| Full name: zinc finger protein 680 | Alias Symbol: FLJ90430 | ||
| Type: protein-coding gene | Cytoband: 7q11.21 | ||
| Entrez ID: 340252 | HGNC ID: HGNC:26897 | Ensembl Gene: ENSG00000173041 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF680:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF680 | 340252 | 229533_x_at | 0.8077 | 0.1383 | |
| GSE26886 | ZNF680 | 340252 | 229533_x_at | 0.7258 | 0.0018 | |
| GSE45670 | ZNF680 | 340252 | 229533_x_at | 0.1444 | 0.5885 | |
| GSE53622 | ZNF680 | 340252 | 66727 | 0.6872 | 0.0000 | |
| GSE53624 | ZNF680 | 340252 | 106856 | 0.3645 | 0.0122 | |
| GSE63941 | ZNF680 | 340252 | 229533_x_at | -0.4087 | 0.6354 | |
| GSE77861 | ZNF680 | 340252 | 229533_x_at | -0.1733 | 0.5230 | |
| GSE97050 | ZNF680 | 340252 | A_33_P3245734 | 0.5480 | 0.0899 | |
| SRP007169 | ZNF680 | 340252 | RNAseq | 1.0796 | 0.0212 | |
| SRP008496 | ZNF680 | 340252 | RNAseq | 1.0638 | 0.0004 | |
| SRP064894 | ZNF680 | 340252 | RNAseq | 0.0023 | 0.9941 | |
| SRP133303 | ZNF680 | 340252 | RNAseq | 0.4785 | 0.0089 | |
| SRP159526 | ZNF680 | 340252 | RNAseq | 0.0620 | 0.8251 | |
| SRP193095 | ZNF680 | 340252 | RNAseq | 0.4930 | 0.0018 | |
| SRP219564 | ZNF680 | 340252 | RNAseq | 0.4556 | 0.1250 | |
| TCGA | ZNF680 | 340252 | RNAseq | -0.0697 | 0.4784 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZNF680 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF680:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF680 | 340252 | 11 | 2 | 17 | |
| GSE20123 | ZNF680 | 340252 | 10 | 2 | 18 | |
| GSE43470 | ZNF680 | 340252 | 2 | 1 | 40 | |
| GSE46452 | ZNF680 | 340252 | 13 | 0 | 46 | |
| GSE47630 | ZNF680 | 340252 | 7 | 1 | 32 | |
| GSE54993 | ZNF680 | 340252 | 2 | 7 | 61 | |
| GSE54994 | ZNF680 | 340252 | 13 | 4 | 36 | |
| GSE60625 | ZNF680 | 340252 | 0 | 0 | 11 | |
| GSE74703 | ZNF680 | 340252 | 2 | 1 | 33 | |
| GSE74704 | ZNF680 | 340252 | 5 | 1 | 14 | |
| TCGA | ZNF680 | 340252 | 45 | 5 | 46 |
Total number of gains: 110; Total number of losses: 24; Total Number of normals: 354.
Somatic mutations of ZNF680:
Generating mutation plots.
Highly correlated genes for ZNF680:
Showing top 20/417 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF680 | LIN9 | 0.835289 | 3 | 0 | 3 |
| ZNF680 | RAB3IP | 0.832755 | 3 | 0 | 3 |
| ZNF680 | LRRC58 | 0.803596 | 3 | 0 | 3 |
| ZNF680 | HS6ST1 | 0.790369 | 3 | 0 | 3 |
| ZNF680 | NCAPD3 | 0.782754 | 3 | 0 | 3 |
| ZNF680 | CPSF6 | 0.77973 | 3 | 0 | 3 |
| ZNF680 | PTPN4 | 0.773432 | 3 | 0 | 3 |
| ZNF680 | THADA | 0.771331 | 3 | 0 | 3 |
| ZNF680 | DSCC1 | 0.771097 | 3 | 0 | 3 |
| ZNF680 | HOXD8 | 0.77091 | 3 | 0 | 3 |
| ZNF680 | TCF3 | 0.76997 | 3 | 0 | 3 |
| ZNF680 | MCMBP | 0.76518 | 3 | 0 | 3 |
| ZNF680 | FAM161A | 0.764423 | 3 | 0 | 3 |
| ZNF680 | GTPBP8 | 0.761763 | 3 | 0 | 3 |
| ZNF680 | NAT10 | 0.76084 | 3 | 0 | 3 |
| ZNF680 | HNRNPR | 0.759801 | 3 | 0 | 3 |
| ZNF680 | EHMT2 | 0.759479 | 3 | 0 | 3 |
| ZNF680 | SRRT | 0.754567 | 3 | 0 | 3 |
| ZNF680 | LETM1 | 0.753011 | 3 | 0 | 3 |
| ZNF680 | DHX33 | 0.7495 | 3 | 0 | 3 |
For details and further investigation, click here
