ARID4B

 

Full name: AT-rich interaction domain 4B Alias Symbol: BCAA|BRCAA1|SAP180
Type: protein-coding gene Cytoband: 1q42.3
Entrez ID: 51742 HGNC ID: HGNC:15550 Ensembl Gene: ENSG00000054267 OMIM ID: 609696
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ARID4B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ARID4B 51742 221230_s_at 0.2220 0.2433
GSE20347 ARID4B 51742 221230_s_at 0.3778 0.0051
GSE23400 ARID4B 51742 221230_s_at 0.3260 0.0002
GSE26886 ARID4B 51742 221230_s_at -0.1575 0.5562
GSE29001 ARID4B 51742 221230_s_at 0.3727 0.2240
GSE38129 ARID4B 51742 221230_s_at 0.3082 0.0056
GSE45670 ARID4B 51742 221230_s_at 0.0267 0.8530
GSE53622 ARID4B 51742 142583 0.1249 0.0627
GSE53624 ARID4B 51742 142583 0.0274 0.7788
GSE63941 ARID4B 51742 221230_s_at -0.6688 0.1083
GSE77861 ARID4B 51742 221230_s_at 0.5871 0.0102
GSE97050 ARID4B 51742 A_23_P201951 0.0359 0.8987
SRP007169 ARID4B 51742 RNAseq 0.8843 0.0144
SRP008496 ARID4B 51742 RNAseq 1.0396 0.0000
SRP064894 ARID4B 51742 RNAseq -0.1385 0.5322
SRP133303 ARID4B 51742 RNAseq 0.2744 0.0006
SRP159526 ARID4B 51742 RNAseq 0.0086 0.9808
SRP193095 ARID4B 51742 RNAseq 0.1952 0.0460
SRP219564 ARID4B 51742 RNAseq -0.0888 0.7453
TCGA ARID4B 51742 RNAseq -0.0950 0.0601

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by ARID4B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ARID4B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ARID4B 51742 10 0 20
GSE20123 ARID4B 51742 11 0 19
GSE43470 ARID4B 51742 8 1 34
GSE46452 ARID4B 51742 4 2 53
GSE47630 ARID4B 51742 15 0 25
GSE54993 ARID4B 51742 0 6 64
GSE54994 ARID4B 51742 16 0 37
GSE60625 ARID4B 51742 0 0 11
GSE74703 ARID4B 51742 8 1 27
GSE74704 ARID4B 51742 5 0 15
TCGA ARID4B 51742 44 3 49

Total number of gains: 121; Total number of losses: 13; Total Number of normals: 354.  

 

Somatic mutations of ARID4B:

 

Generating mutation plots.

 

Highly correlated genes for ARID4B:

 

Showing top 20/212 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ARID4BPHF120.722282303
ARID4BMIR36820.646118403
ARID4BITGAV0.637499403
ARID4BPDCD110.63623303
ARID4BOSTM10.632757504
ARID4BCEP720.631866303
ARID4BPHF60.631566303
ARID4BANKLE20.631465404
ARID4BANKRD100.631298504
ARID4BFANCL0.627544604
ARID4BITPKB0.624733403
ARID4BTDG0.620176504
ARID4BSOX300.615946303
ARID4BSMARCAD10.613035404
ARID4BSP30.608201805
ARID4BCHST10.608056303
ARID4BZNF518B0.607282403
ARID4BDESI20.606164906
ARID4BHOXB70.605945403
ARID4BPHTF20.605922605

For details and further investigation, click here