| Full name: CBFA2/RUNX1 partner transcriptional co-repressor 2 | Alias Symbol: MTGR1|ZMYND3 | ||
| Type: protein-coding gene | Cytoband: 20q11.21-q11.22 | ||
| Entrez ID: 9139 | HGNC ID: HGNC:1536 | Ensembl Gene: ENSG00000078699 | OMIM ID: 603672 |
| Drug and gene relationship at DGIdb | |||
Expression of CBFA2T2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CBFA2T2 | 9139 | 238549_at | 0.8127 | 0.3399 | |
| GSE20347 | CBFA2T2 | 9139 | 207625_s_at | 0.0649 | 0.6976 | |
| GSE23400 | CBFA2T2 | 9139 | 207625_s_at | 0.0149 | 0.7648 | |
| GSE26886 | CBFA2T2 | 9139 | 207625_s_at | 0.0976 | 0.7811 | |
| GSE29001 | CBFA2T2 | 9139 | 207625_s_at | 0.2752 | 0.2731 | |
| GSE38129 | CBFA2T2 | 9139 | 207625_s_at | 0.0980 | 0.5470 | |
| GSE45670 | CBFA2T2 | 9139 | 238549_at | 0.5168 | 0.0501 | |
| GSE53622 | CBFA2T2 | 9139 | 148430 | 0.3719 | 0.0001 | |
| GSE53624 | CBFA2T2 | 9139 | 148842 | -0.1042 | 0.1261 | |
| GSE63941 | CBFA2T2 | 9139 | 238549_at | 0.8777 | 0.1904 | |
| GSE77861 | CBFA2T2 | 9139 | 238549_at | 0.9562 | 0.0331 | |
| GSE97050 | CBFA2T2 | 9139 | A_33_P3265950 | 0.0061 | 0.9849 | |
| SRP007169 | CBFA2T2 | 9139 | RNAseq | -0.3323 | 0.3611 | |
| SRP008496 | CBFA2T2 | 9139 | RNAseq | 0.2266 | 0.3735 | |
| SRP064894 | CBFA2T2 | 9139 | RNAseq | 0.2611 | 0.1833 | |
| SRP133303 | CBFA2T2 | 9139 | RNAseq | -0.0880 | 0.4202 | |
| SRP159526 | CBFA2T2 | 9139 | RNAseq | 0.6787 | 0.0942 | |
| SRP193095 | CBFA2T2 | 9139 | RNAseq | 0.0754 | 0.5041 | |
| SRP219564 | CBFA2T2 | 9139 | RNAseq | 0.4755 | 0.0985 | |
| TCGA | CBFA2T2 | 9139 | RNAseq | 0.0738 | 0.1594 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CBFA2T2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CBFA2T2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CBFA2T2 | 9139 | 15 | 0 | 15 | |
| GSE20123 | CBFA2T2 | 9139 | 15 | 0 | 15 | |
| GSE43470 | CBFA2T2 | 9139 | 12 | 0 | 31 | |
| GSE46452 | CBFA2T2 | 9139 | 29 | 0 | 30 | |
| GSE47630 | CBFA2T2 | 9139 | 24 | 1 | 15 | |
| GSE54993 | CBFA2T2 | 9139 | 0 | 20 | 50 | |
| GSE54994 | CBFA2T2 | 9139 | 25 | 1 | 27 | |
| GSE60625 | CBFA2T2 | 9139 | 0 | 0 | 11 | |
| GSE74703 | CBFA2T2 | 9139 | 11 | 0 | 25 | |
| GSE74704 | CBFA2T2 | 9139 | 10 | 0 | 10 | |
| TCGA | CBFA2T2 | 9139 | 51 | 1 | 44 |
Total number of gains: 192; Total number of losses: 23; Total Number of normals: 273.
Somatic mutations of CBFA2T2:
Generating mutation plots.
Highly correlated genes for CBFA2T2:
Showing top 20/510 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CBFA2T2 | GPATCH2 | 0.854394 | 3 | 0 | 3 |
| CBFA2T2 | WDR75 | 0.849048 | 3 | 0 | 3 |
| CBFA2T2 | COPS5 | 0.845979 | 3 | 0 | 3 |
| CBFA2T2 | METTL8 | 0.841015 | 3 | 0 | 3 |
| CBFA2T2 | SLC5A3 | 0.836808 | 3 | 0 | 3 |
| CBFA2T2 | ALKBH6 | 0.815344 | 3 | 0 | 3 |
| CBFA2T2 | SSB | 0.784296 | 3 | 0 | 3 |
| CBFA2T2 | NUDCD1 | 0.784176 | 3 | 0 | 3 |
| CBFA2T2 | ZNF284 | 0.777515 | 3 | 0 | 3 |
| CBFA2T2 | SLC25A32 | 0.777231 | 3 | 0 | 3 |
| CBFA2T2 | OTUD6B | 0.776271 | 3 | 0 | 3 |
| CBFA2T2 | ZC3H15 | 0.77627 | 3 | 0 | 3 |
| CBFA2T2 | COMMD5 | 0.774559 | 3 | 0 | 3 |
| CBFA2T2 | C8orf76 | 0.774255 | 3 | 0 | 3 |
| CBFA2T2 | PFDN2 | 0.773754 | 3 | 0 | 3 |
| CBFA2T2 | NUFIP2 | 0.77251 | 3 | 0 | 3 |
| CBFA2T2 | TRMT12 | 0.764691 | 3 | 0 | 3 |
| CBFA2T2 | NOL8 | 0.763986 | 3 | 0 | 3 |
| CBFA2T2 | DCAF16 | 0.762107 | 3 | 0 | 3 |
| CBFA2T2 | CPNE8 | 0.760659 | 3 | 0 | 3 |
For details and further investigation, click here
