| Full name: late cornified envelope 3A | Alias Symbol: LEP13 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 353142 | HGNC ID: HGNC:29461 | Ensembl Gene: ENSG00000185962 | OMIM ID: 612613 |
| Drug and gene relationship at DGIdb | |||
Expression of LCE3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | LCE3A | 353142 | 26937 | -0.1006 | 0.7908 | |
| GSE53624 | LCE3A | 353142 | 26937 | -0.5960 | 0.0062 | |
| GSE97050 | LCE3A | 353142 | A_23_P369471 | 0.7819 | 0.3524 | |
| TCGA | LCE3A | 353142 | RNAseq | 1.6897 | 0.0880 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LCE3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LCE3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCE3A | 353142 | 14 | 0 | 16 | |
| GSE20123 | LCE3A | 353142 | 14 | 0 | 16 | |
| GSE43470 | LCE3A | 353142 | 6 | 2 | 35 | |
| GSE46452 | LCE3A | 353142 | 3 | 1 | 55 | |
| GSE47630 | LCE3A | 353142 | 15 | 0 | 25 | |
| GSE54993 | LCE3A | 353142 | 0 | 4 | 66 | |
| GSE54994 | LCE3A | 353142 | 15 | 0 | 38 | |
| GSE60625 | LCE3A | 353142 | 0 | 0 | 11 | |
| GSE74703 | LCE3A | 353142 | 6 | 1 | 29 | |
| GSE74704 | LCE3A | 353142 | 7 | 0 | 13 | |
| TCGA | LCE3A | 353142 | 39 | 3 | 54 |
Total number of gains: 119; Total number of losses: 11; Total Number of normals: 358.
Somatic mutations of LCE3A:
Generating mutation plots.
Highly correlated genes for LCE3A:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCE3A | LCE3E | 0.924298 | 4 | 0 | 4 |
| LCE3A | LCE3C | 0.903419 | 3 | 0 | 3 |
| LCE3A | LCE3D | 0.853861 | 4 | 0 | 4 |
| LCE3A | LCE3B | 0.765673 | 4 | 0 | 3 |
| LCE3A | PLA2G4D | 0.648265 | 4 | 0 | 4 |
| LCE3A | ALOX12B | 0.647574 | 4 | 0 | 3 |
| LCE3A | KRTAP20-3 | 0.642533 | 3 | 0 | 3 |
| LCE3A | GPR45 | 0.640282 | 3 | 0 | 3 |
| LCE3A | SPRR2G | 0.639255 | 4 | 0 | 4 |
| LCE3A | KRT6B | 0.636726 | 3 | 0 | 3 |
| LCE3A | GSDMA | 0.621904 | 4 | 0 | 4 |
| LCE3A | HMGB4 | 0.619638 | 3 | 0 | 3 |
| LCE3A | WFDC5 | 0.615582 | 4 | 0 | 3 |
| LCE3A | WFDC12 | 0.607778 | 4 | 0 | 3 |
| LCE3A | ALOXE3 | 0.595649 | 4 | 0 | 3 |
| LCE3A | KLK7 | 0.594674 | 4 | 0 | 3 |
| LCE3A | SPRR1A | 0.591063 | 3 | 0 | 3 |
| LCE3A | RNASE7 | 0.580827 | 3 | 0 | 3 |
| LCE3A | SPRR2A | 0.579443 | 3 | 0 | 3 |
| LCE3A | DCD | 0.577822 | 3 | 0 | 3 |
For details and further investigation, click here
