| Full name: argonaute RISC catalytic component 3 | Alias Symbol: hAGO3|FLJ12765 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 192669 | HGNC ID: HGNC:18421 | Ensembl Gene: ENSG00000126070 | OMIM ID: 607355 |
Expression of AGO3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGO3 | 192669 | 219426_at | 0.2700 | 0.5869 | |
| GSE20347 | AGO3 | 192669 | 219426_at | 0.2397 | 0.1391 | |
| GSE23400 | AGO3 | 192669 | 219426_at | 0.3999 | 0.0000 | |
| GSE26886 | AGO3 | 192669 | 219426_at | 0.2540 | 0.3423 | |
| GSE29001 | AGO3 | 192669 | 219426_at | 0.5786 | 0.0719 | |
| GSE38129 | AGO3 | 192669 | 219426_at | 0.2707 | 0.2907 | |
| GSE45670 | AGO3 | 192669 | 219426_at | 0.6375 | 0.0020 | |
| GSE53622 | AGO3 | 192669 | 16275 | 0.3914 | 0.0000 | |
| GSE53624 | AGO3 | 192669 | 16275 | 0.5078 | 0.0000 | |
| GSE63941 | AGO3 | 192669 | 219426_at | 0.1184 | 0.8281 | |
| GSE77861 | AGO3 | 192669 | 219426_at | 0.5043 | 0.2467 | |
| SRP007169 | AGO3 | 192669 | RNAseq | 0.7916 | 0.0309 | |
| SRP008496 | AGO3 | 192669 | RNAseq | 0.9031 | 0.0001 | |
| SRP064894 | AGO3 | 192669 | RNAseq | 0.2781 | 0.1235 | |
| SRP133303 | AGO3 | 192669 | RNAseq | 0.2341 | 0.0320 | |
| SRP159526 | AGO3 | 192669 | RNAseq | 0.2656 | 0.4192 | |
| SRP193095 | AGO3 | 192669 | RNAseq | 0.4036 | 0.0002 | |
| SRP219564 | AGO3 | 192669 | RNAseq | -0.0639 | 0.8388 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AGO3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AGO3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGO3 | 192669 | 3 | 5 | 22 | |
| GSE20123 | AGO3 | 192669 | 2 | 4 | 24 | |
| GSE43470 | AGO3 | 192669 | 7 | 2 | 34 | |
| GSE46452 | AGO3 | 192669 | 4 | 1 | 54 | |
| GSE47630 | AGO3 | 192669 | 8 | 3 | 29 | |
| GSE54993 | AGO3 | 192669 | 1 | 1 | 68 | |
| GSE54994 | AGO3 | 192669 | 11 | 2 | 40 | |
| GSE60625 | AGO3 | 192669 | 0 | 0 | 11 | |
| GSE74703 | AGO3 | 192669 | 6 | 1 | 29 | |
| GSE74704 | AGO3 | 192669 | 1 | 0 | 19 | |
| TCGA | AGO3 | 192669 | 11 | 19 | 66 |
Total number of gains: 54; Total number of losses: 38; Total Number of normals: 396.
Somatic mutations of AGO3:
Generating mutation plots.
Highly correlated genes for AGO3:
Showing top 20/156 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGO3 | GNL3L | 0.686434 | 3 | 0 | 3 |
| AGO3 | DICER1 | 0.64572 | 3 | 0 | 3 |
| AGO3 | GPATCH2L | 0.645642 | 3 | 0 | 3 |
| AGO3 | ANKFY1 | 0.638289 | 3 | 0 | 3 |
| AGO3 | ZNF148 | 0.637216 | 5 | 0 | 4 |
| AGO3 | HOXC9 | 0.617387 | 3 | 0 | 3 |
| AGO3 | VGLL4 | 0.604371 | 5 | 0 | 3 |
| AGO3 | NPIPA1 | 0.599025 | 3 | 0 | 3 |
| AGO3 | ATM | 0.598528 | 3 | 0 | 3 |
| AGO3 | ESF1 | 0.596631 | 7 | 0 | 4 |
| AGO3 | MTF2 | 0.596238 | 5 | 0 | 4 |
| AGO3 | ALMS1 | 0.593435 | 5 | 0 | 5 |
| AGO3 | ZNF567 | 0.590325 | 4 | 0 | 3 |
| AGO3 | SUPT3H | 0.589186 | 4 | 0 | 4 |
| AGO3 | COA7 | 0.583474 | 5 | 0 | 4 |
| AGO3 | OTUD6B-AS1 | 0.581121 | 4 | 0 | 3 |
| AGO3 | ZNF124 | 0.580858 | 5 | 0 | 3 |
| AGO3 | AGO2 | 0.580775 | 7 | 0 | 6 |
| AGO3 | SMURF2 | 0.577824 | 6 | 0 | 4 |
| AGO3 | ZNF451 | 0.576027 | 4 | 0 | 3 |
For details and further investigation, click here
