| Full name: LIM domain binding 2 | Alias Symbol: CLIM1|LDB1 | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 9079 | HGNC ID: HGNC:6533 | Ensembl Gene: ENSG00000169744 | OMIM ID: 603450 |
| Drug and gene relationship at DGIdb | |||
Expression of LDB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LDB2 | 9079 | 206481_s_at | -0.9389 | 0.1315 | |
| GSE20347 | LDB2 | 9079 | 206481_s_at | -0.2777 | 0.1155 | |
| GSE23400 | LDB2 | 9079 | 206481_s_at | -0.2317 | 0.0183 | |
| GSE26886 | LDB2 | 9079 | 206481_s_at | -0.1841 | 0.5384 | |
| GSE29001 | LDB2 | 9079 | 206481_s_at | -0.4938 | 0.0502 | |
| GSE38129 | LDB2 | 9079 | 206481_s_at | -0.7570 | 0.0133 | |
| GSE45670 | LDB2 | 9079 | 206481_s_at | -1.7408 | 0.0001 | |
| GSE53622 | LDB2 | 9079 | 52244 | -0.5182 | 0.0000 | |
| GSE53624 | LDB2 | 9079 | 52244 | -0.4073 | 0.0000 | |
| GSE63941 | LDB2 | 9079 | 206481_s_at | -4.1331 | 0.0000 | |
| GSE77861 | LDB2 | 9079 | 206481_s_at | 0.2966 | 0.2745 | |
| GSE97050 | LDB2 | 9079 | A_33_P3300837 | -0.0540 | 0.8845 | |
| SRP007169 | LDB2 | 9079 | RNAseq | 0.7402 | 0.1222 | |
| SRP008496 | LDB2 | 9079 | RNAseq | 1.2720 | 0.0037 | |
| SRP064894 | LDB2 | 9079 | RNAseq | 0.0232 | 0.9455 | |
| SRP133303 | LDB2 | 9079 | RNAseq | -0.8364 | 0.0026 | |
| SRP159526 | LDB2 | 9079 | RNAseq | -0.4007 | 0.2987 | |
| SRP193095 | LDB2 | 9079 | RNAseq | 0.2818 | 0.2984 | |
| SRP219564 | LDB2 | 9079 | RNAseq | 0.0541 | 0.9262 | |
| TCGA | LDB2 | 9079 | RNAseq | -0.6223 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by LDB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LDB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LDB2 | 9079 | 0 | 18 | 12 | |
| GSE20123 | LDB2 | 9079 | 0 | 18 | 12 | |
| GSE43470 | LDB2 | 9079 | 1 | 15 | 27 | |
| GSE46452 | LDB2 | 9079 | 1 | 36 | 22 | |
| GSE47630 | LDB2 | 9079 | 1 | 19 | 20 | |
| GSE54993 | LDB2 | 9079 | 9 | 0 | 61 | |
| GSE54994 | LDB2 | 9079 | 4 | 12 | 37 | |
| GSE60625 | LDB2 | 9079 | 0 | 0 | 11 | |
| GSE74703 | LDB2 | 9079 | 1 | 13 | 22 | |
| GSE74704 | LDB2 | 9079 | 0 | 10 | 10 | |
| TCGA | LDB2 | 9079 | 9 | 48 | 39 |
Total number of gains: 26; Total number of losses: 189; Total Number of normals: 273.
Somatic mutations of LDB2:
Generating mutation plots.
Highly correlated genes for LDB2:
Showing top 20/368 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LDB2 | GPR146 | 0.815781 | 3 | 0 | 3 |
| LDB2 | ACKR4 | 0.806265 | 3 | 0 | 3 |
| LDB2 | ALDH8A1 | 0.771849 | 3 | 0 | 3 |
| LDB2 | TBX5-AS1 | 0.771734 | 3 | 0 | 3 |
| LDB2 | LINC01279 | 0.766812 | 4 | 0 | 4 |
| LDB2 | ARHGAP6 | 0.743859 | 9 | 0 | 8 |
| LDB2 | MAGI2-AS3 | 0.74057 | 6 | 0 | 5 |
| LDB2 | TMEM47 | 0.735542 | 11 | 0 | 11 |
| LDB2 | FAT4 | 0.734602 | 12 | 0 | 12 |
| LDB2 | BAHCC1 | 0.727815 | 3 | 0 | 3 |
| LDB2 | JAM2 | 0.70923 | 12 | 0 | 11 |
| LDB2 | ACTC1 | 0.707036 | 7 | 0 | 7 |
| LDB2 | ZFPM2 | 0.707008 | 7 | 0 | 6 |
| LDB2 | ENTPD1 | 0.704396 | 11 | 0 | 10 |
| LDB2 | CCDC69 | 0.703486 | 8 | 0 | 8 |
| LDB2 | MIR100HG | 0.703346 | 7 | 0 | 7 |
| LDB2 | LINC00968 | 0.701978 | 4 | 0 | 3 |
| LDB2 | MICU3 | 0.699706 | 4 | 0 | 3 |
| LDB2 | VASH2 | 0.698628 | 3 | 0 | 3 |
| LDB2 | ADAMTS9-AS2 | 0.698004 | 5 | 0 | 5 |
For details and further investigation, click here
