| Full name: late cornified envelope 3C | Alias Symbol: LEP15 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 353144 | HGNC ID: HGNC:16612 | Ensembl Gene: ENSG00000244057 | OMIM ID: 612615 |
| Drug and gene relationship at DGIdb | |||
Expression of LCE3C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | LCE3C | 353144 | 13749 | -0.0666 | 0.8534 | |
| GSE53624 | LCE3C | 353144 | 13749 | -0.7730 | 0.0011 | |
| GSE97050 | LCE3C | 353144 | A_23_P405295 | 0.1670 | 0.7330 | |
| TCGA | LCE3C | 353144 | RNAseq | 2.2815 | 0.1910 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LCE3C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LCE3C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCE3C | 353144 | 14 | 0 | 16 | |
| GSE20123 | LCE3C | 353144 | 14 | 0 | 16 | |
| GSE43470 | LCE3C | 353144 | 6 | 2 | 35 | |
| GSE46452 | LCE3C | 353144 | 2 | 1 | 56 | |
| GSE47630 | LCE3C | 353144 | 15 | 0 | 25 | |
| GSE54993 | LCE3C | 353144 | 0 | 4 | 66 | |
| GSE54994 | LCE3C | 353144 | 15 | 0 | 38 | |
| GSE60625 | LCE3C | 353144 | 0 | 0 | 11 | |
| GSE74703 | LCE3C | 353144 | 6 | 1 | 29 | |
| GSE74704 | LCE3C | 353144 | 7 | 0 | 13 | |
| TCGA | LCE3C | 353144 | 39 | 3 | 54 |
Total number of gains: 118; Total number of losses: 11; Total Number of normals: 359.
Somatic mutations of LCE3C:
Generating mutation plots.
Highly correlated genes for LCE3C:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCE3C | LCE3D | 0.913146 | 3 | 0 | 3 |
| LCE3C | LCE3A | 0.903419 | 3 | 0 | 3 |
| LCE3C | LCE3B | 0.880181 | 3 | 0 | 3 |
| LCE3C | LCE3E | 0.876527 | 3 | 0 | 3 |
| LCE3C | KRTAP20-3 | 0.668235 | 3 | 0 | 3 |
| LCE3C | GSDMA | 0.646626 | 3 | 0 | 3 |
| LCE3C | GPR45 | 0.607921 | 3 | 0 | 3 |
| LCE3C | TREX2 | 0.605025 | 3 | 0 | 3 |
| LCE3C | KLK4 | 0.596709 | 3 | 0 | 3 |
| LCE3C | SPRR2G | 0.594345 | 3 | 0 | 3 |
| LCE3C | KLK7 | 0.593339 | 3 | 0 | 3 |
| LCE3C | ALOX12B | 0.585096 | 3 | 0 | 3 |
| LCE3C | SPRR1A | 0.577704 | 3 | 0 | 3 |
| LCE3C | KRT80 | 0.559993 | 3 | 0 | 3 |
| LCE3C | PI3 | 0.538412 | 3 | 0 | 3 |
| LCE3C | DMKN | 0.536468 | 3 | 0 | 3 |
For details and further investigation, click here
