| Full name: zinc finger protein, FOG family member 2 | Alias Symbol: FOG2|hFOG-2|ZNF89B|ZC2HC11B | ||
| Type: protein-coding gene | Cytoband: 8q23 | ||
| Entrez ID: 23414 | HGNC ID: HGNC:16700 | Ensembl Gene: ENSG00000169946 | OMIM ID: 603693 |
| Drug and gene relationship at DGIdb | |||
Expression of ZFPM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFPM2 | 23414 | 219778_at | -1.2432 | 0.3970 | |
| GSE20347 | ZFPM2 | 23414 | 219778_at | 0.3961 | 0.2758 | |
| GSE23400 | ZFPM2 | 23414 | 219778_at | -0.2071 | 0.2315 | |
| GSE26886 | ZFPM2 | 23414 | 219778_at | 1.0936 | 0.0220 | |
| GSE29001 | ZFPM2 | 23414 | 219778_at | 0.1656 | 0.6461 | |
| GSE38129 | ZFPM2 | 23414 | 219778_at | -0.3624 | 0.4462 | |
| GSE45670 | ZFPM2 | 23414 | 219778_at | -3.6231 | 0.0000 | |
| GSE53622 | ZFPM2 | 23414 | 75233 | -0.4344 | 0.0158 | |
| GSE53624 | ZFPM2 | 23414 | 75233 | -0.2200 | 0.1800 | |
| GSE63941 | ZFPM2 | 23414 | 219778_at | -6.3174 | 0.0000 | |
| GSE77861 | ZFPM2 | 23414 | 219778_at | 0.0938 | 0.5475 | |
| GSE97050 | ZFPM2 | 23414 | A_23_P168909 | -0.5001 | 0.2763 | |
| SRP007169 | ZFPM2 | 23414 | RNAseq | 2.4135 | 0.0046 | |
| SRP064894 | ZFPM2 | 23414 | RNAseq | -0.1334 | 0.7225 | |
| SRP133303 | ZFPM2 | 23414 | RNAseq | 0.1085 | 0.7097 | |
| SRP159526 | ZFPM2 | 23414 | RNAseq | -0.5853 | 0.1164 | |
| SRP193095 | ZFPM2 | 23414 | RNAseq | 2.2660 | 0.0000 | |
| SRP219564 | ZFPM2 | 23414 | RNAseq | 0.0285 | 0.9691 | |
| TCGA | ZFPM2 | 23414 | RNAseq | -0.4791 | 0.0167 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by ZFPM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFPM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFPM2 | 23414 | 16 | 0 | 14 | |
| GSE20123 | ZFPM2 | 23414 | 17 | 0 | 13 | |
| GSE43470 | ZFPM2 | 23414 | 22 | 0 | 21 | |
| GSE46452 | ZFPM2 | 23414 | 24 | 0 | 35 | |
| GSE47630 | ZFPM2 | 23414 | 24 | 0 | 16 | |
| GSE54993 | ZFPM2 | 23414 | 0 | 20 | 50 | |
| GSE54994 | ZFPM2 | 23414 | 37 | 1 | 15 | |
| GSE60625 | ZFPM2 | 23414 | 0 | 4 | 7 | |
| GSE74703 | ZFPM2 | 23414 | 19 | 0 | 17 | |
| GSE74704 | ZFPM2 | 23414 | 11 | 0 | 9 | |
| TCGA | ZFPM2 | 23414 | 60 | 1 | 35 |
Total number of gains: 230; Total number of losses: 26; Total Number of normals: 232.
Somatic mutations of ZFPM2:
Generating mutation plots.
Highly correlated genes for ZFPM2:
Showing top 20/1008 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFPM2 | PABPC5 | 0.788263 | 5 | 0 | 5 |
| ZFPM2 | SMAD9 | 0.78205 | 7 | 0 | 7 |
| ZFPM2 | FBXL7 | 0.781902 | 9 | 0 | 9 |
| ZFPM2 | LINC01279 | 0.777428 | 4 | 0 | 4 |
| ZFPM2 | NEGR1 | 0.772887 | 6 | 0 | 6 |
| ZFPM2 | TMEM178A | 0.770514 | 4 | 0 | 4 |
| ZFPM2 | SGCD | 0.769451 | 8 | 0 | 7 |
| ZFPM2 | RSPO3 | 0.765002 | 7 | 0 | 7 |
| ZFPM2 | LRRN4CL | 0.758981 | 7 | 0 | 7 |
| ZFPM2 | NAP1L3 | 0.75789 | 9 | 0 | 8 |
| ZFPM2 | ADAMTS5 | 0.754993 | 9 | 0 | 9 |
| ZFPM2 | LDLRAD4 | 0.754153 | 3 | 0 | 3 |
| ZFPM2 | ZBTB20 | 0.75351 | 7 | 0 | 6 |
| ZFPM2 | AGTR1 | 0.748748 | 9 | 0 | 8 |
| ZFPM2 | MIR100HG | 0.74509 | 5 | 0 | 5 |
| ZFPM2 | C16orf89 | 0.744284 | 3 | 0 | 3 |
| ZFPM2 | HMCN1 | 0.742669 | 8 | 0 | 8 |
| ZFPM2 | FAT4 | 0.742139 | 7 | 0 | 6 |
| ZFPM2 | ANK2 | 0.741088 | 8 | 0 | 7 |
| ZFPM2 | NEXN | 0.740933 | 7 | 0 | 6 |
For details and further investigation, click here
