TBX5-AS1

 

Full name: TBX5 antisense RNA 1 Alias Symbol: 
Type: non-coding RNA Cytoband: 12q24.21
Entrez ID: 255480 HGNC ID: HGNC:27402 Ensembl Gene: ENSG00000255399 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TBX5-AS1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TBX5-AS1 255480 239919_at -0.4464 0.4364
GSE26886 TBX5-AS1 255480 239919_at 0.3114 0.0313
GSE45670 TBX5-AS1 255480 239919_at -0.9249 0.0000
GSE53622 TBX5-AS1 255480 115061 -0.0688 0.7853
GSE53624 TBX5-AS1 255480 115061 0.3925 0.0023
GSE63941 TBX5-AS1 255480 239919_at -4.4832 0.0000
GSE77861 TBX5-AS1 255480 233947_s_at -0.0151 0.8883
SRP064894 TBX5-AS1 255480 RNAseq 0.1654 0.6716
SRP133303 TBX5-AS1 255480 RNAseq 0.0557 0.8918
SRP159526 TBX5-AS1 255480 RNAseq 0.2066 0.6968
SRP219564 TBX5-AS1 255480 RNAseq -0.2321 0.8235

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by TBX5-AS1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of TBX5-AS1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TBX5-AS1 255480 4 3 23
GSE20123 TBX5-AS1 255480 4 3 23
GSE43470 TBX5-AS1 255480 2 0 41
GSE46452 TBX5-AS1 255480 9 1 49
GSE47630 TBX5-AS1 255480 9 3 28
GSE54993 TBX5-AS1 255480 0 5 65
GSE54994 TBX5-AS1 255480 6 5 42
GSE60625 TBX5-AS1 255480 0 0 11
GSE74703 TBX5-AS1 255480 2 0 34
GSE74704 TBX5-AS1 255480 2 2 16

Total number of gains: 38; Total number of losses: 22; Total Number of normals: 332.  


 

Somatic mutations of TBX5-AS1:

 

Generating mutation plots.

 

Highly correlated genes for TBX5-AS1:

 

Showing top 20/540 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TBX5-AS1GFRA10.860221303
TBX5-AS1MGARP0.853271303
TBX5-AS1RCAN20.852307303
TBX5-AS1CNTN30.835337303
TBX5-AS1PEG30.809786303
TBX5-AS1PCDH90.806876404
TBX5-AS1TIMP30.804535303
TBX5-AS1SGCD0.80403505
TBX5-AS1GREM20.801214303
TBX5-AS1ITGBL10.78783403
TBX5-AS1FYCO10.786178303
TBX5-AS1S1PR10.782909303
TBX5-AS1NAP1L30.781057505
TBX5-AS1MRVI10.775254404
TBX5-AS1LDB20.771734303
TBX5-AS1TBX50.770406706
TBX5-AS1ZBTB470.766355303
TBX5-AS1GYPC0.760619403
TBX5-AS1LINC012790.757339404
TBX5-AS1PRKG10.75428505

For details and further investigation, click here