| Full name: CECR2 histone acetyl-lysine reader | Alias Symbol: KIAA1740 | ||
| Type: protein-coding gene | Cytoband: 22q11.1-q11.21 | ||
| Entrez ID: 27443 | HGNC ID: HGNC:1840 | Ensembl Gene: ENSG00000099954 | OMIM ID: 607576 |
| Drug and gene relationship at DGIdb | |||
Expression of CECR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CECR2 | 27443 | 239752_at | 1.8327 | 0.1431 | |
| GSE26886 | CECR2 | 27443 | 223729_at | 0.3822 | 0.0540 | |
| GSE45670 | CECR2 | 27443 | 239752_at | 1.6599 | 0.0031 | |
| GSE53622 | CECR2 | 27443 | 149263 | 0.8139 | 0.0000 | |
| GSE53624 | CECR2 | 27443 | 149263 | 0.8104 | 0.0000 | |
| GSE63941 | CECR2 | 27443 | 239752_at | 1.6128 | 0.1553 | |
| GSE77861 | CECR2 | 27443 | 239752_at | 0.7580 | 0.0331 | |
| GSE97050 | CECR2 | 27443 | A_33_P3349395 | 0.0309 | 0.9149 | |
| SRP064894 | CECR2 | 27443 | RNAseq | 1.6923 | 0.0001 | |
| SRP133303 | CECR2 | 27443 | RNAseq | 1.6647 | 0.0000 | |
| SRP159526 | CECR2 | 27443 | RNAseq | 2.8787 | 0.0000 | |
| SRP193095 | CECR2 | 27443 | RNAseq | 1.6394 | 0.0000 | |
| SRP219564 | CECR2 | 27443 | RNAseq | 0.9943 | 0.0832 | |
| TCGA | CECR2 | 27443 | RNAseq | 1.1601 | 0.0006 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by CECR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CECR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CECR2 | 27443 | 5 | 7 | 18 | |
| GSE20123 | CECR2 | 27443 | 5 | 7 | 18 | |
| GSE43470 | CECR2 | 27443 | 5 | 7 | 31 | |
| GSE46452 | CECR2 | 27443 | 32 | 2 | 25 | |
| GSE47630 | CECR2 | 27443 | 8 | 5 | 27 | |
| GSE54993 | CECR2 | 27443 | 2 | 7 | 61 | |
| GSE54994 | CECR2 | 27443 | 12 | 7 | 34 | |
| GSE60625 | CECR2 | 27443 | 5 | 0 | 6 | |
| GSE74703 | CECR2 | 27443 | 5 | 5 | 26 | |
| GSE74704 | CECR2 | 27443 | 2 | 4 | 14 | |
| TCGA | CECR2 | 27443 | 25 | 17 | 54 |
Total number of gains: 106; Total number of losses: 68; Total Number of normals: 314.
Somatic mutations of CECR2:
Generating mutation plots.
Highly correlated genes for CECR2:
Showing top 20/160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CECR2 | BAX | 0.789332 | 3 | 0 | 3 |
| CECR2 | UBE2I | 0.772116 | 3 | 0 | 3 |
| CECR2 | WNT1 | 0.736897 | 3 | 0 | 3 |
| CECR2 | MAP7D2 | 0.718274 | 4 | 0 | 4 |
| CECR2 | CCL26 | 0.690029 | 3 | 0 | 3 |
| CECR2 | BMP8B | 0.688843 | 4 | 0 | 3 |
| CECR2 | RASL11B | 0.683315 | 4 | 0 | 4 |
| CECR2 | TNFAIP8L1 | 0.679296 | 4 | 0 | 4 |
| CECR2 | WRNIP1 | 0.670184 | 3 | 0 | 3 |
| CECR2 | DHX9 | 0.665718 | 6 | 0 | 5 |
| CECR2 | MDC1 | 0.66479 | 4 | 0 | 3 |
| CECR2 | APTX | 0.664657 | 5 | 0 | 3 |
| CECR2 | ZNF182 | 0.663882 | 3 | 0 | 3 |
| CECR2 | SYT1 | 0.660716 | 4 | 0 | 4 |
| CECR2 | OSBPL11 | 0.657474 | 4 | 0 | 3 |
| CECR2 | TOR3A | 0.657459 | 3 | 0 | 3 |
| CECR2 | SLC27A5 | 0.655678 | 5 | 0 | 4 |
| CECR2 | WRAP73 | 0.64929 | 4 | 0 | 3 |
| CECR2 | PGP | 0.646754 | 4 | 0 | 3 |
| CECR2 | LRRC4 | 0.641027 | 4 | 0 | 3 |
For details and further investigation, click here
