| Full name: nucleolar protein 8 | Alias Symbol: FLJ20736|Nop132 | ||
| Type: protein-coding gene | Cytoband: 9q22.31 | ||
| Entrez ID: 55035 | HGNC ID: HGNC:23387 | Ensembl Gene: ENSG00000198000 | OMIM ID: 611534 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOL8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOL8 | 55035 | 218244_at | 0.3165 | 0.5486 | |
| GSE20347 | NOL8 | 55035 | 218244_at | 0.2971 | 0.0277 | |
| GSE23400 | NOL8 | 55035 | 218244_at | 0.5486 | 0.0000 | |
| GSE26886 | NOL8 | 55035 | 218244_at | 0.5520 | 0.0427 | |
| GSE29001 | NOL8 | 55035 | 218244_at | 0.3802 | 0.2942 | |
| GSE38129 | NOL8 | 55035 | 218244_at | 0.3749 | 0.0001 | |
| GSE45670 | NOL8 | 55035 | 218244_at | 0.3538 | 0.0103 | |
| GSE53622 | NOL8 | 55035 | 16324 | 0.0869 | 0.1037 | |
| GSE53624 | NOL8 | 55035 | 16324 | 0.3503 | 0.0000 | |
| GSE63941 | NOL8 | 55035 | 218244_at | -0.0286 | 0.9636 | |
| GSE77861 | NOL8 | 55035 | 218244_at | 0.5925 | 0.0345 | |
| GSE97050 | NOL8 | 55035 | A_23_P71591 | 0.0062 | 0.9849 | |
| SRP007169 | NOL8 | 55035 | RNAseq | 1.0195 | 0.0210 | |
| SRP008496 | NOL8 | 55035 | RNAseq | 0.8880 | 0.0034 | |
| SRP064894 | NOL8 | 55035 | RNAseq | 0.5244 | 0.0007 | |
| SRP133303 | NOL8 | 55035 | RNAseq | 0.3452 | 0.0399 | |
| SRP159526 | NOL8 | 55035 | RNAseq | -0.0090 | 0.9684 | |
| SRP193095 | NOL8 | 55035 | RNAseq | 0.1463 | 0.1772 | |
| SRP219564 | NOL8 | 55035 | RNAseq | 0.3829 | 0.2746 | |
| TCGA | NOL8 | 55035 | RNAseq | 0.1151 | 0.0264 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NOL8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOL8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOL8 | 55035 | 6 | 9 | 15 | |
| GSE20123 | NOL8 | 55035 | 6 | 9 | 15 | |
| GSE43470 | NOL8 | 55035 | 6 | 4 | 33 | |
| GSE46452 | NOL8 | 55035 | 6 | 14 | 39 | |
| GSE47630 | NOL8 | 55035 | 1 | 17 | 22 | |
| GSE54993 | NOL8 | 55035 | 4 | 2 | 64 | |
| GSE54994 | NOL8 | 55035 | 8 | 11 | 34 | |
| GSE60625 | NOL8 | 55035 | 0 | 0 | 11 | |
| GSE74703 | NOL8 | 55035 | 5 | 3 | 28 | |
| GSE74704 | NOL8 | 55035 | 3 | 7 | 10 | |
| TCGA | NOL8 | 55035 | 24 | 24 | 48 |
Total number of gains: 69; Total number of losses: 100; Total Number of normals: 319.
Somatic mutations of NOL8:
Generating mutation plots.
Highly correlated genes for NOL8:
Showing top 20/839 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOL8 | SLC25A29 | 0.769555 | 3 | 0 | 3 |
| NOL8 | CBFA2T2 | 0.763986 | 3 | 0 | 3 |
| NOL8 | ERGIC1 | 0.75078 | 3 | 0 | 3 |
| NOL8 | TMTC4 | 0.750088 | 3 | 0 | 3 |
| NOL8 | NBEAL1 | 0.749078 | 3 | 0 | 3 |
| NOL8 | CDCA7 | 0.74211 | 3 | 0 | 3 |
| NOL8 | ZNF600 | 0.740442 | 3 | 0 | 3 |
| NOL8 | ZNF146 | 0.731178 | 6 | 0 | 5 |
| NOL8 | ZNF566 | 0.721196 | 3 | 0 | 3 |
| NOL8 | ZNF680 | 0.71606 | 3 | 0 | 3 |
| NOL8 | DICER1 | 0.715898 | 3 | 0 | 3 |
| NOL8 | PLEKHA3 | 0.714378 | 3 | 0 | 3 |
| NOL8 | ZNF260 | 0.710074 | 4 | 0 | 3 |
| NOL8 | ZNF669 | 0.709786 | 3 | 0 | 3 |
| NOL8 | CEP95 | 0.709037 | 4 | 0 | 3 |
| NOL8 | ZNF567 | 0.707313 | 4 | 0 | 3 |
| NOL8 | POGK | 0.706415 | 4 | 0 | 4 |
| NOL8 | NSMCE4A | 0.700334 | 3 | 0 | 3 |
| NOL8 | ZNF791 | 0.698269 | 4 | 0 | 4 |
| NOL8 | HERPUD2 | 0.697589 | 3 | 0 | 3 |
For details and further investigation, click here
