC8 | 29801 | RNAseq | 0.5478 | 0.0165 | |
| TCGA | ZDHHC8 | 29801 | RNAseq | 0.1506 | 0.0063 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZDHHC8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC8 | 29801 | 5 | 7 | 18 | |
| GSE20123 | ZDHHC8 | 29801 | 5 | 7 | 18 | |
| GSE43470 | ZDHHC8 | 29801 | 4 | 7 | 32 | |
| GSE46452 | ZDHHC8 | 29801 | 33 | 1 | 25 | |
| GSE47630 | ZDHHC8 | 29801 | 8 | 5 | 27 | |
| GSE54993 | ZDHHC8 | 29801 | 3 | 6 | 61 | |
| GSE54994 | ZDHHC8 | 29801 | 12 | 7 | 34 | |
| GSE60625 | ZDHHC8 | 29801 | 5 | 0 | 6 | |
| GSE74703 | ZDHHC8 | 29801 | 4 | 5 | 27 | |
| GSE74704 | ZDHHC8 | 29801 | 3 | 4 | 13 | |
| TCGA | ZDHHC8 | 29801 | 27 | 17 | 52 |
Total number of gains: 109; Total number of losses: 66; Total Number of normals: 313.
Somatic mutations of ZDHHC8:
Generating mutation plots.
Highly correlated genes for ZDHHC8:
Showing top 20/294 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC8 | TAF5L | 0.819421 | 3 | 0 | 3 |
| ZDHHC8 | KLHL14 | 0.764737 | 3 | 0 | 3 |
| ZDHHC8 | CFC1 | 0.758 | 3 | 0 | 3 |
| ZDHHC8 | RBM28 | 0.753618 | 3 | 0 | 3 |
| ZDHHC8 | CCDC142 | 0.747196 | 3 | 0 | 3 |
| ZDHHC8 | SLC52A2 | 0.746383 | 3 | 0 | 3 |
| ZDHHC8 | TIGD5 | 0.74417 | 4 | 0 | 4 |
| ZDHHC8 | C19orf53 | 0.740698 | 3 | 0 | 3 |
| ZDHHC8 | STX1A | 0.738234 | 3 | 0 | 3 |
| ZDHHC8 | AIRE | 0.725238 | 3 | 0 | 3 |
| ZDHHC8 | PSTPIP1 | 0.722037 | 3 | 0 | 3 |
| ZDHHC8 | HOXC9 | 0.716535 | 4 | 0 | 3 |
| ZDHHC8 | HOXA11 | 0.710961 | 3 | 0 | 3 |
| ZDHHC8 | RHBDD3 | 0.705896 | 4 | 0 | 4 |
| ZDHHC8 | HIVEP2 | 0.703084 | 3 | 0 | 3 |
| ZDHHC8 | PRR7 | 0.701342 | 4 | 0 | 3 |
| ZDHHC8 | TP53BP1 | 0.69964 | 4 | 0 | 3 |
| ZDHHC8 | SMG5 | 0.695414 | 5 | 0 | 3 |
| ZDHHC8 | TNFAIP8L1 | 0.694665 | 4 | 0 | 3 |
| ZDHHC8 | RHBDL1 | 0.694192 | 5 | 0 | 4 |
For details and further investigation, click here
