POGK

 

Full name: pogo transposable element derived with KRAB domain Alias Symbol: KIAA15131|LST003|BASS2|KRBOX2
Type: protein-coding gene Cytoband: 1q24.1
Entrez ID: 57645 HGNC ID: HGNC:18800 Ensembl Gene: ENSG00000143157 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of POGK:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 POGK 57645 218229_s_at 0.7196 0.0940
GSE20347 POGK 57645 218229_s_at 0.0536 0.8404
GSE23400 POGK 57645 218229_s_at 0.3646 0.0000
GSE26886 POGK 57645 218229_s_at -0.7461 0.0381
GSE29001 POGK 57645 218229_s_at 0.4011 0.2083
GSE38129 POGK 57645 218229_s_at 0.3461 0.0358
GSE45670 POGK 57645 218229_s_at 0.0380 0.8050
GSE53622 POGK 57645 89661 0.3785 0.0000
GSE53624 POGK 57645 89661 0.2824 0.0000
GSE63941 POGK 57645 218229_s_at 1.0280 0.0027
GSE77861 POGK 57645 218229_s_at 0.3552 0.2060
GSE97050 POGK 57645 A_23_P137715 0.1061 0.6083
SRP007169 POGK 57645 RNAseq -0.0192 0.9570
SRP008496 POGK 57645 RNAseq 0.3825 0.0770
SRP064894 POGK 57645 RNAseq 0.1712 0.1810
SRP133303 POGK 57645 RNAseq 0.2084 0.1350
SRP159526 POGK 57645 RNAseq 0.3973 0.0419
SRP193095 POGK 57645 RNAseq 0.1294 0.2285
SRP219564 POGK 57645 RNAseq 0.3759 0.2282
TCGA POGK 57645 RNAseq 0.1187 0.0095

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by POGK expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of POGK:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 POGK 57645 10 1 19
GSE20123 POGK 57645 10 1 19
GSE43470 POGK 57645 7 2 34
GSE46452 POGK 57645 2 1 56
GSE47630 POGK 57645 14 0 26
GSE54993 POGK 57645 0 5 65
GSE54994 POGK 57645 16 0 37
GSE60625 POGK 57645 0 0 11
GSE74703 POGK 57645 7 2 27
GSE74704 POGK 57645 4 0 16
TCGA POGK 57645 44 3 49

Total number of gains: 114; Total number of losses: 15; Total Number of normals: 359.  


 

Somatic mutations of POGK:

 

Generating mutation plots.

 

Highly correlated genes for POGK:

 

Showing top 20/978 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
POGKGOSR10.811969303
POGKHSPBP10.806413303
POGKPCNT0.804224303
POGKMRPS60.795789303
POGKFAM193A0.789522303
POGKTGFBRAP10.781139303
POGKPPP1R15B0.773477303
POGKZNF7650.761508303
POGKEXD20.755946303
POGKRNF2170.742412303
POGKDCUN1D40.738946303
POGKGATAD2B0.738264505
POGKSETMAR0.735303303
POGKZNF518B0.732054403
POGKERP270.730048303
POGKTRIM440.729232303
POGKZNF8790.728337303
POGKUBR70.721273403
POGKRIMKLB0.717169303
POGKC2orf760.716163303

For details and further investigation, click here