| Full name: atypical chemokine receptor 4 | Alias Symbol: CCR11|CCBP2|VSHK1|CCX-CKR|PPR1 | ||
| Type: protein-coding gene | Cytoband: 3q22.1 | ||
| Entrez ID: 51554 | HGNC ID: HGNC:1611 | Ensembl Gene: ENSG00000129048 | OMIM ID: 606065 |
Expression of ACKR4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACKR4 | 51554 | 220351_at | -0.1534 | 0.7739 | |
| GSE20347 | ACKR4 | 51554 | 220351_at | 0.0483 | 0.5373 | |
| GSE23400 | ACKR4 | 51554 | 220351_at | 0.0671 | 0.3441 | |
| GSE26886 | ACKR4 | 51554 | 220351_at | -0.1638 | 0.6168 | |
| GSE29001 | ACKR4 | 51554 | 220351_at | 0.5787 | 0.3145 | |
| GSE38129 | ACKR4 | 51554 | 220351_at | -0.3902 | 0.0645 | |
| GSE45670 | ACKR4 | 51554 | 220351_at | -0.0053 | 0.9935 | |
| GSE53622 | ACKR4 | 51554 | 54644 | 0.5664 | 0.0001 | |
| GSE53624 | ACKR4 | 51554 | 54644 | 0.8628 | 0.0000 | |
| GSE63941 | ACKR4 | 51554 | 220351_at | -4.8275 | 0.0000 | |
| GSE77861 | ACKR4 | 51554 | 220351_at | 0.0239 | 0.8184 | |
| SRP007169 | ACKR4 | 51554 | RNAseq | 1.3239 | 0.0514 | |
| SRP064894 | ACKR4 | 51554 | RNAseq | 0.0012 | 0.9970 | |
| SRP133303 | ACKR4 | 51554 | RNAseq | 0.5336 | 0.0108 | |
| SRP159526 | ACKR4 | 51554 | RNAseq | 0.8246 | 0.2017 | |
| SRP193095 | ACKR4 | 51554 | RNAseq | -0.7183 | 0.0747 | |
| SRP219564 | ACKR4 | 51554 | RNAseq | 0.9394 | 0.1707 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ACKR4 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ACKR4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACKR4 | 51554 | 16 | 0 | 14 | |
| GSE20123 | ACKR4 | 51554 | 16 | 0 | 14 | |
| GSE43470 | ACKR4 | 51554 | 21 | 0 | 22 | |
| GSE46452 | ACKR4 | 51554 | 15 | 4 | 40 | |
| GSE47630 | ACKR4 | 51554 | 18 | 3 | 19 | |
| GSE54993 | ACKR4 | 51554 | 2 | 8 | 60 | |
| GSE54994 | ACKR4 | 51554 | 32 | 3 | 18 | |
| GSE60625 | ACKR4 | 51554 | 0 | 6 | 5 | |
| GSE74703 | ACKR4 | 51554 | 18 | 0 | 18 | |
| GSE74704 | ACKR4 | 51554 | 11 | 0 | 9 | |
| TCGA | ACKR4 | 51554 | 58 | 6 | 32 |
Total number of gains: 207; Total number of losses: 30; Total Number of normals: 251.
Somatic mutations of ACKR4:
Generating mutation plots.
Highly correlated genes for ACKR4:
Showing top 20/185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACKR4 | LDB2 | 0.806265 | 3 | 0 | 3 |
| ACKR4 | IL33 | 0.769995 | 3 | 0 | 3 |
| ACKR4 | FOXF1 | 0.738395 | 3 | 0 | 3 |
| ACKR4 | ANK2 | 0.730057 | 3 | 0 | 3 |
| ACKR4 | JAM3 | 0.706738 | 3 | 0 | 3 |
| ACKR4 | DPP4 | 0.695122 | 4 | 0 | 4 |
| ACKR4 | AGTR1 | 0.686564 | 4 | 0 | 3 |
| ACKR4 | TOR1AIP1 | 0.675558 | 3 | 0 | 3 |
| ACKR4 | WFDC1 | 0.671209 | 4 | 0 | 4 |
| ACKR4 | RARRES2 | 0.667198 | 5 | 0 | 5 |
| ACKR4 | SYNC | 0.660841 | 4 | 0 | 3 |
| ACKR4 | LRRC17 | 0.659428 | 6 | 0 | 5 |
| ACKR4 | ANGPTL2 | 0.658261 | 5 | 0 | 3 |
| ACKR4 | NEK1 | 0.653277 | 3 | 0 | 3 |
| ACKR4 | LPP | 0.652916 | 3 | 0 | 3 |
| ACKR4 | BHMT2 | 0.651771 | 4 | 0 | 3 |
| ACKR4 | LMO3 | 0.647757 | 3 | 0 | 3 |
| ACKR4 | HSPB7 | 0.647714 | 3 | 0 | 3 |
| ACKR4 | PRUNE2 | 0.645013 | 3 | 0 | 3 |
| ACKR4 | KCNJ8 | 0.644515 | 5 | 0 | 4 |
For details and further investigation, click here
