| Full name: aralkylamine N-acetyltransferase | Alias Symbol: SNAT | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 15 | HGNC ID: HGNC:19 | Ensembl Gene: ENSG00000129673 | OMIM ID: 600950 |
| Drug and gene relationship at DGIdb | |||
Expression of AANAT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AANAT | 15 | 207225_at | 0.0538 | 0.8466 | |
| GSE20347 | AANAT | 15 | 207225_at | -0.1784 | 0.0061 | |
| GSE23400 | AANAT | 15 | 207225_at | -0.1134 | 0.0000 | |
| GSE26886 | AANAT | 15 | 207225_at | 0.0794 | 0.5327 | |
| GSE29001 | AANAT | 15 | 207225_at | -0.0438 | 0.7024 | |
| GSE38129 | AANAT | 15 | 207225_at | -0.1619 | 0.0018 | |
| GSE45670 | AANAT | 15 | 207225_at | 0.1049 | 0.2196 | |
| GSE53622 | AANAT | 15 | 81372 | 0.1356 | 0.0374 | |
| GSE53624 | AANAT | 15 | 95637 | 0.0571 | 0.5239 | |
| GSE63941 | AANAT | 15 | 207225_at | 0.1784 | 0.1504 | |
| GSE77861 | AANAT | 15 | 207225_at | -0.0363 | 0.7777 | |
| GSE97050 | AANAT | 15 | A_33_P3246763 | 0.0112 | 0.9698 | |
| SRP133303 | AANAT | 15 | RNAseq | -0.0230 | 0.9418 | |
| TCGA | AANAT | 15 | RNAseq | 1.5324 | 0.0031 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by AANAT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AANAT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AANAT | 15 | 7 | 2 | 21 | |
| GSE20123 | AANAT | 15 | 7 | 2 | 21 | |
| GSE43470 | AANAT | 15 | 5 | 3 | 35 | |
| GSE46452 | AANAT | 15 | 33 | 1 | 25 | |
| GSE47630 | AANAT | 15 | 8 | 1 | 31 | |
| GSE54993 | AANAT | 15 | 2 | 5 | 63 | |
| GSE54994 | AANAT | 15 | 10 | 4 | 39 | |
| GSE60625 | AANAT | 15 | 6 | 0 | 5 | |
| GSE74703 | AANAT | 15 | 5 | 1 | 30 | |
| GSE74704 | AANAT | 15 | 5 | 1 | 14 | |
| TCGA | AANAT | 15 | 31 | 10 | 55 |
Total number of gains: 119; Total number of losses: 30; Total Number of normals: 339.
Somatic mutations of AANAT:
Generating mutation plots.
Highly correlated genes for AANAT:
Showing top 20/640 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AANAT | INSC | 0.825455 | 3 | 0 | 3 |
| AANAT | OR2B11 | 0.825091 | 3 | 0 | 3 |
| AANAT | OR2T1 | 0.820547 | 3 | 0 | 3 |
| AANAT | PRSS38 | 0.819196 | 3 | 0 | 3 |
| AANAT | OTOG | 0.808817 | 3 | 0 | 3 |
| AANAT | LYZL2 | 0.803001 | 3 | 0 | 3 |
| AANAT | SLC22A12 | 0.794144 | 3 | 0 | 3 |
| AANAT | OR7G2 | 0.784562 | 3 | 0 | 3 |
| AANAT | BSX | 0.781337 | 3 | 0 | 3 |
| AANAT | LRRC45 | 0.777909 | 3 | 0 | 3 |
| AANAT | OR4C6 | 0.776101 | 3 | 0 | 3 |
| AANAT | OR2D2 | 0.772702 | 3 | 0 | 3 |
| AANAT | SPACA5 | 0.771998 | 3 | 0 | 3 |
| AANAT | YY2 | 0.771007 | 3 | 0 | 3 |
| AANAT | OR2A5 | 0.76789 | 3 | 0 | 3 |
| AANAT | OR4A15 | 0.767811 | 3 | 0 | 3 |
| AANAT | DCDC1 | 0.765441 | 3 | 0 | 3 |
| AANAT | SYT3 | 0.762768 | 3 | 0 | 3 |
| AANAT | C1QL2 | 0.75426 | 3 | 0 | 3 |
| AANAT | SLC5A11 | 0.751755 | 3 | 0 | 3 |
For details and further investigation, click here
