| Full name: mediator complex subunit 13L | Alias Symbol: KIAA1025|TRAP240L | ||
| Type: protein-coding gene | Cytoband: 12q24.21 | ||
| Entrez ID: 23389 | HGNC ID: HGNC:22962 | Ensembl Gene: ENSG00000123066 | OMIM ID: 608771 |
| Drug and gene relationship at DGIdb | |||
Expression of MED13L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED13L | 23389 | 212209_at | 0.1374 | 0.6898 | |
| GSE20347 | MED13L | 23389 | 212208_at | 0.0354 | 0.8071 | |
| GSE23400 | MED13L | 23389 | 212209_at | 0.1943 | 0.0025 | |
| GSE26886 | MED13L | 23389 | 212208_at | -0.3887 | 0.0839 | |
| GSE29001 | MED13L | 23389 | 212207_at | -0.0292 | 0.9252 | |
| GSE38129 | MED13L | 23389 | 212209_at | 0.0859 | 0.4513 | |
| GSE45670 | MED13L | 23389 | 212209_at | -0.0644 | 0.6387 | |
| GSE53622 | MED13L | 23389 | 33434 | -0.0032 | 0.9574 | |
| GSE53624 | MED13L | 23389 | 33434 | -0.1345 | 0.0082 | |
| GSE63941 | MED13L | 23389 | 212209_at | 0.1795 | 0.7006 | |
| GSE77861 | MED13L | 23389 | 212208_at | 0.3376 | 0.0296 | |
| GSE97050 | MED13L | 23389 | A_23_P47991 | -0.2445 | 0.2966 | |
| SRP007169 | MED13L | 23389 | RNAseq | 0.7396 | 0.0795 | |
| SRP008496 | MED13L | 23389 | RNAseq | 0.8842 | 0.0002 | |
| SRP064894 | MED13L | 23389 | RNAseq | -0.3796 | 0.2000 | |
| SRP133303 | MED13L | 23389 | RNAseq | -0.1050 | 0.3335 | |
| SRP159526 | MED13L | 23389 | RNAseq | -0.0364 | 0.8548 | |
| SRP193095 | MED13L | 23389 | RNAseq | 0.0327 | 0.6882 | |
| SRP219564 | MED13L | 23389 | RNAseq | -0.4382 | 0.2334 | |
| TCGA | MED13L | 23389 | RNAseq | -0.0718 | 0.1153 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MED13L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MED13L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED13L | 23389 | 4 | 3 | 23 | |
| GSE20123 | MED13L | 23389 | 4 | 3 | 23 | |
| GSE43470 | MED13L | 23389 | 2 | 0 | 41 | |
| GSE46452 | MED13L | 23389 | 9 | 1 | 49 | |
| GSE47630 | MED13L | 23389 | 9 | 3 | 28 | |
| GSE54993 | MED13L | 23389 | 0 | 5 | 65 | |
| GSE54994 | MED13L | 23389 | 6 | 5 | 42 | |
| GSE60625 | MED13L | 23389 | 0 | 0 | 11 | |
| GSE74703 | MED13L | 23389 | 2 | 0 | 34 | |
| GSE74704 | MED13L | 23389 | 2 | 2 | 16 | |
| TCGA | MED13L | 23389 | 22 | 12 | 62 |
Total number of gains: 60; Total number of losses: 34; Total Number of normals: 394.
Somatic mutations of MED13L:
Generating mutation plots.
Highly correlated genes for MED13L:
Showing all 15 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED13L | ZNF232 | 0.660985 | 3 | 0 | 3 |
| MED13L | ZNF157 | 0.660124 | 3 | 0 | 3 |
| MED13L | DYNC1I1 | 0.594832 | 4 | 0 | 3 |
| MED13L | SETD1B | 0.594117 | 5 | 0 | 3 |
| MED13L | CECR2 | 0.59374 | 4 | 0 | 3 |
| MED13L | TIGD7 | 0.58931 | 4 | 0 | 3 |
| MED13L | FAM171A1 | 0.571166 | 4 | 0 | 3 |
| MED13L | TXNL4B | 0.559717 | 3 | 0 | 3 |
| MED13L | AGO3 | 0.554822 | 4 | 0 | 3 |
| MED13L | ZNF337 | 0.554403 | 4 | 0 | 3 |
| MED13L | PRPF3 | 0.549893 | 3 | 0 | 3 |
| MED13L | CARD8 | 0.533233 | 5 | 0 | 3 |
| MED13L | CDK13 | 0.530196 | 5 | 0 | 3 |
| MED13L | ARID4B | 0.502352 | 5 | 0 | 3 |
| MED13L | DYRK1A | 0.500738 | 6 | 0 | 3 |
For details and further investigation, click here
