| Full name: endoplasmic reticulum-golgi intermediate compartment 1 | Alias Symbol: ERGIC32|ERGIC-32|KIAA1181|NET24 | ||
| Type: protein-coding gene | Cytoband: 5q35.1 | ||
| Entrez ID: 57222 | HGNC ID: HGNC:29205 | Ensembl Gene: ENSG00000113719 | OMIM ID: 617946 |
| Drug and gene relationship at DGIdb | |||
Expression of ERGIC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERGIC1 | 57222 | 224576_at | 0.2400 | 0.6018 | |
| GSE26886 | ERGIC1 | 57222 | 224576_at | -0.0184 | 0.9393 | |
| GSE45670 | ERGIC1 | 57222 | 224576_at | -0.1723 | 0.3363 | |
| GSE53622 | ERGIC1 | 57222 | 1551 | -0.0992 | 0.1224 | |
| GSE53624 | ERGIC1 | 57222 | 1551 | -0.0248 | 0.6875 | |
| GSE63941 | ERGIC1 | 57222 | 224576_at | -1.7932 | 0.0066 | |
| GSE77861 | ERGIC1 | 57222 | 224576_at | 0.1608 | 0.6496 | |
| GSE97050 | ERGIC1 | 57222 | A_24_P97770 | 0.1197 | 0.7337 | |
| SRP007169 | ERGIC1 | 57222 | RNAseq | -0.8888 | 0.0035 | |
| SRP008496 | ERGIC1 | 57222 | RNAseq | -0.9750 | 0.0000 | |
| SRP064894 | ERGIC1 | 57222 | RNAseq | -0.2552 | 0.1366 | |
| SRP133303 | ERGIC1 | 57222 | RNAseq | 0.0722 | 0.6731 | |
| SRP159526 | ERGIC1 | 57222 | RNAseq | -0.1559 | 0.6282 | |
| SRP193095 | ERGIC1 | 57222 | RNAseq | -0.0996 | 0.5376 | |
| SRP219564 | ERGIC1 | 57222 | RNAseq | 0.3123 | 0.4699 | |
| TCGA | ERGIC1 | 57222 | RNAseq | -0.2824 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ERGIC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERGIC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERGIC1 | 57222 | 2 | 13 | 15 | |
| GSE20123 | ERGIC1 | 57222 | 2 | 13 | 15 | |
| GSE43470 | ERGIC1 | 57222 | 2 | 10 | 31 | |
| GSE46452 | ERGIC1 | 57222 | 0 | 27 | 32 | |
| GSE47630 | ERGIC1 | 57222 | 0 | 20 | 20 | |
| GSE54993 | ERGIC1 | 57222 | 9 | 2 | 59 | |
| GSE54994 | ERGIC1 | 57222 | 2 | 15 | 36 | |
| GSE60625 | ERGIC1 | 57222 | 1 | 0 | 10 | |
| GSE74703 | ERGIC1 | 57222 | 2 | 7 | 27 | |
| GSE74704 | ERGIC1 | 57222 | 1 | 6 | 13 | |
| TCGA | ERGIC1 | 57222 | 8 | 34 | 54 |
Total number of gains: 29; Total number of losses: 147; Total Number of normals: 312.
Somatic mutations of ERGIC1:
Generating mutation plots.
Highly correlated genes for ERGIC1:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERGIC1 | ZNF432 | 0.8253 | 3 | 0 | 3 |
| ERGIC1 | MSL3 | 0.820951 | 3 | 0 | 3 |
| ERGIC1 | ZNF669 | 0.819493 | 3 | 0 | 3 |
| ERGIC1 | MLEC | 0.808894 | 3 | 0 | 3 |
| ERGIC1 | SLC25A20 | 0.802365 | 3 | 0 | 3 |
| ERGIC1 | GMEB2 | 0.801808 | 3 | 0 | 3 |
| ERGIC1 | NUBPL | 0.789546 | 3 | 0 | 3 |
| ERGIC1 | HNRNPUL1 | 0.785313 | 3 | 0 | 3 |
| ERGIC1 | ITGB5 | 0.781012 | 3 | 0 | 3 |
| ERGIC1 | USP4 | 0.760569 | 3 | 0 | 3 |
| ERGIC1 | DCLRE1C | 0.757948 | 3 | 0 | 3 |
| ERGIC1 | RBM39 | 0.757737 | 3 | 0 | 3 |
| ERGIC1 | TRIM8 | 0.757558 | 3 | 0 | 3 |
| ERGIC1 | KLHL28 | 0.753682 | 3 | 0 | 3 |
| ERGIC1 | UBQLN4 | 0.75264 | 3 | 0 | 3 |
| ERGIC1 | NOL8 | 0.75078 | 3 | 0 | 3 |
| ERGIC1 | ZNF626 | 0.750047 | 3 | 0 | 3 |
| ERGIC1 | AMOTL2 | 0.746368 | 3 | 0 | 3 |
| ERGIC1 | ARHGAP35 | 0.746034 | 3 | 0 | 3 |
| ERGIC1 | THOC2 | 0.745112 | 3 | 0 | 3 |
For details and further investigation, click here
