TXNL4B

 

Full name: thioredoxin like 4B Alias Symbol: FLJ20511|DLP|Dim2
Type: protein-coding gene Cytoband: 16q22.2
Entrez ID: 54957 HGNC ID: HGNC:26041 Ensembl Gene: ENSG00000140830 OMIM ID: 617722
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TXNL4B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TXNL4B 54957 218794_s_at 0.4864 0.1193
GSE20347 TXNL4B 54957 218794_s_at 0.4263 0.0002
GSE23400 TXNL4B 54957 218794_s_at 0.0543 0.2411
GSE26886 TXNL4B 54957 218794_s_at 0.6260 0.0001
GSE29001 TXNL4B 54957 218794_s_at 0.2615 0.0833
GSE38129 TXNL4B 54957 218794_s_at 0.5029 0.0000
GSE45670 TXNL4B 54957 218794_s_at 0.5014 0.0000
GSE53622 TXNL4B 54957 112405 0.2864 0.0008
GSE53624 TXNL4B 54957 112405 0.3899 0.0001
GSE63941 TXNL4B 54957 218794_s_at 0.6964 0.0812
GSE77861 TXNL4B 54957 218794_s_at 0.3337 0.0774
GSE97050 TXNL4B 54957 A_24_P399083 0.1255 0.4978
SRP007169 TXNL4B 54957 RNAseq 0.7852 0.0879
SRP008496 TXNL4B 54957 RNAseq 0.6578 0.1296
SRP064894 TXNL4B 54957 RNAseq 0.2359 0.0340
SRP133303 TXNL4B 54957 RNAseq 0.4717 0.0000
SRP159526 TXNL4B 54957 RNAseq 0.2829 0.3035
SRP193095 TXNL4B 54957 RNAseq 0.0494 0.5751
SRP219564 TXNL4B 54957 RNAseq -0.3064 0.4068
TCGA TXNL4B 54957 RNAseq 0.0481 0.4080

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TXNL4B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TXNL4B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TXNL4B 54957 4 0 26
GSE20123 TXNL4B 54957 4 0 26
GSE43470 TXNL4B 54957 2 8 33
GSE46452 TXNL4B 54957 38 2 19
GSE47630 TXNL4B 54957 11 8 21
GSE54993 TXNL4B 54957 2 4 64
GSE54994 TXNL4B 54957 8 10 35
GSE60625 TXNL4B 54957 4 0 7
GSE74703 TXNL4B 54957 2 5 29
GSE74704 TXNL4B 54957 2 0 18
TCGA TXNL4B 54957 25 15 56

Total number of gains: 102; Total number of losses: 52; Total Number of normals: 334.  

 

Somatic mutations of TXNL4B:

 

Generating mutation plots.

 

Highly correlated genes for TXNL4B:

 

Showing top 20/363 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TXNL4BTIMM220.693979303
TXNL4BGPR1800.666715505
TXNL4BMED200.65946605
TXNL4BBMS10.657436404
TXNL4BWDR660.654398404
TXNL4BPMCH0.649836303
TXNL4BACSF30.647231303
TXNL4BCOL24A10.643093504
TXNL4BFBXL80.641449303
TXNL4BPHC30.6378403
TXNL4BEMC10.628964604
TXNL4BTP53BP10.628606606
TXNL4BAAR20.626568403
TXNL4BTOMM340.626362604
TXNL4BFAM24B0.624389303
TXNL4BTTPAL0.621799403
TXNL4BATG1010.616521706
TXNL4BSPRY4-IT10.616223303
TXNL4BHOXC90.615467504
TXNL4BSUV39H20.615354504

For details and further investigation, click here