LCE3E

 

Full name: late cornified envelope 3E Alias Symbol: LEP17
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 353145 HGNC ID: HGNC:29463 Ensembl Gene: ENSG00000185966 OMIM ID: 612617
Drug and gene relationship at DGIdb

 

Expression of LCE3E:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 LCE3E 353145 49231 -0.1520 0.6926
GSE53624 LCE3E 353145 49231 -0.7824 0.0004
GSE97050 LCE3E 353145 A_33_P3264179 1.0584 0.2209
SRP007169 LCE3E 353145 RNAseq -7.3646 0.0002
SRP064894 LCE3E 353145 RNAseq -0.8704 0.3650
SRP133303 LCE3E 353145 RNAseq 0.4933 0.6703
SRP159526 LCE3E 353145 RNAseq -1.8641 0.3028
TCGA LCE3E 353145 RNAseq 1.4558 0.0380

Upregulated datasets: 1; Downregulated datasets: 1.  

 

Survival by LCE3E expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LCE3E:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LCE3E 353145 14 0 16
GSE20123 LCE3E 353145 14 0 16
GSE43470 LCE3E 353145 6 2 35
GSE46452 LCE3E 353145 2 1 56
GSE47630 LCE3E 353145 15 0 25
GSE54993 LCE3E 353145 0 4 66
GSE54994 LCE3E 353145 15 0 38
GSE60625 LCE3E 353145 0 0 11
GSE74703 LCE3E 353145 6 1 29
GSE74704 LCE3E 353145 7 0 13
TCGA LCE3E 353145 39 3 54

Total number of gains: 118; Total number of losses: 11; Total Number of normals: 359.  

 

Somatic mutations of LCE3E:

 

Generating mutation plots.

 

Highly correlated genes for LCE3E:

 

Showing top 20/63 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LCE3ELCE3A0.924298404
LCE3ELCE3D0.880021404
LCE3ELCE3C0.876527303
LCE3ELCE3B0.866092303
LCE3EALOX12B0.729851404
LCE3EPLA2G4D0.714864404
LCE3ESPRR2G0.688093404
LCE3ES100A120.676061303
LCE3EHMGB40.662902303
LCE3EGPR450.661846303
LCE3EALOXE30.659563403
LCE3EKLK40.655533303
LCE3EKLK70.652892403
LCE3EWFDC50.650234404
LCE3ESPRR1B0.643048404
LCE3ESBSN0.640161404
LCE3EDCD0.634165303
LCE3ESLC15A10.633126303
LCE3ESPRR2B0.63281303
LCE3EWFDC120.627409403

For details and further investigation, click here