| Full name: dynein cytoplasmic 1 intermediate chain 1 | Alias Symbol: DNCIC1 | ||
| Type: protein-coding gene | Cytoband: 7q21.3 | ||
| Entrez ID: 1780 | HGNC ID: HGNC:2963 | Ensembl Gene: ENSG00000158560 | OMIM ID: 603772 |
| Drug and gene relationship at DGIdb | |||
Expression of DYNC1I1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DYNC1I1 | 1780 | 205348_s_at | 1.0494 | 0.1116 | |
| GSE20347 | DYNC1I1 | 1780 | 205348_s_at | 1.1307 | 0.0000 | |
| GSE23400 | DYNC1I1 | 1780 | 205348_s_at | 0.3951 | 0.0000 | |
| GSE26886 | DYNC1I1 | 1780 | 205348_s_at | 1.9813 | 0.0018 | |
| GSE29001 | DYNC1I1 | 1780 | 205348_s_at | 1.0274 | 0.0011 | |
| GSE38129 | DYNC1I1 | 1780 | 205348_s_at | 0.9328 | 0.0000 | |
| GSE45670 | DYNC1I1 | 1780 | 205348_s_at | 0.2524 | 0.6268 | |
| GSE53622 | DYNC1I1 | 1780 | 15548 | 1.0262 | 0.0000 | |
| GSE53624 | DYNC1I1 | 1780 | 15548 | 1.4701 | 0.0000 | |
| GSE63941 | DYNC1I1 | 1780 | 205348_s_at | 0.8315 | 0.4249 | |
| GSE77861 | DYNC1I1 | 1780 | 205348_s_at | 0.9490 | 0.0026 | |
| GSE97050 | DYNC1I1 | 1780 | A_24_P221414 | -0.2616 | 0.4988 | |
| SRP007169 | DYNC1I1 | 1780 | RNAseq | 4.6686 | 0.0002 | |
| SRP064894 | DYNC1I1 | 1780 | RNAseq | 0.4265 | 0.2293 | |
| SRP133303 | DYNC1I1 | 1780 | RNAseq | 0.9640 | 0.0002 | |
| SRP159526 | DYNC1I1 | 1780 | RNAseq | 2.1598 | 0.0000 | |
| SRP219564 | DYNC1I1 | 1780 | RNAseq | 0.0008 | 0.9991 | |
| TCGA | DYNC1I1 | 1780 | RNAseq | 0.4461 | 0.0912 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by DYNC1I1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DYNC1I1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DYNC1I1 | 1780 | 13 | 0 | 17 | |
| GSE20123 | DYNC1I1 | 1780 | 13 | 0 | 17 | |
| GSE43470 | DYNC1I1 | 1780 | 8 | 1 | 34 | |
| GSE46452 | DYNC1I1 | 1780 | 12 | 0 | 47 | |
| GSE47630 | DYNC1I1 | 1780 | 8 | 2 | 30 | |
| GSE54993 | DYNC1I1 | 1780 | 1 | 9 | 60 | |
| GSE54994 | DYNC1I1 | 1780 | 16 | 3 | 34 | |
| GSE60625 | DYNC1I1 | 1780 | 0 | 5 | 6 | |
| GSE74703 | DYNC1I1 | 1780 | 7 | 1 | 28 | |
| GSE74704 | DYNC1I1 | 1780 | 9 | 0 | 11 | |
| TCGA | DYNC1I1 | 1780 | 55 | 4 | 37 |
Total number of gains: 142; Total number of losses: 25; Total Number of normals: 321.
Somatic mutations of DYNC1I1:
Generating mutation plots.
Highly correlated genes for DYNC1I1:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DYNC1I1 | HOXC9 | 0.699533 | 4 | 0 | 4 |
| DYNC1I1 | ANKRD53 | 0.692113 | 3 | 0 | 3 |
| DYNC1I1 | THNSL1 | 0.680346 | 5 | 0 | 5 |
| DYNC1I1 | NDUFB9 | 0.673803 | 4 | 0 | 4 |
| DYNC1I1 | FRS3 | 0.66854 | 3 | 0 | 3 |
| DYNC1I1 | ZNF697 | 0.662444 | 4 | 0 | 3 |
| DYNC1I1 | CD320 | 0.658564 | 5 | 0 | 4 |
| DYNC1I1 | DTX3 | 0.65065 | 3 | 0 | 3 |
| DYNC1I1 | FARP1 | 0.643794 | 10 | 0 | 9 |
| DYNC1I1 | MLF1 | 0.639615 | 9 | 0 | 8 |
| DYNC1I1 | OBSL1 | 0.638559 | 5 | 0 | 5 |
| DYNC1I1 | HAUS8 | 0.636426 | 4 | 0 | 4 |
| DYNC1I1 | SUPT6H | 0.635754 | 4 | 0 | 3 |
| DYNC1I1 | COL4A2 | 0.631267 | 9 | 0 | 8 |
| DYNC1I1 | ABTB1 | 0.630896 | 3 | 0 | 3 |
| DYNC1I1 | TP53BP1 | 0.628744 | 10 | 0 | 7 |
| DYNC1I1 | LBH | 0.628423 | 9 | 0 | 8 |
| DYNC1I1 | LAMTOR4 | 0.625837 | 6 | 0 | 4 |
| DYNC1I1 | ANKRD39 | 0.625693 | 6 | 0 | 5 |
| DYNC1I1 | OSGIN2 | 0.625241 | 6 | 0 | 5 |
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