| Full name: cyclin dependent kinase 13 | Alias Symbol: CHED|CDC2L|KIAA1791 | ||
| Type: protein-coding gene | Cytoband: 7p14.1 | ||
| Entrez ID: 8621 | HGNC ID: HGNC:1733 | Ensembl Gene: ENSG00000065883 | OMIM ID: 603309 |
| Drug and gene relationship at DGIdb | |||
Expression of CDK13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDK13 | 8621 | 232266_x_at | 0.2192 | 0.8045 | |
| GSE20347 | CDK13 | 8621 | 207318_s_at | -0.0234 | 0.8319 | |
| GSE23400 | CDK13 | 8621 | 207318_s_at | 0.0373 | 0.6636 | |
| GSE26886 | CDK13 | 8621 | 232266_x_at | 0.3277 | 0.2455 | |
| GSE29001 | CDK13 | 8621 | 207318_s_at | -0.1598 | 0.6276 | |
| GSE38129 | CDK13 | 8621 | 207318_s_at | 0.1133 | 0.3522 | |
| GSE45670 | CDK13 | 8621 | 232266_x_at | 0.2602 | 0.0767 | |
| GSE53622 | CDK13 | 8621 | 21613 | 0.0739 | 0.1633 | |
| GSE53624 | CDK13 | 8621 | 21613 | 0.0399 | 0.4542 | |
| GSE63941 | CDK13 | 8621 | 232266_x_at | -0.3186 | 0.2202 | |
| GSE77861 | CDK13 | 8621 | 232266_x_at | 0.8485 | 0.2005 | |
| GSE97050 | CDK13 | 8621 | A_33_P3329149 | -0.1564 | 0.5595 | |
| SRP007169 | CDK13 | 8621 | RNAseq | -0.3802 | 0.2114 | |
| SRP008496 | CDK13 | 8621 | RNAseq | 0.0275 | 0.9105 | |
| SRP064894 | CDK13 | 8621 | RNAseq | -0.2196 | 0.2352 | |
| SRP133303 | CDK13 | 8621 | RNAseq | 0.0517 | 0.6293 | |
| SRP159526 | CDK13 | 8621 | RNAseq | -0.2385 | 0.1488 | |
| SRP193095 | CDK13 | 8621 | RNAseq | -0.1780 | 0.0429 | |
| SRP219564 | CDK13 | 8621 | RNAseq | -0.2836 | 0.3336 | |
| TCGA | CDK13 | 8621 | RNAseq | 0.0343 | 0.4546 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDK13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDK13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDK13 | 8621 | 15 | 0 | 15 | |
| GSE20123 | CDK13 | 8621 | 14 | 0 | 16 | |
| GSE43470 | CDK13 | 8621 | 4 | 0 | 39 | |
| GSE46452 | CDK13 | 8621 | 11 | 1 | 47 | |
| GSE47630 | CDK13 | 8621 | 8 | 1 | 31 | |
| GSE54993 | CDK13 | 8621 | 0 | 7 | 63 | |
| GSE54994 | CDK13 | 8621 | 17 | 3 | 33 | |
| GSE60625 | CDK13 | 8621 | 0 | 0 | 11 | |
| GSE74703 | CDK13 | 8621 | 4 | 0 | 32 | |
| GSE74704 | CDK13 | 8621 | 8 | 0 | 12 | |
| TCGA | CDK13 | 8621 | 52 | 7 | 37 |
Total number of gains: 133; Total number of losses: 19; Total Number of normals: 336.
Somatic mutations of CDK13:
Generating mutation plots.
Highly correlated genes for CDK13:
Showing top 20/85 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDK13 | CMBL | 0.914181 | 5 | 0 | 5 |
| CDK13 | PGF | 0.856008 | 7 | 0 | 7 |
| CDK13 | ZNF611 | 0.828458 | 6 | 0 | 6 |
| CDK13 | UACA | 0.819754 | 4 | 0 | 4 |
| CDK13 | FUT8-AS1 | 0.817674 | 4 | 0 | 4 |
| CDK13 | TRMT10B | 0.815986 | 4 | 0 | 4 |
| CDK13 | ARHGEF1 | 0.794186 | 6 | 0 | 6 |
| CDK13 | TNRC6C-AS1 | 0.771482 | 5 | 0 | 5 |
| CDK13 | SSBP3-AS1 | 0.765719 | 5 | 0 | 5 |
| CDK13 | ZNF160 | 0.750542 | 9 | 0 | 7 |
| CDK13 | WDPCP | 0.741611 | 6 | 0 | 5 |
| CDK13 | WAC-AS1 | 0.737212 | 3 | 0 | 3 |
| CDK13 | KIFC2 | 0.726073 | 4 | 0 | 4 |
| CDK13 | PLA2G2C | 0.720894 | 3 | 0 | 3 |
| CDK13 | TMEM241 | 0.714209 | 4 | 0 | 4 |
| CDK13 | ANKRD10-IT1 | 0.700172 | 6 | 0 | 5 |
| CDK13 | TSR1 | 0.68422 | 5 | 0 | 4 |
| CDK13 | KRTAP10-12 | 0.678419 | 3 | 0 | 3 |
| CDK13 | STRC | 0.67794 | 3 | 0 | 3 |
| CDK13 | DCDC1 | 0.667496 | 3 | 0 | 3 |
For details and further investigation, click here
