| Full name: ectonucleoside triphosphate diphosphohydrolase 1 | Alias Symbol: NTPDase-1|ATPDase|SPG64 | ||
| Type: protein-coding gene | Cytoband: 10q24.1 | ||
| Entrez ID: 953 | HGNC ID: HGNC:3363 | Ensembl Gene: ENSG00000138185 | OMIM ID: 601752 |
| Drug and gene relationship at DGIdb | |||
Expression of ENTPD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENTPD1 | 953 | 209473_at | -0.3594 | 0.6867 | |
| GSE20347 | ENTPD1 | 953 | 209473_at | 0.1578 | 0.2264 | |
| GSE23400 | ENTPD1 | 953 | 209473_at | 0.0103 | 0.9332 | |
| GSE26886 | ENTPD1 | 953 | 209473_at | 0.4425 | 0.1021 | |
| GSE29001 | ENTPD1 | 953 | 209473_at | 0.2475 | 0.3223 | |
| GSE38129 | ENTPD1 | 953 | 209473_at | -0.1362 | 0.5329 | |
| GSE45670 | ENTPD1 | 953 | 209473_at | -0.6420 | 0.0241 | |
| GSE53622 | ENTPD1 | 953 | 45546 | 0.1506 | 0.0369 | |
| GSE53624 | ENTPD1 | 953 | 45546 | 0.5087 | 0.0000 | |
| GSE63941 | ENTPD1 | 953 | 209473_at | -3.5001 | 0.0000 | |
| GSE77861 | ENTPD1 | 953 | 209473_at | 0.3134 | 0.1323 | |
| GSE97050 | ENTPD1 | 953 | A_33_P3262580 | 0.1633 | 0.4634 | |
| SRP007169 | ENTPD1 | 953 | RNAseq | 1.5935 | 0.0016 | |
| SRP008496 | ENTPD1 | 953 | RNAseq | 1.6909 | 0.0000 | |
| SRP064894 | ENTPD1 | 953 | RNAseq | 0.2703 | 0.2696 | |
| SRP133303 | ENTPD1 | 953 | RNAseq | 0.0880 | 0.6173 | |
| SRP159526 | ENTPD1 | 953 | RNAseq | 0.1981 | 0.6638 | |
| SRP193095 | ENTPD1 | 953 | RNAseq | 0.5572 | 0.0000 | |
| SRP219564 | ENTPD1 | 953 | RNAseq | 0.5855 | 0.1924 | |
| TCGA | ENTPD1 | 953 | RNAseq | -0.1365 | 0.0324 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by ENTPD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENTPD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENTPD1 | 953 | 0 | 8 | 22 | |
| GSE20123 | ENTPD1 | 953 | 0 | 7 | 23 | |
| GSE43470 | ENTPD1 | 953 | 0 | 7 | 36 | |
| GSE46452 | ENTPD1 | 953 | 0 | 11 | 48 | |
| GSE47630 | ENTPD1 | 953 | 2 | 14 | 24 | |
| GSE54993 | ENTPD1 | 953 | 7 | 0 | 63 | |
| GSE54994 | ENTPD1 | 953 | 2 | 10 | 41 | |
| GSE60625 | ENTPD1 | 953 | 0 | 0 | 11 | |
| GSE74703 | ENTPD1 | 953 | 0 | 5 | 31 | |
| GSE74704 | ENTPD1 | 953 | 0 | 4 | 16 | |
| TCGA | ENTPD1 | 953 | 6 | 27 | 63 |
Total number of gains: 17; Total number of losses: 93; Total Number of normals: 378.
Somatic mutations of ENTPD1:
Generating mutation plots.
Highly correlated genes for ENTPD1:
Showing top 20/222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENTPD1 | SHC3 | 0.747456 | 4 | 0 | 3 |
| ENTPD1 | LINC01279 | 0.744163 | 4 | 0 | 4 |
| ENTPD1 | SLC35G1 | 0.734131 | 3 | 0 | 3 |
| ENTPD1 | PTGDS | 0.731265 | 6 | 0 | 6 |
| ENTPD1 | FBXO17 | 0.72146 | 3 | 0 | 3 |
| ENTPD1 | ATOH8 | 0.712659 | 3 | 0 | 3 |
| ENTPD1 | DNM3OS | 0.711058 | 4 | 0 | 3 |
| ENTPD1 | GALNT15 | 0.709699 | 3 | 0 | 3 |
| ENTPD1 | ATP8A2 | 0.709263 | 3 | 0 | 3 |
| ENTPD1 | ACTA2 | 0.707619 | 9 | 0 | 8 |
| ENTPD1 | LDB2 | 0.704396 | 11 | 0 | 10 |
| ENTPD1 | CYP39A1 | 0.692986 | 3 | 0 | 3 |
| ENTPD1 | SCN3A | 0.690803 | 6 | 0 | 4 |
| ENTPD1 | LINC01082 | 0.689709 | 3 | 0 | 3 |
| ENTPD1 | TTC28 | 0.688486 | 5 | 0 | 5 |
| ENTPD1 | RASSF1 | 0.683706 | 4 | 0 | 4 |
| ENTPD1 | ACTC1 | 0.680739 | 8 | 0 | 7 |
| ENTPD1 | MEF2C | 0.678084 | 12 | 0 | 10 |
| ENTPD1 | MFNG | 0.676683 | 4 | 0 | 4 |
| ENTPD1 | VCAM1 | 0.675704 | 10 | 0 | 7 |
For details and further investigation, click here
